Dr. Brandt Savage is on sabbatical from the University of Chicago. Instead of doing solo fieldwork in anthropology, the gawky, bespectacled PhD finds himself enrolled in a school where he is the sole pupil. His professor, “Meed,” is demanding. She’s also his captor. Savage emerges from their intensive training sessions physically and mentally transformed, but with no idea why he’s been chosen, and how he’ll use his fearsome abilities. Then his first mission with Meed takes them back to her own training ground.

Alex Cross is a homicide detective with a Ph.D. in psychology. He works and lives in Southeast D.C. and looks like Muhammad Ali in his prime. He's a tough guy from a tough part of town who wears Harris Tweed jackets and likes to relax by banging out Gershwin tunes on his baby grand piano. But he also has two adorable kids of his own, and they are his own special vulnerabilities.

Two teens appear out of nowhere, ransacking a small-town grocery and attacking the police officers who come to investigate. Their clothes are torn and filthy, their hands and bare feet callused, they have fangs. They’re sister and brother, alone against the world. Where did they come from? Raised by wolves, they say. Kai and Holo are taken in by the police chief and his wife, and begin adjusting to life in a small town, attending school and going on dates. But humans, they find, are the most vicious animals. And the mystery of their upbringing brings dark and powerful forces to Kokanee Creek.

Tough-as-nails criminal defense attorney Jane Smith is hip-deep in the murder trial of the century. Actually, her charmless client might’ve committed several murders. She’s also fallen in love with a wonderful guy. And an equally wonderful dog, a mutt. But Jane doesn’t have much time. She’s just received a terminal diagnosis giving her twelve months. Unless she’s murdered before her expiration date.

Renée Ballard works the night shift in Hollywood, beginning many investigations but finishing none, as each morning she turns her cases over to day shift detectives. A once up-and-coming detective, she's been given this beat as punishment after filing a sexual harassment complaint against a supervisor. But one night she catches two cases she doesn't want to part with: the brutal beating of a prostitute left for dead in a parking lot and the killing of a young woman in a nightclub shooting. Ballard is determined not to give up at dawn.

Four young women have been found murdered—tortured and strangled in their own beds—all victims of the same brilliant monster. Using a skilled hand and the latest technology in forensic medicine, Kay Scarpetta begins the process of gathering the microscopic clues the latest battered body has to give.

Sydney Shaw, like every single woman in New York, has terrible luck with dating. She’s seen it all: men who lie in their dating profile, men who stick her with the dinner bill, and worst of all, men who can't shut up about their mothers. But finally, she hits the jackpot. Her new boyfriend is utterly perfect. He's charming, handsome, and works as a doctor at a local hospital. Sydney is swept off her feet. Then the brutal murder of a young woman—the latest in a string of deaths across the coast—confounds police. The primary suspect? A mystery man who dates his victims before he kills them.

Every day without fail, Travis Devine puts on a cheap suit, grabs his faux-leather briefcase, and boards the 6:20 commuter train to Manhattan, where he works as an entry-level analyst at the city’s most prestigious investment firm. In the mornings, he gazes out the train window at the lavish homes of the uberwealthy, dreaming about joining their ranks. In the evenings, he listens to the fiscal news on his phone, already preparing for the next grueling day in the cutthroat realm of finance. Then one morning Devine’s tedious routine is shattered by an anonymous email: She is dead.

Hollows Bend, New Hampshire, is a picture-perfect New England town where weekend tourists flock to see fall leaves and eat breakfast at the Stairway Diner. The crime rate—zero—is a point of pride for Sheriff Ellie Pritchett. The day the stranger shows up is when the trouble starts. The sheriff and her deputy investigate the mysterious teenage girl. None of the locals can place her. She can’t—or won’t—answer any questions. She won’t even tell them her name.

From Atlanta's wealthiest suburbs to its stark inner-city housing projects, a killer has crossed the boundaries of wealth and race. And the people who are chasing him must cross those boundaries, too. Among them is Michael Ormewood, a veteran detective whose marriage is hanging by a thread and whose arrogance and explosive temper are threatening his career. And Angie Polaski, a beautiful vice cop who was once Michael's lover before she became his enemy.