In 1977 Florida, nurse Deborah Clark, 23, is found brutally slain in her home. Detectives unearth an affair, a jilted wife, and a web of money and power, but no true suspect. It will take 40 years and advanced DNA testing to expose Deb's killer.

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A serial rapist leaves a trail of death and destruction unchecked for years... until one victim survives.

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When Susan Woods, 30, is found beaten and drowned in her tub in America's cowboy capital, suspicion falls on her estranged husband; with a suspect's DNA in hand, detectives go back to the basics to unmask a killer cowboy living in plain sight.

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Denise is stabbed repeatedly by men robbing her store. Nick gets lost on a ski slope during a blizzard. Leonilda's ex-boyfriend takes her away by gunpoint and plans on killing her.

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Along with her best friend Liz, Brandi Hicks is abducted by a man they picked up at a video store. Joseph and Lorenzo are lost at sea during a fishing trip in Mexico. Sam and Suzanne are held hostage by a wanted killer while driving home in Arkansas.

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Four months after an Oklahoma man goes missing, divers searching for an antique Model T Ford in Claremore Lake come across a body.

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When a Texas gas store owner, Subir Chatterjee, 58, is shot inside his check cashing booth in 2002, detectives suspect his killer is someone Subir knew. With the murderer’s DNA in hand, one detective refuses to retire until the case is solved.

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Bridget is abducted by a man at gunpoint. Ryan and John are on a private plane with a friend and their friend's father when they are caught up in some bad weather. Daryl is stranded alone in the wilderness when a huge snow storm rolls in.

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