Everyone in the small town of Denton is searching for Isabelle Coleman, a missing 17-year-old girl. All they've found so far is her phone and another girl they didn't even know was missing. Mute and completely unresponsive to the world around her, it's clear this mysterious girl has been damaged beyond repair. All Detective Josie Quinn can get from her is a name: Ramona. Currently suspended from the force for misconduct, Josie takes matters into her own hands as the name leads her to evidence linking the two girls.

It's June in Montreal, and Dr. Temperance Brennan, who has left a shaky marriage back home in North Carolina to take on the challenging assignment of Director of Forensic Anthropology for the province of Quebec, looks forward to a relaxing weekend in beautiful Quebec City. First, though, she must stop at a newly uncovered burial site in the heart of the city. The remains are probably old and only of archeological interest, but Tempe must make sure they're not a case for the police. One look at the decomposed and decapitated corpse, stored neatly in plastic bags, tells her she'll spend the weekend in the crime lab.

When a man is shot in the head, Bree Taggert and her new partner, veteran detective Dana Romano, respond to the call. They break the news to the victim’s ex-wife and learn the estranged couple’s five-year-old daughter was supposed to have been with him. What starts as a murder investigation quickly morphs into a desperate search for a missing child. The case stirs memories of Bree’s own traumatizing childhood. To find the little girl, Bree will have to relive her own terrifying past.

After the devastating loss of her husband in Iraq, Morgan Dane returns to Scarlet Falls, seeking the comfort of her hometown. Now, surrounded by family, she’s finally found peace and a promising career opportunity - until her babysitter is killed and her neighbor asks her to defend his son, Nick, who stands accused of the murder.

Frankie Elkin is an average middle-aged woman, a recovering alcoholic with more regrets than belongings. But she spends her life doing what no one else will - searching for missing people the world has stopped looking for. When the police have given up, when the public no longer remembers, when the media has never paid attention, Frankie starts looking. A new case brings her to Mattapan, a Boston neighborhood with a rough reputation. She is searching for Angelique Badeau, a Haitian teenager who vanished from her high school months earlier.