Detective Peter Decker of the LAPD is stunned when he gets the report. Someone has shattered the sanctuary of a remote yeshiva community in the California hills with an unimaginable crime. One of the women was brutally raped as she returned from the mikvah, the bathhouse where the cleansing ritual is performed.

Dr. Morton Handler practiced a strange brand of psychiatry. Among his specialties were fraud, extortion, and sexual manipulation. Handler paid for his sins when he was brutally murdered in his luxurious Pacific Palisades apartment. The police have no leads, but they do have one possible witness: seven-year-old Melody Quinn.

DI Nikki Galena: A police detective with nothing left to lose, she's seen a girl die in her arms, and her daughter will never leave the hospital again. She's gotten tough on the criminals she believes did this to her. Too tough. And now she's been given one final warning: make it work with her new sergeant, DS Joseph Easter, or she's out.

Death is reporter Jack McEvoy's beat: his calling, his obsession. But this time, death brings McEvoy the story he never wanted to write - and the mystery he desperately needs to solve. A serial killer of unprecedented savagery and cunning is at large. His targets: homicide cops, each haunted by a murder case he couldn't crack. The killer's calling card: a quotation from the works of Edgar Allan Poe. His latest victim is McEvoy's own brother. And his last...may be McEvoy himself.

Four young women have been found murdered—tortured and strangled in their own beds—all victims of the same brilliant monster. Using a skilled hand and the latest technology in forensic medicine, Kay Scarpetta begins the process of gathering the microscopic clues the latest battered body has to give.