Humanity has nearly destroyed its world through global warming, but now an even greater evil lurks. The indigenous people of North America are being hunted and harvested for their bone marrow, which carries the key to recovering something the rest of the population has lost: the ability to dream. In this dark world, Frenchie and his companions struggle to survive as they make their way up north to the old lands. For now, survival means staying hidden—but what they don't know is that one of them holds the secret to defeating the marrow thieves.

Winifred has lived in the apartment above the cemetery office with her father, who works in the crematorium, all her life, close to her mother's grave. With her sixteenth birthday only days away, Winifred has settled into a lazy summer schedule, lugging her obese Chihuahua around the grounds in a squeaky red wagon to visit the neglected gravesides and nursing a serious crush on her best friend, Jack.

With winter looming, a small northern Anishinaabe community goes dark. Cut off, people become passive and confused. Panic builds as the food supply dwindles. While the band council and a pocket of community members struggle to maintain order, an unexpected visitor arrives, escaping the crumbling society to the south. Soon after, others follow. Frustrated by the building chaos, a group of young friends and their families turn to the land and Anishinaabe tradition in hopes of helping their community thrive again.

In the real world, Bugz is a shy and self-conscious Indigenous teen who faces the stresses of teenage angst and life on the Rez. But in the virtual world, her alter ego is not just confident but dominant in a massively multiplayer video game universe.

Eighteen-year-old Daunis Fontaine has never quite fit in, both in her hometown and on the nearby Ojibwe reservation. She dreams of a fresh start at college, but when family tragedy strikes, Daunis puts her future on hold to look after her fragile mother. The only bright spot is meeting Jamie, the charming new recruit on her brother Levi’s hockey team. Yet even as Daunis falls for Jamie, she senses the dashing hockey star is hiding something. Everything comes to light when Daunis witnesses a shocking murder, thrusting her into an FBI investigation of a lethal new drug.

When Will returns to Medicine River, he thinks he is simply attending his mother’s funeral. He doesn’t count on Harlen Bigbear and his unique brand of community planning. Harlen tries to sell Will on the idea of returning to Medicine River to open shop as the town’s only Native photographer. Somehow, that’s exactly what happens. Through Will’s gentle and humorous narrative, we come to know Medicine River, a small Albertan town bordering a Blackfoot reserve. And we meet its people: the basketball team; Louise Heavyman and her daughter, South Wing, and many more.

Otter Lake is a sleepy Anishnawbe community where little happens. Until the day a handsome stranger pulls up astride a 1953 Indian Chief motorcycle - and turns Otter Lake completely upside down. Maggie, the Reserve’s chief, is swept off her feet, but Virgil, her teenage son, is less than enchanted. Suspicious of the stranger’s intentions, he teams up with his uncle, Wayne - a master of aboriginal martial arts - to drive the stranger from the Reserve. And it turns out that the raccoons are willing to lend a hand.

Perry Firekeeper-Birch was ready for her Summer of Slack but instead, after a fender bender that was entirely not her fault, she’s stuck working to pay back her Auntie Daunis for repairs to the Jeep. Thankfully she has the other outcasts of the summer program. Together they ace obstacle courses, plan vigils for missing women in the community, and make sure summer doesn’t feel so lost after all. But when she attends a meeting at a local university, Perry learns about the “Warrior Girl”, an ancestor whose bones and knife are stored in the museum archives, and everything changes.

Morgan and Eli, two Indigenous children forced away from their families and communities, are brought together in a foster home in Winnipeg, Manitoba. They each feel disconnected, from their culture and each other, and struggle to fit in at school and at their new home—until they find a secret place, walled off in an unfinished attic bedroom. A portal opens to another reality, Askí, bringing them onto frozen, barren grounds, where they meet Ochek (Fisher).

When Garnet Raven was three years old, he was taken from his home on an Ojibway Indian reserve and placed in a series of foster homes. Having reached his mid-teens, he escapes at the first available opportunity, only to find himself cast adrift on the streets of the big city. Having skirted the urban underbelly once too often by age 20, he finds himself thrown in jail. While there, he gets a surprise letter from his long-forgotten native family. The sudden communication from his past spurs him to return to the reserve following his release from jail.