Épisodes

  • Episode 12: High-Resolution Mass Spectrometry (HRMS) in Palladium-Catalyzed Reactions
    Jan 23 2025

    Dive into the world of cutting-edge catalysis research with Dr. Roberto Silva Villatoro in this captivating episode of Concentrating on Chromatography. Hosted by David Oliva, General Manager of Organomation, this interview explores how high-resolution mass spectrometry (HRMS) is revolutionizing our understanding of palladium-catalyzed reactions. Key highlights: - Discover how HRMS detects elusive organometallic intermediates - Learn about overcoming air-sensitivity challenges in sample preparation - Explore the implications of off-cycle species in catalytic processes - Gain insights into the future of C-X and C-C bond-forming reactions Whether you're a chemistry enthusiast, a seasoned researcher, or an industry professional, this interview offers valuable insights into the intricate world of catalytic mechanisms. Join us as we uncover the potential for cleaner, more efficient chemical processes and the power of interdisciplinary collaboration in advancing scientific discovery. Don't forget to like, subscribe, and hit the notification bell to stay updated on the latest in chromatography, mass spectrometry, and sample preparation! #Catalysis #MassSpectrometry #ChemistryResearch #Chromatography #ScientificDiscovery

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    13 min
  • Episode 11: Sustainable Chemistry & Innovative Chromatography
    Jan 23 2025

    Join us for an insightful interview with Dr. Isaiah Speight, Assistant Professor at William and Mary, as he discusses his groundbreaking work in sustainable chemistry and innovative chromatography techniques. In this engaging conversation, Prof. Speight shares: - His research focus on sustainable chemistry from synthesis, financial, and educational perspectives - The importance of NOBCChE (National Organization for the Professional Advancement of Black Chemists and Chemical Engineers) - How HPLC and flash chromatography enable synthetic chemistry - The advantages of automated flash chromatography systems - Method development processes for new compounds and reactions - Exciting ongoing projects, including 3D-printed mechanochemical reaction vessels and mercury-centered metal-organic frameworks Discover how Prof. Speight's lab is pushing the boundaries of sustainable chemistry while training the next generation of undergraduate researchers. This interview offers valuable insights for chemists, students, and anyone interested in the future of sustainable scientific practices. #SustainableChemistry #Chromatography #STEM #NOBCChE #ResearchInnovation

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    22 min
  • Episode 10: Analyzing PFAS and Androgens through HPLC and Radiochromatography
    Jan 16 2025

    Dive into the world of environmental toxicology with Andrea Andress Huacachino, a PhD student at the University of Pennsylvania. In this fascinating interview, Andrea discusses her groundbreaking research on PFAS (per- and polyfluoroalkyl substances) and their impact on androgen regulation. Learn about: - The novel finding of PFOA's effect on pre-receptor androgen regulation - Innovative use of radio chromatography in hormone analysis - Challenges in developing HPLC methods for androgen separation - The broader implications of androgen dysregulation on human health Discover how environmental pollutants affect hormones in all humans and why this research matters for everyone. Perfect for science enthusiasts, students, and anyone interested in the intersection of chemistry and human health. #EnvironmentalToxicology #PFAS #Androgens #ChemistryResearch #ScienceInterview

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    24 min
  • Episode 9: Unraveling Coffee's Potato Taste Defect Insights from 2D Gas Chromatography
    Jan 13 2025

    Dr. Caitlin Cain discusses her groundbreaking research on potato taste defect (PTD) in coffee using comprehensive two-dimensional gas chromatography (GC×GC). Learn how this advanced technique revealed 359 class-distinguishing analytes related to PTD, providing unprecedented insights into this complex flavor issue. Key points covered: - Advantages of GC×GC over traditional one-dimensional GC for complex samples - Optimization of headspace solid-phase microextraction for coffee volatile analysis - Surprising findings from the comprehensive volatile profile of PTD-affected coffee - Implications for coffee farmers and the industry in combating PTD Discover how this research is advancing our understanding of coffee chemistry and potentially improving coffee quality worldwide. #CoffeeScience #Chromatography #AnalyticalChemistry #FoodChemistry

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    19 min
  • Episode 8: Natural Product Discovery through Liquid Extraction Based Ambient Ionization Mass Spectrometry
    Jan 10 2025

    Dive into the cutting-edge world of natural product discovery with Jess Deng, a fourth-year PhD candidate at Queen's University. In this engaging interview, Jess discusses her groundbreaking research using ambient ionization mass spectrometry to streamline the discovery of novel fungal metabolites. Key highlights: - Learn about the liquid microjunction surface sampling probe (LMJ SSP) and its advantages - Discover how Jess is tackling the time and resource challenges in natural product research - Explore the effects of light conditions and environmental factors on fungal metabolism - Hear about Jess's exciting work at the Smithsonian Museum of Conservation From rapid screening techniques to machine learning algorithms, Jess shares insights that could reshape the future of pharmaceutical research and biofuel production. Don't miss this fascinating look into the intersection of mass spectrometry, fungal biology, and drug discovery! #MassSpectrometry #NaturalProductDiscovery #FungalMetabolites #PhDResearch #ASMS2024

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    17 min
  • Episode 7: Antibiotic Drug Discovery UPLC Analysis and Challenges in Medicinal Chemistry
    Jan 4 2025

    In this insightful interview, Medicinal Chemist Schyler Odum discusses his work in antibiotic drug discovery and the critical role of Ultra-High Performance Liquid Chromatography (UPLC) in his research. Schyler, a fifth-year graduate student at UTHSC, shares his expertise on: The importance of antibiotic drug discovery in academic institutions How UPLC differs from HPLC and its benefits in chemical analysis Challenges in sample preparation and potential improvements The complexities of synthesizing large molecular weight antibiotics The need for increased support and funding in antibiotic research Schyler also highlights the Gordon Research Conferences as a platform for presenting antibiotic drug discovery work. This video offers valuable insights for chemistry students, researchers, and anyone interested in the future of antibiotic development. #AntibioticResearch #MedicinalChemistry #UPLC #DrugDiscovery #GraduateResearch

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    13 min
  • Episode 6: Evaporative Sample Preparation for Chromatography
    Jan 3 2025

    Dive into the world of sample preparation with industry expert Wade Hasenour as he shares invaluable insights on rotary evaporation, centrifugal evaporation, and freeze drying. Learn about the latest advancements, challenges, and future trends in sample prep techniques for chromatography. Discover how to choose the right method for your needs, optimize your workflow, and leverage automation for better results. Whether you're a seasoned chromatographer or just starting out, this video offers essential knowledge to enhance your sample preparation skills and achieve more reliable outcomes in your research. #Chromatography #SamplePreparation #LabTechniques #ScientificResearch #massspectrometry

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    34 min
  • Episode 5: Advancing Parenteral Nutrition Analysis - UPLC-MS Method Development for Phospholipid Quantification
    Dec 26 2024

    Dive into the cutting-edge world of pharmaceutical analysis with Mark Dennis Retrato, a PhD candidate at Uppsala University. In this exclusive interview, Mark shares his groundbreaking research on developing a novel UPLC-MS method for analyzing phospholipids in total parenteral nutrition (TPN) products. Key highlights: • Innovative UPLC-MS method for phospholipid quantification • Importance of nitrogen evaporation in sample preparation • Unexpected findings in phosphatidylcholine species • Implications for quality control in pharmaceutical manufacturing • Potential impact on patient care and TPN product stability Learn how this research is pushing the boundaries of analytical chemistry and contributing to improved healthcare outcomes. Whether you're a scientist, healthcare professional, or simply curious about advancements in medical technology, this interview offers valuable insights into the future of parenteral nutrition analysis. Don't forget to like, subscribe, and hit the notification bell to stay updated on the latest developments in chromatography and mass spectrometry! #UPLCMS #ParenteralNutrition #PharmaceuticalAnalysis #Chromatography #MassSpectrometry #PhDResearch

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    22 min