When Clementine Kaye, archivist Beecher White's first childhood crush, shows up at the National Archives asking for his help, Beecher tries to impress her by showing her the secret vault where the president of the United States privately reviews classified documents. They accidentally happen upon a priceless artifact - and find themselves suddenly entangled in a web of deception, conspiracy, and murder.

In 1943, as the war against Nazi Germany raged abroad, President Franklin Roosevelt had a critical goal: a face-to-face sit-down with his allies Joseph Stalin and Winston Churchill. This first-ever meeting of the Big Three in Tehran, Iran, would decide some of the most crucial strategic details of the war. Yet when the Nazis found out about the meeting, their own secret plan took shape—an assassination plot that would’ve changed history.

Evan Smoak is a man with skills, resources, and a personal mission to help those with nowhere else to turn. He’s also a man with a dangerous past. Chosen as a child, he was raised and trained as an Orphan, an off-the-books black box program designed to create the perfect deniable intelligence asset: An assassin. Evan was Orphan X - until he broke with the program and used everything he learned to disappear. But now someone is on his tail.

Charlie and Oliver Caruso are brothers who work at Greene & Greene, a private bank so exclusive you need two million dollars just to be a client. But when the door of success slams in their faces, they're faced with an offer they can't refuse: three million dollars in an abandoned account. No one knows it exists, and even better, it doesn't belong to anyone.

Joey Morales was the last recruit of the government's full black operation, the Orphan Program. Trained to be an assassin until she washed out, she was rescued by Evan Smoak, the former agent known as Orphan X. Now Joey, a world-class hacker, starts training for one of her biggest challenges yet: having a normal life. Still a teenager, she discovers she loves music as much as hacking, if not more so. But as she carves out a space for herself, the one thing missing is a family to support her endeavors.