This provides an in-depth exploration of Hantavirus, covering its discovery during the Korean War and identification near the Hantaan River in South Korea. It explains the virus's close relationship with specific rodent hosts and how transmission to humans occurs primarily through inhalation of aerosolized particles from rodent excreta. The piece details the two main clinical manifestations: Hantavirus Pulmonary Syndrome (HPS) in the Americas with its high mortality rate, and Hemorrhagic Fever with Renal Syndrome (HFRS) prevalent in Europe and Asia. It describes the progression from initial flu-like symptoms to potentially fatal respiratory or kidney failure, along with diagnostic challenges, treatment approaches, and prevention strategies focused on minimizing rodent contact. The article concludes by discussing the relationship between environmental changes, human expansion into wildlife habitats, and the risk of zoonotic diseases like Hantavirus.