Deep in the heart of Appalachia stands a crooked farmhouse miles from any road. The Morrows keep to themselves, and it's served them well so far. When girls go missing off the side of the highway, the cops don't knock on their door. Which is a good thing, seeing what's buried in the Morrows' backyard. But 19-year-old Michael Morrow isn't like the rest of his family. He doesn't take pleasure in the screams that echo through the trees.

A group of close friends gathers at a secluded cabin in the wintry mountains of Colorado for a final holiday hurrah. Instead, it may be their last stand. First a massive blizzard leaves them marooned. Then the more chilling realization: Something is lurking in the woods, watching them, waiting.... Now a weekend of family, friends, and fun has turned into a test of love and loyalty in the face of inhuman horrors. The only hope for those huddled inside is to fight - tooth and nail, bullet and blade - for their lives. Otherwise, they’ll end up like the monsters’ other victims: bright pools of blood on glittering snow, screams lost in the vast mountains.

Joe works at a facility that performs human experimentation. His work just followed him home. The government wanted to unlock hidden abilities in the human mind. They put subjects in extreme sensory deprivation. All the test subjects went violently insane. But the research continued. Today it has been perfected. Almost perfected.

Episode Thirteen takes them to every ghost hunter's holy grail: the Paranormal Research Foundation. This brooding, derelict mansion holds secrets and clues about bizarre experiments that took place there in the 1970s. It's also famously haunted, and the team hopes their scientific techniques and high tech gear will prove it. But as the house begins to reveal itself to them, proof of an afterlife might not be everything Matt dreamed of.

These people will give anything for the idols they worship, be they rock stars, actors or authors. Or even serial killers. Lori is just such a fanatic. Her obsession is with Edmund Cox, a man of sadistic cruelty who butchered more than 20 women. She’s gone so far as to forge a relationship with him, visiting him in prison and sending him letters on a regular basis. She will do anything to get close to him, so when he gives her a task, she eagerly accepts it. She has no idea of the horror that awaits her.

In a boarded-up house on a dead-end street at the edge of the wild Washington woods lives a family of three. A teenage girl who isn’t allowed outside, not after last time. A man who drinks alone in front of his TV, trying to ignore the gaps in his memory. And a house cat who loves napping and reading the Bible. An unspeakable secret binds them together, but when a new neighbor moves in next door, what is buried out among the birch trees may come back to haunt them all.

High up on the windswept cliffs of Pale Peak, Faye and Felix celebrate their new engagement. But soon, a chorus of ghastly noises erupts from the nearby woods: the screams of animals, the cries of children, and the mad babble of a hundred mournful voices. A dark figure looms near the windows in the dead of night, whispering to Faye. As the weather turns deadly, Felix discovers that his terrified fiancée isn't just mumbling in her sleep—she's whispering back.

Mary is a quiet middle-aged woman doing her best to blend into the background. Unremarkable. Invisible. Unknown even to herself. But lately, things have been changing inside Mary. Along with the hot flashes and body aches, she can’t look in a mirror without passing out, and the voices in her head have been urging her to do unspeakable things. Fired from her job in New York, she moves back to her hometown hoping to reconnect with her past and inner self. What she finds instead are visions of terrifying mutilated specters that come with increasing regularity.

Ana and Reid needed a lucky break. The horrifically complicated birth of their first child has left Ana paralyzed, bitter, and struggling: with mobility, with her relationship with Reid, with resentment for her baby. That's about to change with the words any New Yorker would love to hear—affordable housing lottery. They've won an apartment in the Deptford, one of Manhattan's most revered buildings. Reid dismisses disturbing events and Ana’s deep unease and paranoia as the price of living in New York—people are odd—but he can't explain the needle-like bite marks on the baby.

When Louise finds out her parents have died, she dreads going home. She doesn’t want to leave her daughter with her ex and fly to Charleston. She doesn’t want to deal with her family home, stuffed to the rafters with the remnants of her father’s academic career and her mother’s lifelong obsession with puppets and dolls. She doesn’t want to learn how to live without the two people who knew and loved her best in the world. Most of all, she doesn’t want to deal with her brother, Mark, who never left their hometown, gets fired from one job after another, and resents her success.

With his marriage on the rocks and his life in shambles, washed-up true-crime writer Lucas Graham is desperate for a comeback, one more shot at the best-selling success he once enjoyed. His chance comes when he's promised exclusive access to death row inmate Jeffrey Halcomb, the notorious cult leader and mass murderer who's ready to break his silence after 30 years, and who contacted Lucas personally from his maximum-security cell.

In the summer of 1994, psychologist Daniel Hill buys a rustic farmhouse nestled in the rolling hills of West Virginia. Along with his wife and teenage daughter, the family uproots their lives in Ohio and moves south. They are initially seduced by the natural beauty of the country setting. That soon changes when they discover a hidden room in the basement with a well, boarded shut and adorned with crucifixes. Local legends about the previous owner being an exorcist come to light, but by then, all Hell has broken loose.

As a young, queer couple who flip houses, Charlie and Eve can’t believe the killer deal they’ve just gotten on an old house in a picturesque neighborhood. As they’re working in the house one day, there’s a knock on the door. A man stands there with his family, claiming to have lived there years before and asking if it would be alright if he showed his kids around. People pleaser to a fault, Eve lets them in. As soon as the strangers enter their home, uncanny and inexplicable things start happening.

A strange plague called the "Gets" is decimating humanity on a global scale. It causes people to forget - small things at first, like where they left their keys... then the not-so-small things like how to drive, or the letters of the alphabet. Then their bodies forget how to function involuntarily - and there is no cure. But now, far below the surface of the Pacific Ocean, deep in the Marianas Trench, an heretofore unknown substance hailed as "ambrosia" has been discovered - a universal healer, from initial reports.

Once every year, Scoutmaster Tim Riggs leads a troop of boys into the Canadian wilderness for a weekend camping trip - a tradition as comforting and reliable as a good ghost story around a roaring bonfre. The boys are a tight-knit crew. There’s Kent, one of the most popular kids in school; Ephraim and Max, also well-liked and easygoing; then there’s Newt the nerd and Shelley the odd duck. For the most part, they all get along and are happy to be there - which makes Scoutmaster Tim’s job a little easier.