Colter Shaw is a career "reward-seeker", making his living traveling the country and locating missing persons, collecting reward money in return. So it is not unusual when a wealthy entrepreneur hires him to track down his wife, an enigmatic artist who vanished one month before. As Shaw begins to investigate, he suspects that she was fleeing a bad marriage, and he follows her trail to an artists' retreat in Indiana. The case takes one surprising turn after another, and soon, Shaw begins to wonder if this mysterious woman is more of a captor than a captive.

Lincoln Rhyme was once a brilliant criminologist, a genius in the field of forensics - until an accident left him physically and emotionally shattered. But now a diabolical killer is challenging Rhyme to a terrifying and ingenious duel of wits. With police detective Amelia Sachs by his side, Rhyme must follow a labyrinth of clues that reaches back to a dark chapter in New York City’s past - and reach further into the darkness of the mind of a madman who won’t stop until he has stripped life down to the bone.

Carmen Sanchez is a tough Homeland Security agent who plays by the rules. But when her sister is attacked, revealing a connection to a series of murders across Southern California, she realizes a conventional investigation will not be enough to stop the ruthless perpetrator. With nowhere else to turn, Sanchez enlists the aid of Professor Jake Heron, a brilliant and quirky private security expert who, unlike Sanchez, believes rules are merely suggestions. The two have a troubled past, but he owes her a favor and she’s cashing in.

Ten years ago in California, Daniel Pell, a self-styled Charles Manson, was sentenced to life in prison for murdering an entire family: husband, wife, and two children, plus one of his young male followers. He is brought to Salinas, California, to interview with Kathryn Dance after he is implicated in yet another killing. Things go terribly wrong during an interview break, and Pell escapes, intent on killing again.

Renée Ballard works the night shift in Hollywood, beginning many investigations but finishing none, as each morning she turns her cases over to day shift detectives. A once up-and-coming detective, she's been given this beat as punishment after filing a sexual harassment complaint against a supervisor. But one night she catches two cases she doesn't want to part with: the brutal beating of a prostitute left for dead in a parking lot and the killing of a young woman in a nightclub shooting. Ballard is determined not to give up at dawn.