Biology Genetics

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the 20-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics.

In this groundbreaking work, evolutionary biologist Jared Diamond stunningly dismantles racially based theories of human history by revealing the environmental factors actually responsible for history's broadest patterns. It is a story that spans 13,000 years of human history, beginning when Stone Age hunter-gatherers constituted the entire human population. Guns, Germs, and Steel is a world history that really is a history of all the world's peoples, a unified narrative of human life.

Coyote America is both an environmental and a deep natural history of the coyote. It traces both the five-million-year-long biological story of an animal that has become the "wolf" in our backyards and its cultural evolution from a preeminent spot in Native American religions to the hapless foil of the Road Runner. A deeply American tale, the story of the coyote in the American West and beyond is a sort of Manifest Destiny in reverse.

Evolutionary theory has long established that humans are animals: Modern Homo sapiens are primates who share an ancestor with monkeys and other great apes. Our genome is 98 percent identical to a chimpanzee's. And yet we think of ourselves as exceptional. Are we? In this original and entertaining tour of life on Earth, Adam Rutherford explores the profound paradox of the "human animal".

Australopithecines, dinosaurs, trilobites - such fossils conjure up images of lost worlds filled with vanished organisms. But in the full history of life, ancient animals, even the trilobites, form only the half-billion-year tip of a nearly four-billion-year iceberg. Andrew Knoll explores the deep history of life from its origins on a young planet to the incredible Cambrian explosion, presenting a compelling new explanation for the emergence of biological novelty.

Humans are a puzzling species. On the one hand, we struggle to survive on our own in the wild, often failing to overcome even basic challenges, like obtaining food, building shelters, or avoiding predators. On the other hand, human groups have produced ingenious technologies, sophisticated languages, and complex institutions that have permitted us to successfully expand into a vast range of diverse environments. What has enabled us to dominate the globe, more than any other species, while remaining virtually helpless as lone individuals?

We are living through the most prosperous age in all of human history, yet we are listless, divided, and miserable. Wealth and comfort are unparalleled, but our political landscape is unmoored, and rates of suicide, lone­liness, and chronic illness continue to skyrocket. How do we explain the gap between these truths? And how should we respond? For evolutionary biologists Heather Heying and Bret Weinstein, the cause of our troubles is clear: The accelerat­ing rate of change in the modern world has outstripped the capacity of our brains and bodies to adapt.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

In this myth-busting book, Daniel Lieberman, professor of human evolutionary biology at Harvard University and a pioneering researcher on the evolution of human physical activity, tells the story of how we never evolved to exercise - to do voluntary physical activity for the sake of health. Using his own research and experiences throughout the world, Lieberman recounts without jargon how and why humans evolved to walk, run, dig, and do other necessary and rewarding physical activities while avoiding needless exertion.

Long before space travel was possible, the idea of life beyond Earth transfixed humans. In this fascinating book, astronomer Jon Willis explores the science of astrobiology and the possibility of locating other life in our own galaxy. Describing the most recent discoveries by space exploration missions, including the Kepler space telescope, the Mars Curiosity rover, and the New Horizons probe, Willis asks listeners to imagine - and choose among-five scenarios for finding life.

We human beings share 98 percent of our genes with chimpanzees. Yet humans are the dominant species on the planet - having founded civilizations and religions, developed intricate and diverse forms of communication, learned science, built cities, and created breathtaking works of art - while chimps remain animals concerned primarily with the basic necessities of survival. What is it about that two percent difference in DNA that has created such a divergence between evolutionary cousins?

This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences", leads the listener through unexplored jungles and uncharted aspects of mind to the heart of knowledge. In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.

The Greatest Show on Earth is a stunning counterattack on advocates of "Intelligent Design," explaining the evidence for evolution while exposing the absurdities of the creationist "argument". Dawkins sifts through rich layers of scientific evidence: from living examples of natural selection to clues in the fossil record; from natural clocks that mark the vast epochs wherein evolution ran its course to the intricacies of developing embryos; from plate tectonics to molecular genetics.

When Charles Darwin finished The Origin of Species, he thought that he had explained every clue but one. Though his theory could explain many facts, Darwin knew that there was a significant event in the history of life that his theory did not explain. During this event, the "Cambrian explosion", many animals suddenly appeared in the fossil record without apparent ancestors in earlier layers of rock. In Darwin's Doubt, Stephen C. Meyer tells the story of the mystery surrounding this explosion of animal life.

While plenty of entertaining books have been written about the history of alcohol and other intoxicants, none have offered a comprehensive, convincing answer to the basic question of why humans want to get high in the first place. Drunk elegantly cuts through the tangle of urban legends and anecdotal impressions that surround our notions of intoxication to provide the first rigorous, scientifically grounded explanation for our love of alcohol.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it.

Named one of the top books of 2009 by the Times Literary Supplement (London), this controversial and compelling audiobook from Dr. Stephen C. Meyer presents a convincing new case for intelligent design (ID) based on revolutionary discoveries in science and DNA. Along the way Meyer argues that Charles Darwin's theory of evolution as expounded in The Origin of Species did not, in fact, refute ID.