Biological Technology

Once relegated to the fringes of society, transhumanism (the use of technology to enhance human intellectual and physical capability) is now poised to enter our cultural mainstream. It has found adherents in Silicon Valley billionaires Ray Kurzweil and Peter Diamandis. Google has entered the picture, establishing a bio-tech subsidiary aimed at solving the problem of aging. In To Be a Machine, journalist Mark O'Connell takes a headlong dive into this burgeoning movement.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

In December 1929, in a cave near Peking, a group of anthropologists and archaeologists that included a young French Jesuit priest named Pierre Teilhard de Chardin uncovered a prehuman skull. The find quickly became known around the world as Peking Man and was acclaimed as the missing link between erect hunting apes and our Cro-Magnon ancestors. It also became a provocative piece of evidence in the roiling debate over creationism versus evolution.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

Survival of the fittest or survival of the nicest? Since the dawn of time man has contemplated the mystery of altruism, but it was Darwin who posed the question most starkly. From the selfless ant to the stinging bee to the man laying down his life for a stranger, evolution has yielded a goodness that in theory should never be. Set against the sweeping tale of 150 years of scientific attempts to explain kindness, The Price of Altruism tells for the first time the moving story of the eccentric American genius George Price (1922-1975), as he strives to answer evolution's greatest riddle.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

Scientists often challenge conventional wisdom and spark debates that last for generations. But no scientist has fuelled more debate than Charles Darwin. To some he is the revolutionary 'father' of evolution. To others he is the perverse 'originator' of modern eugenics. In The Darwin Myth: The Life and Lies of Charles Darwin, author Benjamin Wiker brings these conflicting identities to light.

Biomimicry, the science of employing nature to advance sustainable technology, is arguably one of the hottest new business concepts. At the center of this growing movement has been award-winning inventor and biomimetic entrepreneur Jay Harman.

In this book, Prusiner tells the remarkable story of his discovery of prions - infectious proteins that replicate and cause disease but surprisingly contain no genetic material - and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases.

Revealed for the first time in Racing for the Bomb, Groves played a crucial and decisive role in the planning, timing, and targeting of the Hiroshima and Nagasaki missions. Norris offers new insights into the complex and controversial questions surrounding the decision to drop the bomb in Japan and Groves' actions during World War II, which had a lasting imprint on the nuclear age and the Cold War that followed.

Charles Darwin is arguably the most influential scientist of all time. His Origin of Species forever changed our concept of the world’s creation. Darwin’s revolutionary career is the perfect vehicle for historian Paul Johnson. Marked by the insightful observation, spectacular wit, and highly readable prose for which Johnson is so well regarded, Darwin brings the gentleman-scientist and his times brilliantly into focus. From Darwin’s birth into great fortune to his voyage aboard the Beagle, to the long-delayed publication of his masterpiece, Johnson delves into what made this Victorian gentleman into a visionary scientist.

The name of Charles Darwin is known to nearly all who have had the benefit of a Western-style education. It is synonymous with the theory of evolution and due to his perspective of man as an animal, his worked ushered in a new paradigm of understanding of the physical and mental behavior of man. However, because of the immense impact of his best known theory, most know only of his work through reviews and historical reports.

Knowledge of the basic ideas and principles of science is fundamental to cultural literacy. But most books on science are often too obscure or too specialized to do the general listener much good.

Nano Comes to Life opens a window onto the nanoscale - the infinitesimal realm of proteins and DNA where physics and cellular and molecular biology meet - and introduces listeners to the rapidly evolving nanotechnologies that are allowing us to manipulate the very building blocks of life. Sonia Contera gives an insider's perspective on this new frontier, revealing how nanotechnology enables a new kind of multidisciplinary science that is poised to give us control over our own biology, our health, and our lives.

Jailed as a scapegoat for Stalin's famines, Vavilov had traveled over five continents, collected hundreds of thousands of seeds in an effort to outline the ancient centers of agricultural diversity. Gary Paul Nabhan weaves together Vavilov's story with his own expeditions to Earth's richest agricultural landscapes and the cultures that tend them.

Most people know that Gregor Mendel, the Moravian monk who patiently grew his peas in a monastery garden, shaped our understanding of inheritance. But people might not know that Mendel's work was ignored in his own lifetime, even though it contained answers to the most pressing questions raised by Charles Darwin's revolutionary book, On Origrin of the Species, published only a few years earlier. Mendel's single chance of recognition failed utterly, and he died a lonely and disappointed man.

The award-winning journalist Lisa Margonelli investigates the environmental and economic impact termites inflict on human societies in this fascinating examination of one of nature's most misunderstood insects.

Imagine living in a world where people use their computers, drive their cars, and communicate with one another simply by thinking. In this stunning and inspiring work, Duke University neuroscientist Miguel Nicolelis shares his revolutionary insights into how the brain creates thought and the human sense of self - and how this might be augmented by machines, so that the entire universe will be within our reach.

In Life Finds a Way, biologist Andreas Wagner reveals the deep symmetry between innovation in biological evolution and human cultural creativity. Rarely is either a linear climb to perfection - instead, "progress" is typically marked by a sequence of peaks, plateaus, and pitfalls. For instance, in Picasso's 40-some iterations of Guernica, we see the same combination of small steps, incessant reshuffling, and large, almost reckless, leaps that characterize the way evolution transformed a dinosaur's grasping claw into a condor's soaring wing.

If you think sexism thrives only on Wall Street or Hollywood, you haven’t visited a lab, a science department, a research foundation, or a biotech firm. Rita Colwell is one of the top scientists in America: the groundbreaking microbiologist who discovered how cholera survives between epidemics and the former head of the National Science Foundation. But when she first applied for a graduate fellowship in bacteriology, she was told, “We don’t waste fellowships on women.” A lack of support from some male superiors would lead her to change her area of study six times.