Academic Research

Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation. Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come.

“I am opposed to heart disease and cancer the way one is opposed to sin.” With that as her battle cry, health activist and philanthropist Mary Woodard Lasker had a singular goal: saving lives by increasing medical research. Together with her husband, advertising genius Albert, they created the Lasker Foundation, bestowing the Lasker Awards. But the real increase in medical research funding occurred when Mary discovered a revolutionary source: the federal government. “I’m just a catalytic agent,” she would insist, while she tirelessly lobbied Congress and presidents alike.

Series editor Andrew Leckey and guest editor Marshall Loeb have scoured the print media and have consulted with editors of major business and general-interest publications and with the deans of several schools of journalism in order to find the 30 best business stories from the past 12 months. Among the articles selected: Ken Auletta on Herb Allen's CEO retreat, from The New Yorker; Diane Brady on Martha Stewart, from Business Week; and Steve Silberman on creating a borderless global cyber-marketplace, from Wired.

Every 69 seconds, someone is diagnosed with Alzheimer's disease. Of the top 10 killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation.