When FBI special agent Luke Kendrick discovers chilling evidence of dozens of victims at a crime scene in London, he recognizes the calling card of the notorious H. H. Holmes Society. Named for the eighteenth-century monster regarded as America’s first serial killer, the society is comprised of a twisted web of killers, working to carry out heinous murders in Holmes’s memory. And now the group’s been linked to a Scottish castle turned B and B—where guests check in but never check out.

Deep in the Florida Everglades, the body of a woman is discovered in pieces, presumably ravaged by an alligator. Upon closer inspection, it’s determined no animal could make such perfectly precise cuts. Only a blade could do that. Wielded by a human. Soon, dozens of oil drums emerge amid the river of grass. Each one packed to the brim with body parts.

Four bodies have been discovered along Europe’s riverbanks, placed with care—and completely drained of blood. Pinpricks on their throats indicate a slender murder weapon, but DNA found in the wounds suggests something far more sinister. Tasked with investigating, the FBI recruits Agents Della Hamilton and Mason Carter to Blackbird, an international offshoot of the Krewe of Hunters. If you want to catch a vampire killer, you need agents who can speak with the dead.

A secret government unit is formed under the oversight of Adam Harrison, famed paranormal investigator. The case: In a historic mansion in New Orleans’ French Quarter, a senator’s wife falls to her death from a balcony. Most think she jumped, distraught over the loss of her young son. Some say she was pushed. And yet others believe she was beckoned by the ghostly spirits that inhabit the house - once the site of a serial killer’s grisly work.

When two hikers go missing within a series of daunting caves outside of Denver, Colorado, FDLE special agent Amy Larson and her partner, FBI special agent Hunter Forrest, have good reason to suspect foul play. The pair of hikers are only the latest to vanish after a rash of disappearances that’s left local law enforcement stumped. But in searching the dank caverns near the Arkansas River, the agents aren’t prepared for the horror they uncover: a muddy pit littered with corpses. Covered in bite marks. Made by human teeth.