Dr. Sam Anderson is one of the most celebrated scientists in history. Ten years ago, he invented a device that changed the world forever. Now his life is about to be ripped apart—and his own creation may be to blame. One fateful morning, Sam discovers that his girlfriend has been murdered and that his daughter is accused of the crime. Sam believes she's innocent, but he can't prove it. There's only one thing he can do to save his daughter: confess to the crime. And so he does. But in the future, murderers aren't sent to prison. They're sent to the past.

Geophysicist Jack Greer believes he may finally have found the resting place of the meteorite that wiped out the dinosaurs 65 million years ago. A few miles off the Yucatán coast, Jack and a team of scientists tow an aging drilling platform over the impact crater with the aim of securing a sample. But buried deep beneath the earth lies a shocking discovery that threatens to shatter everything we think we know about our species.

At the end of the world, a groundbreaking scientific experiment will change everything. Dr. Laura Reynolds had it all. A job she loved. The respect of her peers. Student debt she was slowly chipping away at. And one day, it all went away. She saw the wrong thing—a colleague's mistake. And to escape, he framed her. Laura's only option is to join a secretive research project in Antarctica, where she hopes to keep practicing medicine and one day get her life back. But soon after arriving, she realizes that things aren't what they seem in this advanced facility.

In Atlanta, Dr. Peyton Shaw is awakened by the phone call she has dreaded for years. As the CDC's leading epidemiologist, she's among the first responders to outbreaks around the world. It's a lonely and dangerous job, but it's her life - and she's good at it. This time she may have met her match. In Kenya, an Ebola-like pathogen has infected two Americans. One lies at death's door. With the clock ticking, Peyton assembles her team and joins personnel from the Kenyan Ministry of Health and the WHO.

Drake, a retired police detective, receives a call in the dead of night from an alien-obsessed podcaster. He hastily departs for Montana the following morning. The phenomenon continues all over the globe. What are they? What do they mean? Britt is on assignment for a digital magazine when she encounters one of the Glass in a tragic boating accident, leaving her no choice but to follow the lead. Panic ensues as mysterious creatures are sighted.