Biological Age

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

Journalist Jeff Bercovici spent extensive time with professional and Olympic athletes, coaches, and doctors to find how today's sports superstars seemed to be able to defy the limits of physical aging that inevitably sideline their competitors. Through fascinating profiles and first-person anecdotes, Bercovici illuminates the science and strategies extending the careers of elite older athletes, uncovers the latest advances in fields from nutrition to brain science to virtual reality, and offers empowering insights about how the rest of us can find peak performance at any age.

The Age of Living Machines describes some of the most exciting new developments and the scientists and engineers who helped create them. Virus-built batteries. Protein-based water filters. Cancer-detecting nanoparticles. Mind-reading bionic limbs. Computer-engineered crops. Together they highlight the promise of the technology revolution of the 21st century to overcome some of the greatest humanitarian, medical, and environmental challenges of our time.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

As recently as 11,000 years ago - "near time" to geologists - mammoths, mastodons, gomphotheres, ground sloths, giant armadillos, native camels and horses, the dire wolf, and many other large mammals roamed North America. In what has become one of science's greatest riddles, these large animals vanished in North and South America around the time humans arrived at the end of the last great ice age.

The Pleistocene is the epoch of geologic time closest to our own. It’s a time of ice ages, global migrations, and mass extinctions - of woolly rhinos, mammoths, giant ground sloths, and not least early species of Homo. It’s the world that created ours. But outside that environmental story there exists a parallel narrative that describes how our ideas about the Pleistocene have emerged.

In 2018, scientists manipulated the DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As Gods, this achievement was one many scientists have feared from the start of the genetic age. Four times in the last fifty years, geneticists, frightened by their own technology, have called a temporary halt to their experiments. They ought to be frightened.

The emerging field of evolutionary psychology remains controversial, perhaps especially among Christians. Yet according to Justin Barrett and Pamela Ebstyne King, it can be a powerful tool for understanding human nature and our distinctively human purpose. Thriving with Stone Age Minds provides an introduction to evolutionary psychology, explaining key concepts like hyper-sociality, information gathering, and self-control.

In accessible language and with periodic references to Star Trek, motorcycle daredevils, and near-classic movies of the '80s, developmental molecular biologist John Medina explores the neurological and evolutionary factors that drive teenage behavior and can affect both achievement and engagement. Then he proposes a research-supported counterattack: a bold redesign of educational practices and learning environments to deliberately develop teens' cognitive capacity to manage their emotions, plan, prioritize, and focus.

In The Synthetic Age, Christopher Preston argues that what is most startling about this coming epoch is not only how much impact humans have had but, more important, how much deliberate shaping they will start to do. Emerging technologies promise to give us the power to take over some of Nature's most basic operations. It is not just that we are exiting the Holocene and entering the Anthropocene; it is that we are leaving behind the time in which planetary change is just the unintended consequence of unbridled industrialism.

In the new essays collected here, an interdisciplinary group of scholars asks age-old questions about the nature and well-being of humans in the context of a revolutionary new biotechnology - one that has the potential to change the genetic make-up of both existing people and future generations. Welcoming listeners who study related issues and those not yet familiar with the formal study of bioethics, the authors of these essays open up a conversation about the ethics of gene editing.

Natalie Armstrong has everything: She's smart and beautiful, has the perfect boyfriend, early acceptance to college, and a loving family. But the summer she turns 17, she finally decides to ask some unanswered questions: Who are her biological parents, and why did they give her up when she was born? These questions take her on a journey from the deep woods of Maine to the streets of New York City, from the pages of old phone books and a tattered yearbook photo to the realization that she might actually meet her biological mother face-to-face.

Lee Hood did that rarest of things. He enabled scientists to see things they couldn't see before and do things they hadn't dreamed of doing. Scientists can now sequence complete human genomes in a day, setting in motion a revolution that is personalizing medicine. Hood, a son of the American West, was an unlikely candidate to transform biology. But with ferocious drive, he led a team at Caltech that developed the automated DNA sequencer, the tool that paved the way for the Human Genome Project.

By being able to receive downloaded messages from wild and domestic animals, Shawndra translates their messages for us. These animals have shared powerful messages of unity, connection and purpose, and steps that each of us are able to take to deepen the connection, find more meaning in our lives, and become the humans that the animals know we can be. You'll hear messages from 12 different animals on what they want us to know in order to live a more profoundly amazing life.

In Once and Future Giants, science writer Sharon Levy digs through the evidence surrounding Pleistocene large animal ("megafauna") extinction events worldwide, showing that understanding this history - and our part in it - is crucial for protecting the elephants, polar bears, and other great creatures at risk today. These surviving relatives of the Ice Age beasts now face an intensified replay of that great die-off, as our species usurps the planet's last wild places while driving a warming trend more extreme than any in mammalian history.

As at home with Galileo and his daughter in Florence as he is with Diderot in Enlightenment France, William and Alice James in fin-de-siècle Boston, or the latest research on the genome, Gerald Weissmann distills the lessons of history to guide us through our troubled age. His message is clear: "Experimental science is our defense-perhaps our best defense-against humbug and the Endarkenment."

James T. Bradley introduces important biological principles and the basic procedures used in biotechnology. Various ethical issues - personhood, personal identity, privacy, ethnic discrimination, distributive justice, authenticity and human nature, and the significance of mortality in the human life cycle - are presented in a clear and unbiased manner.