Genetic History

Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

Our species has amassed unprecedented knowledge of nature, which we have tried to use to seize control of life and bend the planet to our will. In A Natural History of the Future, biologist Rob Dunn argues that such efforts are futile. We may see ourselves as life’s overlords, but we are instead at its mercy. In the evolution of antibiotic resistance, the power of natural selection to create biodiversity, and even the surprising life of the London Underground, Dunn finds laws of life that no human activity can annul.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

Lately, the most passionate advocates of the theory of evolution seem to present it as bad news. Scientists such as Richard Dawkins, Lawrence Krauss, and Sam Harris tell us that our most intimate actions, thoughts, and values are mere byproducts of thousands of generations of mindless adaptation. We are just one species among multitudes and therefore no more significant than any other living creature. Now comes Brown University biologist Kenneth R. Miller to make the case that this view betrays a gross misunderstanding of evolution.

The Voyage of the Beagle - or, to give it its full title, Journal of researches into the Natural History and Geology of the Countries visited during the Voyage round the World of H.M.S. Beagle under command of Captain FitzRoy, R.N. - is much more than merely an account of Darwin's scientific observations in his 1831 - 36 travels across the globe: it is fine travel writing in its own right.

Control is a book about what geneticist Adam Rutherford calls “a defining idea of the twentieth century.” Inspired by Darwin’s ideas about evolution, eugenics arose in Victorian England as a theory for improving the British population, and quickly spread to America. With disarming wit and scientific precision, Rutherford explains why eugenics still figures prominently in the twenty-first century, despite its genocidal past. And he confronts insidious recurring questions, revealing the intellectual bankruptcy of the idea, and the scientific impossibility of its realization.

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.

"It's the animal in us," we often hear when we've been bad. But why not when we're good? Primates and Philosophers tackles this question by exploring the biological foundations of one of humanity's most valued traits: morality.In this provocative book, primatologist Frans de Waal argues that modern-day evolutionary biology takes far too dim a view of the natural world, emphasizing our "selfish" genes.

In this provocative history of contemporary debates over evolution, veteran journalist Tom Bethell depicts Darwin's theory as a 19th-century idea past its prime, propped up by logical fallacies, bogus claims, and empirical evidence that is all but disintegrating under an onslaught of new scientific discoveries. Bethell presents a concise yet wide-ranging tour of the flash points of modern evolutionary theory. Bethell's account is enriched by his own personal encounters with of some of our era's leading scientists and thinkers.

In September 1838, a young Englishman named Charles Darwin hit upon the idea that "natural selection" among competing individuals would lead to wondrous adaptations and species diversity. Twenty-one years passed between that epiphany and publication of On the Origin of Species. The human drama and scientific controversy of that time constitute a fascinating, tangled tale that illuminates this cautious naturalist who sparked an intellectual revolution.

Just in the last three years a flood of new scientific findings, driven by revelations discovered in the human genome, has provided compelling new answers to many long-standing mysteries about our most ancient ancestors, the people who first evolved in Africa and then went on to colonize the whole world. Nicholas Wade weaves this host of news-making findings together for the first time into an intriguing new history of the human story before the dawn of civilization.

When Bernd Heinrich decided to write a memoir of his ultramarathon running experience, he realized that the preparation for the race was as important, if not more so, than the race itself. In Why We Run, Heinrich considers the flight endurance of birds, the antelope's running prowess and limitations, and the ultra-endurance of camels to understand how human physiology can or cannot replicate these adaptations. Heinrich offers an original and provocative work combining the rigors of science with the passion of running.

Just over 125,000 years ago, humanity was going extinct until a dramatic shift occurred—Homo sapiens started tracking the tides in order to eat the nearby oysters. Before long, they’d pulled themselves back from the brink of extinction. The human brain, and its evolutionary journey, is unlike anything else in history. In A History of the Human Brain, Bret Stetka takes listeners through that far-reaching journey. He also tackles the question of where the brain will take us next, exploring the burgeoning con­cepts of epigenetics and new technologies like CRISPR.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

How four tools enabled humanity to control its destiny What enabled us to go from simple stone tools to smartphones? How did bands of hunter-gatherers evolve into multinational empires? Listeners of Sapiens will say a cognitive revolution - a dramatic evolutionary change that altered our brains, turning primitive humans into modern ones - caused a cultural explosion. In Transcendence, Gaia Vince argues instead that modern humans are the product of a nuanced coevolution of our genes, environment, and culture that goes back into deep time.

Disorder and chaos ravage London when thousands are contaminated by the accidental discharge of an experimental bio-weapon. The disease robs its hosts of rational thought, giving them a singular desire - find more living flesh to infect. Cut off from information and senior leadership, one squadron of soldiers under the command of their senior NCO, Sergeant Major Johnson, finds itself forced to operate independently until the remnants of military and government command re-establish themselves safely at sea in the English Channel.

With stories that entertain as much as they inform, renowned evolutionist David Sloan Wilson outlines the basic principles of evolution and shows how, when properly understood, they can illuminate the length and breadth of creation, from the origin of life to the nature of religion.

More than any other modern scientists, Stephen Jay Gould has opened up to millions the wonders of evolutionary biology. His genius as an essayist lies in his unmatched ability to use his knowledge of the world, including popular culture, to illuminate the realm of science.

From the very beginning, life on Earth has been defined by war. Today, those first wars continue to be fought around and literally inside us, influencing our individual behavior and that of civilization as a whole. War between populations - whether between different species or between rival groups of humans - is seen as an inevitable part of the evolutionary process. The popular concept of "the survival of the fittest" explains and often excuses these actions.