Forty-four-year-old Alice Holtzman is stuck in a dead-end job, bereft of family, and now reeling from the unexpected death of her husband. Alice has begun having panic attacks whenever she thinks about how her life hasn't turned out the way she dreamed. Even the beloved honeybees she raises in her spare time aren't helping her feel better these days.

What you see isn’t always what you get. Take Ainsley. The gorgeous mother of two lives a picture-perfect life with her husband, Ben—aspiring politician and heir to a candy fortune—in suburban Washington, DC. But in reality, Ainsley has no idea what she’s doing and is terrified someone will figure out who she really is and where she came from.

1932. After the Great War took both her beloved brother and her fiancé, Violet Speedwell has become a "surplus woman," one of a generation doomed to a life of spinsterhood after the war killed so many young men. Yet Violet cannot reconcile herself to a life spent caring for her grieving, embittered mother. After countless meals of boiled eggs and dry toast, she saves enough to move out of her mother's place and into the town of Winchester, home to one of England's grandest cathedrals.

Lillian and Madison were unlikely roommates and yet inseparable friends at their elite boarding school. But then, Lillian had to leave the school unexpectedly in the wake of a scandal, and they’ve barely spoken since. Until now, when Lillian gets a letter from Madison pleading for her help. Madison’s twin stepkids are moving in with her family, and she wants Lillian to be their caretaker. However, there’s a catch: The twins spontaneously combust when they get agitated, flames igniting from their skin in a startling but beautiful way.

To her thousands of Instagram followers, Josephine Boateng is the brilliant, dazzling self-love expert, Dr. Jojo. But off-camera, Jo’s grappling with the intense pressures of her career and her love life is nonexistent thanks to an unrequited crush on her best friend, rom-com heartthrob Ezra Adelman. Then Ezra shows up to his thirtieth birthday party with her childhood bully on his arm—and Jo realizes it’s finally time to take her own advice. Enter Malcom Waters, the world’s newest literary darling.

Twenty-one-year-old Tanner Quimby needs a place to live. Preferably one where she can continue sitting around in sweatpants and playing video games nineteen hours a day. Since she has no credit or money to speak of, her options are limited, so when an opportunity to work as a live-in caregiver for an elderly woman falls into her lap, she takes it. The two start off their living arrangement happily ignoring each other until Tanner starts to notice things—weird things.

In 1970s Baltimore, 14-year-old Mary Jane loves cooking with her mother, singing in her church choir, and enjoying her family’s subscription to the Broadway Showtunes of the Month record club. Shy, quiet, and bookish, she’s glad when she lands a summer job as a nanny for the daughter of a local doctor. A respectable job, Mary Jane’s mother says. In a respectable house.

Evie Jones has dedicated her life and very limited funds working for Southern Service Paws, the company that matched her with the love of her life: Charlie, a service dog trained to assist with her epilepsy. But it’s no secret that the company has been struggling to make ends meet. It’s up to her and her longtime mentor and boss to throw the fundraiser of the century to keep the doors open.

Emma Townsend can sum up her situationship with hot-as-hell romantic red flag Finn Hughes in one word: almost. They almost dated in high school. They almost hooked up after college. They almost took things too far one magical night. Their whole story is one series of “almosts” and “nearlys,” and now they just kind of can’t stand each other. Like, at all. But this weekend, one of their mutuals is getting married...and Emma and Finn will have to pretend they don’t remember how disastrous it was the last time they were in a room together.

Years of trying unsuccessfully to conceive a child have broken more than Angie DeSaria’s heart. Following a painful divorce, she moves back to her small Pacific Northwest hometown and takes over management of her family’s restaurant. In West End, where life rises and falls like the tides, Angie’s fortunes will drastically change yet again when she meets and befriends a troubled young woman.

Survival for Ki Lim and Sang Ly is a daily battle at Stung Mean Chey, the largest municipal waste dump in all of Cambodia. They make their living scavenging recyclables from the trash. Life would be hard enough without the worry for their chronically ill child, Nisay, and the added expense of medicines that are not working. Just when things seem worst, Sang Ly learns a secret about the ill-tempered rent collector who comes demanding money - a secret that sets in motion a tide that will change the life of everyone it sweeps past.

She was a successful ad sales rep in Manhattan. He was a homeless 11-year-old panhandler on the street. He asked for spare change; she kept walking. But then something stopped her in her tracks, and she went back. And she continued to go back, again and again. They met up nearly every week for years and built an unexpected, life-changing friendship that has today spanned almost three decades.

Natural-born healer Emma Starling once had big plans for her life, but she’s lost her way. A medical school dropout, she’s come back to small-town Everton, New Hampshire, to care for her father, who is dying from a mysterious brain disease. Clive Starling has been hallucinating small animals, as well as having visions of the ghost of a long-dead naturalist, Ernest Harold Baynes, once known for letting wild animals live in his house. This ghost has been giving Clive some ideas on how to spend his final days.

Elisabetta, Marco, and Sandro grow up as the best of friends despite their differences. Elisabetta is a feisty beauty who dreams of becoming a novelist; Marco the brash and athletic son in a family of professional cyclists; and Sandro a Jewish mathematics prodigy, kind-hearted and thoughtful, the son of a lawyer and a doctor. Their friendship blossoms to love, with both Sandro and Marco hoping to win Elisabetta's heart.

Former child actor Fiona St. James dropped out of the spotlight after a spectacularly public crash and burn. The tabloids called her crazy and self-destructive and said she’d lost her mind. Now in her late twenties, Fiona believes her humiliating past is firmly behind her. She’s finally regained a modicum of privacy, and she won’t let anything—or anyone—mess it up.