Genetic Disease

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.

On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life, seven years before the projected finish of the U.S. government's Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich.

Diagnosed with cystic fibrosis at the age of three, Mallory Smith grew up to be a determined, talented young woman who inspired others even as she privately raged against her illness. Despite the daily challenges of endless medical treatments and a deep understanding that she’d never lead a normal life, Mallory was determined to “Live Happy,” a mantra she followed until her death.

In Sleepyhead, science writer Henry Nicholls uses his own experience with chronic narcolepsy as a gateway to better understanding the cryptic, curious, and relatively uncharted world of sleep disorders. Charming, eye-opening, and deeply humanizing, Sleepyhead will help us all uncover the secrets of a good night's sleep.

At the age of 27, Whitney Dafoe was forced to give up his life as a photographer who traveled the world. Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. The Puzzle Solver follows several years in which he desperately sought answers. Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

Did you know that about 10,000 years ago humans went through a radical change in lifestyle in what is now called the Agricultural Revolution? While this event propelled humans out of the stone age and into civilization it also ultimately catapulted us into our current way of life and into the chronic disease epidemic we have today. Western medicine sees our epidemic of disease as a problem that needs to be suppressed, but our chronic disease epidemic is really a symptom.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

This audiobook contains proven steps and strategies to understand gout and its effect and how to cure it. We will talk about its symptoms, causes, and its effects. We will also talk about its association with other medical conditions. At the end of the book, we will talk about how you can treat gout symptoms and how to manage an attack and also prevention of further uric acid build up in the body. So let us start learning.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.

Jamie Tyrone was 49 years old when she learned she had a 91% chance of getting Alzheimer's disease - by accident through genetic testing. She was shocked, but after an initial bout with depression she decided to take action rather than concede defeat. Jamie teamed up with Dr. Marwan Sabbagh, a renowned neurologist, and together they created a resource detailing not just Jamie's experience, but expert medical advice for anyone facing the disease.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

In Mercies in Disguise, acclaimed New York Times reporter and best-selling author Gina Kolata tells the story of the Baxleys, an upstanding family in small-town South Carolina. Many of them were doctors, but still, they are struck down by an inscrutable illness. Finally they discover the cause of the disease after a remarkable sequence of providential events. Meanwhile science, progressing for 50 years along a parallel track, handed the Baxleys a question - not a cure but a blood test that would reveal who had the gene for the disease.

Renowned regenerative and restorative sports-medicine doctor Guarav Goswami, MD, provides advanced, minimally invasive (non-surgical) treatments to help his patients get back to peak performance levels - no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of stem cell therapy.

Unblinded is the true story of New Yorker Kevin Coughlin, who became blind at age 36 due to a rare genetic disorder known as Leber's hereditary optic neuropathy. Twenty years later, without medical intervention, Kevin's sight miraculously started to return. He is the only known person in the world who has experienced a spontaneous, non-medically assisted regeneration of the optic nerve. Unblinded follows Kevin's descent into darkness and his unexplained reemergence to sight.

If you or someone you love has Retinitis Pigmentosa (RP), the genetic condition that is passed down from one generation to the next, please keep reading. RP is not funny as it can be the cause of loss of vision, either in adults or children. Its effect on vision can be slow-moving or it can progress very quickly. The author has been affected for over 30 years and understands the emotional toll this condition can have on the newly diagnosed.

19世紀後半にメンデルが発見した遺伝の法則とダーウィンの進化論が出会い、遺伝学は歩み始めた。そして今、人類はゲノム編集の時代を迎えている。遺伝子が握る人類の運命とは？　ピュリッツァー賞受賞の医学者が自らの家系に潜む精神疾患の悲劇を織り交ぜながら、圧倒的なストーリーテリングで紡ぐ遺伝子全史

2000年代初頭、人間の全遺伝情報=ヒトゲノムがついに解読された。その後まもなく、山中伸弥らがiPS細胞(人工多能性幹細胞)の作製に成功。そして今、ジェニファー・ダウドナらが開発した新技術「CRISPR-Cas9」により、人類は「ゲノム編集」の時代を迎えている。自らの設計図を望み通りに書き換えられるようになったとき、人間の条件はどう変わるのか? 科学と倫理のせめぎ合いを圧倒的なストーリーテリングで描く傑作。

Eating disorders are one of the most common but elusive conditions to treat in all of Psychiatry. While current treatments do help some patients with eating disorders, many individuals receive little to no benefit from treatment options, leading to a lifelong struggle with anxiety around eating and body image.