Épisodes

  • Inside the Clean Room - Safely Handling Cell & Gene Therapies
    Oct 14 2025
    From CAR-T therapies to viral vectors, cell and gene treatments are redefining the boundaries of pharmacy practice—but with innovation comes complexity. Host Carolyn Liptak welcomes Dr. Mark Wiencek, Principal Microbiologist with the Technical Services Group at Contec, and Dr. Amanda Frick, Senior Clinical Manager of Market Intelligence at Vizient, to break down the challenges of compounding these advanced therapies. Listen in as they discuss real-world risk assessments, biosafety considerations, and how hospital pharmacies can safely manage these groundbreaking yet high-risk treatments. Guest speakers: Mark Wiencek, PhD Principal Microbiologist, Technical Services Group Contec Amanda Frick, PharmD, BCPS Senior Clinical Manager, Market Intelligence Vizient Host: Carolyn Liptak, MBA, RPh Pharmacy Executive Director Vizient Show Notes: [01:02-01:51] Mark shares his background and experience in microbiology [01:52-04:04] Overview of the types of cell and gene therapies (CGT) currently used in clinical practice [04:05-05:14] Which CGT therapies are most applicable to pharmacy compounding and why [05:15-10:29] Things not on the NIOSH list and the risks [10:30-12:03] Evaluating whether viral vectors can penetrate intact skin and the true occupational exposure risks [12:04-13:18] If hazards are not defined by the NIOSH list, how should these CGT hazards be classified [13:19-15:03] Determining the safest environment for compounding CGT therapies [15:04-20:14] Best practices for decontamination, disinfection, and viral vector handling [20:15-20:59] Do you need a dedicated biosafety cabinet for CGT therapies [21:00-22:55] Recommended resources for further learning Links | Resources: Blind and colleagues (Nationwide): Click hereWang and colleagues (Stanford): Click hereCONTEC HEALTHCARE WEBINAR Using Bugs as Drugs: Compounding Viral Vectors in Cell & Gene Therapy for Hospital Pharmacies, Mark Wiencek, May 13, 2025: Click hereBlind, J.E., Ghosh, S., Niese, T.D., Gardner, J.C., Stack-Simone, S., Dean, A. and Washam, M., 2024. A comprehensive literature scoping review of infection prevention and control methods for viral-mediated gene therapies. Antimicrobial Stewardship & Healthcare Epidemiology, 4(1), p.e15. Click hereDeramoudt, L., Pinturaud, M., Bouquet, P., Goffard, A., Simon, N. and Odou, P., 2024. Method for the detection and quantification of viral contamination during the preparation of gene therapy drugs in a hospital pharmacy. Occupational and Environmental Medicine, 81(12), pp.615-621. Click hereKorte, J., Mienert, J., Hennigs, J.K. and Körbelin, J., 2021. Inactivation of adeno-associated viral vectors by oxidant-based disinfectants. Human Gene Therapy, 32(13-14), pp.771-781. Click here (abstract only; full article available for purchase)Martino, J.G., McConnell, K., Greathouse, L., Rosario, B.D. and Jaskowiak, J.M., 2024. Cellular therapy site-preparedness: Inpatient pharmacy implementation at a large academic medical center. Journal of Oncology Pharmacy Practice, 30(8), pp.1442-1449. Click herePenzien, C., 2023. Safe handling of BioSafety drugs and live virus vaccines. Pharm Purch Prod, 20(4), p.12. Click herePetrich, J., Marchese, D., Jenkins, C., Storey, M. and Blind, J., 2020. Gene replacement therapy: a primer for the health-system pharmacist. Journal of Pharmacy Practice, 33(6), pp.846-855. Click hereWang, A., Ngo, Z., Yu, S.J. and MacDonald, E.A., 2025. Implementing standard practices in the safe handling of gene therapy and biohazardous drugs in a health-system setting. American Journal of Health-System Pharmacy, p.zxaf026. Click here VerifiedRx Listener Feedback Survey: We would love to hear from you - Please click here Subscribe Today! Apple Podcasts Spotify YouTube RSS Feed
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    24 min
  • Tapping into NTAP
    Sep 30 2025

    New data from the summer Vizient Spend Management Outlook show that in the inpatient space, high-cost drugs, especially CAR-T treatments like Yescarta and Breyanzi are major drivers of drug spend. To help offset these costs, certain therapies may qualify for additional reimbursement through the New Technology Add-On payment (NTAP), a program that supports innovations that substantially improve care for Medicare beneficiaries. Carolyn Liptak, Pharmacy Executive Director at the Vizient Center for Pharmacy Practice Excellence joins host Stacy Lauderdale, Associate Vice President of Evidence-Based Medicine and Drug Information at Vizient to cover the purpose of this add-on payment, the criteria necessary for drugs to qualify and strategies to capture its full value.

    Guest Speaker:

    Carolyn Liptak, MBA, RPh Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence

    Host: Stacy Lauderdale, PharmD, BCP  Associate Vice President Vizient Center for Pharmacy Practice Excellence  Verified Rx Host

    Show Notes:

    [01:02-03:38] Overview of NTAP and why CMS created the program

    [03:39-05:02] How DRG recalibration depends on broad adoption

    [05:03-07:17] Criteria for medications to quality for NTAP status

    [07:18-08:24] Who determines whether a therapy represents substantial clinical improvement

    [08:25-10:05] The value NTAP provides to hospitals

    [10:06-11:51] How to locate products that are eligible for NTAP

    [11:52-16:22] Best practices to ensure that NTAP payment is captured when the drug is used

    [16:23-17:22] Resources for additional information

    Links | Resources:

    • Payment Updates: Preparing for 2026 - On Demand
    • New Medical Services and New Technologies
    • FY 2026 IPPS Final Rule Home Page
    • MAC Implementation File 8 (ZIP) – FY 2026 New Technology Add-on Payment
    • CMS Web Pricer

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    18 min
  • GLN Changes You Can’t Ignore
    Sep 16 2025

    As the Drug Supply Chain Security Act dispenser exemption period winds down, the Vizient Standards implementation team announced an important change to the Vizient Global Location Number (GLN) Management program. The data standards team will inactivate unmanaged GLNs, which will impact pharmacies and other providers who are not currently managing their Vizient assigned GLNs. Two experts leading that conversation, Carl Henshaw, Senior Director, Data Operations, Enterprise Information and Data Management, and Dawn Burtram, Lead Analyst, Standards Implementation at Vizient join host Carolyn Liptak, Pharmacy Executive Director in the Center for Pharmacy Practice Excellence at Vizient to discuss implications.

    Guest speakers:

    Dawn Bertram, MBA

    Lead Analyst Standards Implementation

    Vizient

    Carl Henshaw

    Senior Director, Data Operations, Enterprise Information and Data Management

    Vizient

    Host: 

    Carolyn Liptak, MBA, BS Pharm

    Show Notes:

    [01:08-01:59] Dawn and Carl’s background

    [02:00-02:41] What exactly is a GLN and what does it mean to be self-managed

    [02:42-07:26] Who creates and maintains GLNs in this data hub and the three different GLN products

    [07:27-08:51] How to determine who actually enumerated the GLNs

    [08:52-10:20] Educating and preparing providers for the DSCSA compliance deadline

    [10:21-12:37] The recent decision to inactivate unmanaged GNS and why it's essential to maintaining the accuracy and reliability of GLN data

    [12:38-15:05] What it means to participate in our program and who's eligible to participate

    [15:06-17:51] Why the deadline of November 15th matters

    Links | Resources:

    Vizient GLN Learning Center

    GLN Management Process Education Session (E-Learning)

    VGMP Application

    GS1 What is a GLN and How Do I Get One? 

    Drug Supply Chain Security Act

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    18 min
  • Inside the New Joint Commission Manual
    Aug 26 2025

    The Joint Commission’s updated accreditation manual is designed to simplify requirements, enhance clarity, and better support healthcare organizations in survey preparation. In this episode of VerifiedRx, host Carolyn Liptak is joined by Dr. Robert Campbell of the Joint Commission and Diana Scott of Vizient to unpack the most significant changes. From the shift to National Performance Goals and medication safety priorities to the latest challenges in compounding, labeling, and hazardous drug handling, the conversation highlights practical insights to help pharmacy leaders stay compliant and survey-ready.

    Guest speakers:

    Robert Campbell, PharmD, BCSCP

    Sr. Director, Standards Interpretation, Accreditation Decision Management,Medication Safety Division of Accreditation and Certification Operations

    Joint Commission

    Diana Scott, MHA, RN, CPHQ

    Principal, Regulatory and Accreditation Services

    Vizient

    Host:

    Carolyn Liptak, , BS Pharm, MBA 

    Vizient

    Show Notes:

    [01:16-01:51] Diana and Robert Backgrounds

    [01:52-02:43] Changes made to the hospital and critical access hospital manuals

    [02:44-03:09] Changes to the chapters themselves

    [03:10-04:08] National Performance Goals and elaborate on those that are relevant to medication safety and pharmacy services

    [04:09-05:15] The top medication management challenges

    [05:16-06:29] Pain management not being aligned and titration orders

    [06:30-06:56] Insufficient communication between pharmacists, prescribers and nurses when it comes to medication orders

    [06:57-08:02] Themes around labeling requirements for stored medications

    [08:03-08:46] Anything different in removing expired meds from patient care areas and in the pharmacy this area than previous years

    [08:47-10:58] Issues related to storing meds specifically per the package insert

    [10:59-11:55] Common issues seen inside the pharmacy regarding sterile compounding, noncompliance include hand hygiene, garbing, PPE, and cleaning and disinfecting

    [11:56-13:12] More specifics in those area the physical environment and facility cleanliness along with cleaning and disinfection practices

    [13:13-14:55] Explaination of how joint Commission defines and evaluates immediate use compounding

    [14:56-16:09] The minimum required elements for immediate use compounding competency

    [16:10-17:12] Compounding competencies besides immediate use

    [17:13-17:54] Expectations for environmental services training

    [17:55- 20:14] Concerns around hazardous drugs

    [20:15- 21:14] Additional information

    Links | Resources:

    Joint Commission: THE NEW STANDARD: Accreditation 360

    For Members: On-Demand webinar and CE information

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    22 min
  • Partners in Prevention: A Unified Approach to Drug Diversion
    Aug 12 2025

    Drug diversion threatens patient and staff safety—and preventing it requires a coordinated, multidisciplinary approach. In this episode, Dr. Ruth Igwegbe and Shealee Mitchell of JPS Health Network join host Carolyn Liptak to share how their organization transformed a fragmented diversion process into a high-functioning, collaborative program. From building trust with frontline teams to using AI software and proactive data monitoring, Ruth and Shealee highlight how culture, consistency, and communication are essential to effective diversion prevention. Tune in for actionable strategies that elevate both patient safety and professional accountability.

    Guest speakers:

    Dr. Ruth Igwegbe PharmD, MBA,

    Pharmacy medication safety officer

    JPS Health Network

    Shealee Mitchell, BS, RN, MJur

    Pharmacy medication safety officer

    JPS Health Network

    Host:

    Carolyn Liptak, BS Pharm, MBA 

    Vizient

    Show Notes:

    [01:02-02:32] Ruth and Shealee Backgrounds

    [02:33-04:46] Background on diversion detection and prevention program at JPS

    [04:47-06:55] Shealee's clinical background and how it shaped how she works with teams across the organization

    [06:56-09:20] How the JPS diversion response team evolved

    [09:21-13:55] Advice to our listeners to strengthen their own diversion prevention programs

    [13:56-16:03] Where our listeners should go to get more information about drug diversion prevention and detection programs

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    17 min
  • Beyond Humira: What’s Driving Drug Spend Now?
    Jul 30 2025

    The Vizient Summer 2025 Spend Management Outlook (SMO) provides an integrated perspective on trends, factors and future expenses providers will face across the various dimensions of healthcare. In this episode, Dr. Carina Dolan and Dr. Jeni Hayes join host Carolyn Liptak to discuss pharmacy insights from the SMO including declining drug price inflation and how autoimmune conditions have surpassed oncology in total pharmacy costs. They also touch on pediatric spend drivers, biosimilar competition, and the impact of novel therapies. Tune in to VerifiedRx for practical insights to help pharmacy leaders plan for what’s ahead.

    Guest speakers:

    Carina Dolan, Pharm. D., MS Pharm, BCOP Associate Vice President, Clinical Oncology, Pharmacoeconomics and Market Insights Vizient Jeni Hayes, PharmD, MS Pharm, BCPS Senior Clinical Manager, Market Intelligence Vizient  Host:  Carolyn Liptak, BS Pharm, MBA VerifiedRx Host

    Show Notes:

    [01:13-02:41] Key pharmacy trends emerging from the Summer SMO

    [02:42-04:00] Current pharmacy trends

    [04:01-05:55] Pharmacy spend for autoimmune conditions has exceeded that of oncology

    [05:56-07:36] Key takeaways

    [07:37-08:47] Significant trends in this latest therapeutic insights update

    [08:48-10:04] Challenges in gene and cell therapy space

    [10:05-11:33] The Therapeutic Insights webpage for pediatrics

    [11:34-13:41] Other reflections from the SMO

    [13:42-14:49] How to locate the SMO

    Links | Resources:

    Vizient Spend Management Outlook

    Vizient Therapeutic class insights

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    16 min
  • Let’s fix this: 2024 drug shortage survey results
    Jul 15 2025

    Drug shortages continue to be a significant issue in the healthcare system, affecting various aspects of patient care and imposing substantial costs on hospitals and health systems. According to Vizient's 2024 drug shortages survey, U.S. hospitals are spending approximately 20 million hours annually managing these shortages, resulting in nearly $900 million in associated labor costs. The survey highlights that 74% of facilities reported exceeding their pharmacy budgets due to drug shortages, with pediatric facilities facing particularly significant financial and labor strain.

    Kyle Hoelting, director of pharmacy supply assurance and stewardship and Nikola Markoski, director of pharmacy sourcing strategic solutions and analytics join host Katie Korte, vice president Vizient Reserve to delve into the results of Vizient’s 2024 drug shortage survey.

    Guest speakers:

    Kyle Hoelting, Pharm.D, BCPS

    Director, Pharmacy Supply Assurance & Stewardship

    Vizient Center for Pharmacy Practice Excellence

    Nikola Markoski, Pharm.D, MBA

    Director, Pharmacy Sourcing Strategic Solutions & Analytics

    Vizient

    Host:

    Katie Kortie, Pharm.D, MHA, BCPS, BCCCP

    Vice President, Strategy & Program Lead, Vizient Reserve

    Vizient

    Show Notes:

    [00:47-01:14] Kyle and Niko Backgrounds

    [01:15-05:04] What's different about this year's survey and what made 2023 a critical year in the drug shortage landscape

    [05:05-08:27] How data was collected, what did the mix of information tells us and the biggest insights or patterns that surfaced in the survey

    [08:28-12:25] What Vizient’s built or enabled that’s made a difference in this space

    [12:26-15:55] How best to prepare for and respond to shortages from an inventory perspective

    Links | Resources:

    • Beyond the Shortage: The Hidden Cost of Drug Supply Chain Disruptions
    • Drug shortage stewardship: A novel solution for an old problem
    • Vizient Key performance indicators for the management of drug shortages
    • Vizient Essential Medications List

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    16 min
  • Built to Last: Rx for Resilience
    Jun 24 2025

    We all know that clinician burnout negatively impacts the quality of patient care. That's why pharmacy residency accrediting bodies now emphasize resident well-being and professional sustainability as core components of residency training earlier in clinician careers. The American Society of Health-System Pharmacists (ASHP) Accreditation Standards for PGY1 and PGY2 Pharmacy Residencies include a formal requirement for programs to address resilience, well-being, and burnout prevention, reflecting the increasing recognition of burnout in healthcare. Joining us to talk that out are Tony Huke, Senior Pharmacy Executive Director with Vizient Pharmacy Advisory Solutions and Kendra Gage, Inpatient Clinical Pharmacist and the PGY 1 Residency Program Director at UCHealth, University of Colorado Hospital in Aurora, Colorado.

    Guest speakers:

    Tony Huke, PharmD, BCPS, FASHP

    Senior Pharmacy Executive Director

    Vizient Pharmacy Advisory Solutions

    Kendra Gage, PharmD, BCPS

    Inpatient Clinical Pharmacist

    PGY1 Pharmacy Residency Program Director

    UCHealth

    Host:

    Kerry Schwarz, PharmD, MPH

    Senior Clinical Manager, Evidence-Based Medicine and Outcomes

    Center for Pharmacy Practice Excellence (CPPE)

    Show Notes:

    [01:11-03:25] What’s new at the national level in terms of pharmacy resident resiliency and well-being

    [03:26-03:56] The intentionality of well-being in pharmacy residency programs

    [03:57-05:12] Examples from Kendra’s program

    [05:13-06:40] Program expectations to address resilience

    [06:41-08:33] Assessment and potential metrics of resiliency programs

    [08:34-11:06] The role of pharmacy leadership and residency program directors in resiliency

    [11:07-12:34] Impact of resiliency programs so far

    Links | Resources:

    Accreditation Standards for PGY1 and PGY2 Pharmacy Residencies

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    13 min