Biological Technology

In this book, Prusiner tells the remarkable story of his discovery of prions - infectious proteins that replicate and cause disease but surprisingly contain no genetic material - and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases.

The natural world teems with remarkable conversations, many beyond human hearing range. Scientists are using groundbreaking digital technologies to uncover these astonishing sounds, revealing vibrant communication among our fellow creatures across the Tree of Life. At once meditative and scientific, The Sounds of Life shares fascinating and surprising stories of nonhuman sound, interweaving insights from technological innovation and traditional knowledge.

In December 1929, in a cave near Peking, a group of anthropologists and archaeologists that included a young French Jesuit priest named Pierre Teilhard de Chardin uncovered a prehuman skull. The find quickly became known around the world as Peking Man and was acclaimed as the missing link between erect hunting apes and our Cro-Magnon ancestors. It also became a provocative piece of evidence in the roiling debate over creationism versus evolution.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

Mary Anning was only 12 years old when, in 1811, she discovered the first dinosaur skeleton - of an ichthyosaur - while fossil hunting on the cliffs of Lyme Regis, England. Until Mary's incredible discovery, it was widely believed that animals did not become extinct.

Scientists often challenge conventional wisdom and spark debates that last for generations. But no scientist has fuelled more debate than Charles Darwin. To some he is the revolutionary 'father' of evolution. To others he is the perverse 'originator' of modern eugenics. In The Darwin Myth: The Life and Lies of Charles Darwin, author Benjamin Wiker brings these conflicting identities to light.

We all make mistakes. Nobody’s perfect. Not even some of the greatest geniuses in history, as Mario Livio tells us in this marvelous story of scientific error and breakthrough. Charles Darwin, William Thomson (Lord Kelvin), Linus Pauling, Fred Hoyle, and Albert Einstein were all brilliant scientists. Each made groundbreaking contributions to his field - but each also stumbled badly. These five scientists expanded our knowledge of life on Earth, the evolution of the Earth itself, and the evolution of the universe, despite and because of their errors. As Mario Livio luminously explains, the scientific process advances through error.

Charles Darwin did not deliberately set out to be the destroyer of mythical beliefs,” some of which, in his early days as a young Christian, he had previously espoused. He was a modest man who liked to avoid controversy of any kind, yet paradoxically, he was to be the cause of the greatest controversy in the history of science and religion.When Darwin embarked on the HMS Beagle in late December 1831, bound for the southern hemisphere, he could not have imagined that the experience would lead him to formulate a theory that would totally revolutionize the way in which we viewed the natural world.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Knowledge of the basic ideas and principles of science is fundamental to cultural literacy. But most books on science are often too obscure or too specialized to do the general listener much good.

Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

Jailed as a scapegoat for Stalin's famines, Vavilov had traveled over five continents, collected hundreds of thousands of seeds in an effort to outline the ancient centers of agricultural diversity. Gary Paul Nabhan weaves together Vavilov's story with his own expeditions to Earth's richest agricultural landscapes and the cultures that tend them.

Biomimicry, the science of employing nature to advance sustainable technology, is arguably one of the hottest new business concepts. At the center of this growing movement has been award-winning inventor and biomimetic entrepreneur Jay Harman.

Charles Darwin is arguably the most influential scientist of all time. His Origin of Species forever changed our concept of the world’s creation. Darwin’s revolutionary career is the perfect vehicle for historian Paul Johnson. Marked by the insightful observation, spectacular wit, and highly readable prose for which Johnson is so well regarded, Darwin brings the gentleman-scientist and his times brilliantly into focus. From Darwin’s birth into great fortune to his voyage aboard the Beagle, to the long-delayed publication of his masterpiece, Johnson delves into what made this Victorian gentleman into a visionary scientist.

On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich.

Most people know that Gregor Mendel, the Moravian monk who patiently grew his peas in a monastery garden, shaped our understanding of inheritance. But people might not know that Mendel's work was ignored in his own lifetime, even though it contained answers to the most pressing questions raised by Charles Darwin's revolutionary book, On Origrin of the Species, published only a few years earlier. Mendel's single chance of recognition failed utterly, and he died a lonely and disappointed man.

Imagine living in a world where people use their computers, drive their cars, and communicate with one another simply by thinking. In this stunning and inspiring work, Duke University neuroscientist Miguel Nicolelis shares his revolutionary insights into how the brain creates thought and the human sense of self - and how this might be augmented by machines, so that the entire universe will be within our reach.

In Life Finds a Way, biologist Andreas Wagner reveals the deep symmetry between innovation in biological evolution and human cultural creativity. Rarely is either a linear climb to perfection - instead, "progress" is typically marked by a sequence of peaks, plateaus, and pitfalls. For instance, in Picasso's 40-some iterations of Guernica, we see the same combination of small steps, incessant reshuffling, and large, almost reckless, leaps that characterize the way evolution transformed a dinosaur's grasping claw into a condor's soaring wing.

Nano Comes to Life opens a window onto the nanoscale - the infinitesimal realm of proteins and DNA where physics and cellular and molecular biology meet - and introduces listeners to the rapidly evolving nanotechnologies that are allowing us to manipulate the very building blocks of life. Sonia Contera gives an insider's perspective on this new frontier, revealing how nanotechnology enables a new kind of multidisciplinary science that is poised to give us control over our own biology, our health, and our lives.

Survival of the fittest or survival of the nicest? Since the dawn of time man has contemplated the mystery of altruism, but it was Darwin who posed the question most starkly. From the selfless ant to the stinging bee to the man laying down his life for a stranger, evolution has yielded a goodness that in theory should never be. Set against the sweeping tale of 150 years of scientific attempts to explain kindness, The Price of Altruism tells for the first time the moving story of the eccentric American genius George Price (1922-1975), as he strives to answer evolution's greatest riddle.