Biological Technology

In this book, Prusiner tells the remarkable story of his discovery of prions - infectious proteins that replicate and cause disease but surprisingly contain no genetic material - and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases.

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

The natural world teems with remarkable conversations, many beyond human hearing range. Scientists are using groundbreaking digital technologies to uncover these astonishing sounds, revealing vibrant communication among our fellow creatures across the Tree of Life. At once meditative and scientific, The Sounds of Life shares fascinating and surprising stories of nonhuman sound, interweaving insights from technological innovation and traditional knowledge.

Knowledge of the basic ideas and principles of science is fundamental to cultural literacy. But most books on science are often too obscure or too specialized to do the general listener much good.

We all make mistakes. Nobody’s perfect. Not even some of the greatest geniuses in history, as Mario Livio tells us in this marvelous story of scientific error and breakthrough. Charles Darwin, William Thomson (Lord Kelvin), Linus Pauling, Fred Hoyle, and Albert Einstein were all brilliant scientists. Each made groundbreaking contributions to his field - but each also stumbled badly. These five scientists expanded our knowledge of life on Earth, the evolution of the Earth itself, and the evolution of the universe, despite and because of their errors. As Mario Livio luminously explains, the scientific process advances through error.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

Scientists often challenge conventional wisdom and spark debates that last for generations. But no scientist has fuelled more debate than Charles Darwin. To some he is the revolutionary 'father' of evolution. To others he is the perverse 'originator' of modern eugenics. In The Darwin Myth: The Life and Lies of Charles Darwin, author Benjamin Wiker brings these conflicting identities to light.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Supertrends: 50 Things You Need to Know About the Future is about how efficient futurists work and how we can expect the world to evolve in terms of demographics, general economics, technologies, business models, resources, environment, and lifestyles. This audiobook addresses how to predict the future, what we can expect from it, and how companies and government should adapt to the accelerating change.

On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich.

Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

Jailed as a scapegoat for Stalin's famines, Vavilov had traveled over five continents, collected hundreds of thousands of seeds in an effort to outline the ancient centers of agricultural diversity. Gary Paul Nabhan weaves together Vavilov's story with his own expeditions to Earth's richest agricultural landscapes and the cultures that tend them.

Biomimicry, the science of employing nature to advance sustainable technology, is arguably one of the hottest new business concepts. At the center of this growing movement has been award-winning inventor and biomimetic entrepreneur Jay Harman.

Charles Darwin is arguably the most influential scientist of all time. His Origin of Species forever changed our concept of the world’s creation. Darwin’s revolutionary career is the perfect vehicle for historian Paul Johnson. Marked by the insightful observation, spectacular wit, and highly readable prose for which Johnson is so well regarded, Darwin brings the gentleman-scientist and his times brilliantly into focus. From Darwin’s birth into great fortune to his voyage aboard the Beagle, to the long-delayed publication of his masterpiece, Johnson delves into what made this Victorian gentleman into a visionary scientist.

Spotting a face in a crowd is so easy, you take it for granted. But how you do it is one of science's great mysteries. And vision is involved with so much of everything your brain does. Explaining how it works reveals more than just how you see. In We Know It When We See It, Harvard neuroscientist Richard Masland tackles vital questions about how the brain processes information - how it perceives, learns, and remembers - through a careful study of the inner life of the eye.

Imagine living in a world where people use their computers, drive their cars, and communicate with one another simply by thinking. In this stunning and inspiring work, Duke University neuroscientist Miguel Nicolelis shares his revolutionary insights into how the brain creates thought and the human sense of self - and how this might be augmented by machines, so that the entire universe will be within our reach.

In Life Finds a Way, biologist Andreas Wagner reveals the deep symmetry between innovation in biological evolution and human cultural creativity. Rarely is either a linear climb to perfection - instead, "progress" is typically marked by a sequence of peaks, plateaus, and pitfalls. For instance, in Picasso's 40-some iterations of Guernica, we see the same combination of small steps, incessant reshuffling, and large, almost reckless, leaps that characterize the way evolution transformed a dinosaur's grasping claw into a condor's soaring wing.

Nano Comes to Life opens a window onto the nanoscale - the infinitesimal realm of proteins and DNA where physics and cellular and molecular biology meet - and introduces listeners to the rapidly evolving nanotechnologies that are allowing us to manipulate the very building blocks of life. Sonia Contera gives an insider's perspective on this new frontier, revealing how nanotechnology enables a new kind of multidisciplinary science that is poised to give us control over our own biology, our health, and our lives.

Survival of the fittest or survival of the nicest? Since the dawn of time man has contemplated the mystery of altruism, but it was Darwin who posed the question most starkly. From the selfless ant to the stinging bee to the man laying down his life for a stranger, evolution has yielded a goodness that in theory should never be. Set against the sweeping tale of 150 years of scientific attempts to explain kindness, The Price of Altruism tells for the first time the moving story of the eccentric American genius George Price (1922-1975), as he strives to answer evolution's greatest riddle.

If you think sexism thrives only on Wall Street or Hollywood, you haven’t visited a lab, a science department, a research foundation, or a biotech firm. Rita Colwell is one of the top scientists in America: the groundbreaking microbiologist who discovered how cholera survives between epidemics and the former head of the National Science Foundation. But when she first applied for a graduate fellowship in bacteriology, she was told, “We don’t waste fellowships on women.” A lack of support from some male superiors would lead her to change her area of study six times.