Patrick Lewis arrives in Toronto in the 1920s and earns his living searching for a vanished millionaire and tunneling beneath Lake Ontario. In the course of his adventures, Patrick's life intersects with those of characters who reappear in Ondaatje's Booker Prize-winning The English Patient.

Sixteen-year-old Nomi Nickel longs to hang out with Lou Reed and Marianne Faithfull in New York City's East Village. Instead she's trapped in East Village, Manitoba, a small town whose population is Mennonite: "the most embarrassing sub-sect of people to belong to if you're a teenager." East Village is a town with no train and no bar whose job prospects consist of slaughtering chickens at the Happy Family Farms abattoir or churning butter for tourists at the pioneer village.

Steven Rinella (The MeatEater Podcast) and Clay Newcomb (MeatEater's Bear Grease podcast) gather listeners for a new round of stories, this time drawing from the lives of the rugged Long Hunters, who include such figures as Daniel Boone, Henry Skaggs, and Kasper Mansker. These were the commercial hunters and trappers who explored and exploited the First Far West, the land across the Appalachian Mountains, in the era between the Seven Years War and the American Revolution—one of the most fabled periods of American history.

When the enslaved Jim overhears that he is about to be sold to a man in New Orleans, separated from his wife and daughter forever, he decides to hide on nearby Jackson Island until he can formulate a plan. Meanwhile, Huck Finn has faked his own death to escape his violent father, recently returned to town. As all readers of American literature know, thus begins the dangerous and transcendent journey by raft down the Mississippi River toward the elusive and too-often-unreliable promise of the Free States and beyond.

In 1866, with the country barely recovered from the Civil War, new war breaks out on the western frontier - a clash of cultures between a young, ambitious nation and the Native tribes who have lived on the land for centuries. Colonel Henry Carrington arrives in Wyoming’s Powder River Valley to lead the US Army in defending the opening of a new road for gold miners and settlers. Carrington intends to build a fort in the middle of critical hunting grounds, the home of the Lakota.