On October 6, 1973, Ted Simon knew there was no going back. He loaded up his 500cc Triumph Tiger in the pouring rain and said good-bye to London. Over four years he rode 64,000 miles round the world. Breakdowns, revolutions, war, a spell in prison, and a Californian commune were all part of his experience, which was colored variously by utter despair and unimaginable joy. He was treated as a spy, a god, a welcome stranger and a curiosity

In less than a year, Neil Peart lost both his 19-year-old daughter, Selena, and his wife, Jackie. Faced with overwhelming sadness and isolated from the world in his home on the lake, Peart was left without direction. That lack of direction lead him on a 55,000 mile journey by motorcycle across much of North America, down through Mexico to Belize, and back again.

In 1982, at the age of just 23 and halfway through her architecture studies, Elspeth Beard left her family and friends in London and set off on a 35,000-mile solo adventure around the world on her 1974 BMW R60/6. Reeling from a recent breakup and with only limited savings from her pub job, a tent, a few clothes, and some tools, all packed on the back of her bike, she was determined to prove herself. She had ridden bikes since her teens and was well-traveled. But nothing could prepare her for what lay ahead.

The Motorcycle Diaries is Che Guevara's diary of his journey to discover the continent of Latin America while still a medical student, setting out in 1952 on a vintage Norton motorcycle together with his friend Alberto Granado, a biochemist. It captures, arguably as much as any book ever written, the exuberance and joy of one person's youthful belief in the possibilities of humankind tending toward justice, peace, and happiness.

Join the adventure as 33-year-old Rene Cormier politely removes himself from the working world that surrounds him and cashes in what few possessions he has to finance a three-year-long motorcycle journey around the world. Never one to let excessive planning get in the way of a good ride, Rene runs out of money half way through the tour and ultimately takes five years to cover the 41-country, 154,000 kilometer (95,000 mile) route.