Genetic Disease

At the age of 27, Whitney Dafoe was forced to give up his life as a photographer who traveled the world. Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. The Puzzle Solver follows several years in which he desperately sought answers. Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition.

Cystic fibrosis is a life-altering genetic disorder, but with the right knowledge and tools, it can be better understood and managed. The Complete Guide to Cystic Fibrosis provides a clear, comprehensive overview of the disease, making it an essential resource for patients, caregivers, and healthcare professionals.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich.

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.

For Magda Newman, normal was a goal—she wanted her son Nathaniel to be able to play on the playground, swim at the beach, enjoy the moments of childhood that are often taken for granted. But Nathaniel's severe Treacher Collins syndrome—a craniofacial condition—meant that other concerns came first. Could he eat without the aid of a gastrointestinal tube? Could he hear? Would he ever be able to breathe effortlessly?

In Sleepyhead, science writer Henry Nicholls uses his own experience with chronic narcolepsy as a gateway to better understanding the cryptic, curious, and relatively uncharted world of sleep disorders. Charming, eye-opening, and deeply humanizing, Sleepyhead will help us all uncover the secrets of a good night's sleep.

A Sick Life chronicles Tionne's journey from a childhood spent in and out of the hospital, told she wouldn't live to see 30 or have children, to becoming the superstar musician who is still living out her life's dream of performing. For the first time, Tionne will tell her full life story - the diagnosis, the tumultuous rise to fame, the life in the spotlight, and the hard-fought advocacy work.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.

Alejandra Ponce, experta en nutrigenómica, nos advierte que, contrario a lo que la medicina tradicional ha dictado, no es correcto seguir recomendaciones generales: hay que buscarun plan de alimentación adecuado para tus genes, de manera que goces hoy de una vida sana y que llegues a la vejez sin enfermedades. Aunque estamos programados genéticamente para presentar ciertos padecimientos, la combinación de una nutrición personalizada y un estilo de vida saludable hace posible retrasarlos o incluso silenciarlos para siempre.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

The DNA Restart, by world-renowned neurogeneticist and New York Times best-selling author Dr. Sharon Moalem, walks you through revolutionary steps to a diet and lifestyle perfect for your individual genetic makeup. The DNA Restart plan utilizes decades of in-depth scientific research into genetics, epigenetics, nutrition, and longevity to explain the pivotal role genes play in the journey to ideal weight and health status.

Jamie Tyrone was 49 years old when she learned she had a 91% chance of getting Alzheimer's disease - by accident through genetic testing. She was shocked, but after an initial bout with depression she decided to take action rather than concede defeat. Jamie teamed up with Dr. Marwan Sabbagh, a renowned neurologist, and together they created a resource detailing not just Jamie's experience, but expert medical advice for anyone facing the disease.

Oncologist and cancer gene hunter Theo Ross delivers the first authoritative go-to for people facing a genetic predisposition for cancer. This book empowers listeners to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.

Unblinded is the true story of New Yorker Kevin Coughlin, who became blind at age 36 due to a rare genetic disorder known as Leber's hereditary optic neuropathy. Twenty years later, without medical intervention, Kevin's sight miraculously started to return. He is the only known person in the world who has experienced a spontaneous, non-medically assisted regeneration of the optic nerve. Unblinded follows Kevin's descent into darkness and his unexplained reemergence to sight.

Did you know that about 10,000 years ago humans went through a radical change in lifestyle in what is now called the Agricultural Revolution? While this event propelled humans out of the stone age and into civilization it also ultimately catapulted us into our current way of life and into the chronic disease epidemic we have today. Western medicine sees our epidemic of disease as a problem that needs to be suppressed, but our chronic disease epidemic is really a symptom.

A plane carrying a Russian biochemist crashes in the Alaskan wilderness with no survivors. A dying billionaire launches a final fight against death amid whispers of a now defunct military bioweapon: Project Snowcap. The world's leading CRISPR virologist, Doctor Elijah Vance, hovers on the edge of a breakthrough that will alter humanity at its most fundamental level.

If you or someone you love has Retinitis Pigmentosa (RP), the genetic condition that is passed down from one generation to the next, please keep reading. RP is not funny as it can be the cause of loss of vision, either in adults or children. Its effect on vision can be slow-moving or it can progress very quickly. The author has been affected for over 30 years and understands the emotional toll this condition can have on the newly diagnosed.