To serial slayer Andrew Compton, murder is an art, the most intimate art. After feigning his own death to escape from prison, Compton makes his way to the United States with the sole ambition of bringing his “art” to new heights. Tortured by his own perverse desires, and drawn to possess and destroy young boys, Compton inadvertently joins forces with Jay Byrne, a dissolute playboy who has pushed his “art” to limits even Compton hadn’t previously imagined.

Joe works at a facility that performs human experimentation. His work just followed him home. The government wanted to unlock hidden abilities in the human mind. They put subjects in extreme sensory deprivation. All the test subjects went violently insane. But the research continued. Today it has been perfected. Almost perfected.

After his estranged father’s mysterious death, Charlie Remick returns to Seattle to help with the funeral. There, he discovers his father left him two parting gifts: the keys to the family record store and a strange black case containing four ancient records that, according to legend, can open a gate to the land of the dead. When Charlie, his sister, and their two friends play the records, they unwittingly open a floodgate of unspeakable horror. As the darkness descends, they are stalked by a relentless, malevolent force and see the dead everywhere they turn.

Deep in the heart of Appalachia stands a crooked farmhouse miles from any road. The Morrows keep to themselves, and it's served them well so far. When girls go missing off the side of the highway, the cops don't knock on their door. Which is a good thing, seeing what's buried in the Morrows' backyard. But 19-year-old Michael Morrow isn't like the rest of his family. He doesn't take pleasure in the screams that echo through the trees.

In the summer of 1994, psychologist Daniel Hill buys a rustic farmhouse nestled in the rolling hills of West Virginia. Along with his wife and teenage daughter, the family uproots their lives in Ohio and moves south. They are initially seduced by the natural beauty of the country setting. That soon changes when they discover a hidden room in the basement with a well, boarded shut and adorned with crucifixes. Local legends about the previous owner being an exorcist come to light, but by then, all Hell has broken loose.