Your brain does all kinds of strange things — and neuroscientist Heather Berlin wants to explain how it works. In this episode, she joins Hakeem to explore the mysteries of the mind: how consciousness works, how your brain constructs reality, and how you might be able to hack it to live a better life. They dive into the effects of psychedelics and meditation, and explore the future of thought in a world shaped by AI. This episode is no placebo – it really will expand your mind.

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Guest Bio:

Heather Berlin is a neuroscientist, clinical psychologist, and associate clinical professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai in New York. She is interested in how consciousness and creativity work within the brain and is also the host of NOVA’s "Your Brain" two-part special.

The universe loves making things complicated. From minerals and microbes to languages and societies, complexity keeps showing up — but why? Astrobiologist Mike Wong and mineralogist Bob Hazen think we’re missing a law of nature to explain this phenomenon. Hakeem sits down with them to understand – and kick the tires on – their bold new idea: what they call a Law of Increasing Functional Information. They break down how it works, why it matters, and how it could reshape our understanding of everything from life to language to the universe itself.

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Guest Bios:

Robert Hazen is a mineralogist and astrobiologist at Carnegie Science and George Mason University. His pioneering research explores the origins of life and the evolving diversity of minerals on Earth. A prolific author and public communicator, Hazen has written widely on science, complexity, and the deep connections between the physical and biological worlds.

Mike Wong is an astrobiologist and planetary scientist at Carnegie Science whose work focuses on how life begins and evolves on worlds like our own. He is also a science communicator, hosting the podcast Strange New Worlds, where he brings complex cosmic ideas to broad audiences. Wong’s research and outreach bridge cutting-edge science with big-picture questions about life in the universe.

Their new book Time's Second Arrow: Evolution, Order, and a New Law of Nature will be available in February 2026.

Black holes get a bad rap. They’ve been cast as the monsters of the cosmos — gobbling up stars and stretching anything that gets too close into cosmic spaghetti. But Black Hole expert Janna Levin has spent her career decoding these mysterious objects, and she thinks they’re just misunderstood. In this episode, she dives into the strange physics of black holes: what they are, what they sound like, what happens if you fall into one, and how there’s a lighter side to every black hole. Janna shares why black holes might not be the end of everything — but the beginning of something even weirder.

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Guest Bio:

Janna Levin is a professor of physics and astronomy at Barnard College of Columbia University, where she explores the profound mysteries of black holes, cosmology, and the nature of the universe. She is also the founding scientific director of Pioneer Works, a nonprofit cultural center in Brooklyn that fosters collaboration across science, art, and education. An award-winning author and renowned science communicator, Levin has written several acclaimed books, including Black Hole Blues and Other Songs from Outer Space, and has spent her career making the strange and beautiful realities of the cosmos accessible to a wide audience. She is host of NOVA’s two-part special Black Hole Apocalypse.

In a world flooded with fake images, manipulated videos, and AI-generated voices, how do we know what’s real anymore? Hany Farid has made it his mission to find out. A leading voice in AI research and digital forensics, Hany works to authenticate digital media and expose the fakes. In this episode, Hakeem and Hany dive into how we got here. How does AI really work? How are deepfakes detected? And what does the future hold for truth in the digital age? Plus, Hakeem puts Hany to the test: can he tell the difference between real and AI-generated headlines? And can Hakeem tell a deepfake version of Hany from the real thing?

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Guest Bio:

Hany Farid is a Professor at the UC Berkeley School of Information. In addition to teaching at UC Berkeley, Hany is Chief Science Officer at GetReal Security, a company that focuses on the authentication of digital media. His research focuses on digital forensics, forensic science, misinformation, image analysis, and human perception. He has published dozens of papers on how humans relate to AI and technology.

What do fossilized leaves, an asteroid, and Florida sinkholes have in common? Dr. Kirk Johnson oversees one of the largest natural history collections on the planet, and he has the answers. He’s spent his career digging into the story of life on Earth across millions (and billions) of years. In this episode, Hakeem and Kirk explore the science of “deep time,” how fossils actually form, and the surprising origins of Earth’s oceans. Plus, Kirk shares some hot tips on fossil hunting and how to count the number of leaves on a tree … because you never know when you might need these skills.

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Guest Bio:

Dr. Kirk Johnson is Sant Director at the Smithsonian Institution, National Museum of Natural History, home to one of the largest natural history collections in the world. A paleobotanist by training, his research explores ancient climates and extinct ecosystems through the study of fossil plants. He has authored more than a dozen books on paleontology and natural history and has traveled extensively in search of fossils on every continent. As a science communicator, Dr. Johnson has brought the natural world to millions through hosting acclaimed NOVA documentaries such as Polar Extremes and Making North America, blending deep scientific expertise with an engaging, accessible storytelling style.

What happens when brilliant minds collide? In Particles of Thought, astrophysicist Hakeem Oluseyi is obsessed with understanding not just what the world's greatest scientists know, but how they think. From quantum mechanics clashing with general relativity to fossil memories written in ancient rocks, each conversation captures those electrifying moments when curiosity sparks new understanding. Join Hakeem as he explores the downright bizarre, the subatomic, and the furthest reaches of the universe through the minds that dare to question everything.

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For tens of thousands of years, humans have pondered eternal questions like “How does our world even exist?” and “Where did we come from?” Now, more than ever, scientists are finding answers within the Big Bang theory. About 13.8 billion years ago, in a fraction of a fraction of a second, the universe expanded into being. The event, astronomers believe, was less of an explosion than a transformation of energy into matter: As this so-called inflation slowed, it gave way to matter, radiation, and all we know today. But more questions loom.

To learn how scientists came up with the Big Bang theory, Dr. Alok Patel hears from a physicist and a cosmologist about the forces that shaped our early universe and the tools researchers use to peer back in time. And, he learns what scientists’ understanding of the universe’s origins can tell us about its ultimate end.

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Black holes: they’re dense, elusive, light-absorbing pockets of spacetime that are critical to our understanding of the universe. But black holes are difficult to peer into, so there’s a lot scientists still don’t know. This leaves some room for science fiction to take over. Tall tales of galactic adventure may pair well with popcorn, but they also blur the lines between fact and fiction. To explore what humanity knows—and what we think we know—about black holes, Dr. Alok Patel and a theoretical cosmologist journey to Earth’s closest black hole: the Milky Way’s own Sagittarius A*, approximately 26,000 light-years away. (Don’t worry; no scientists or science nerds were harmed in the making of this episode.)

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