Genetic History

Tucked away in Siberia, there are furry, four-legged creatures with wagging tails and floppy ears that are as docile and friendly as any lapdog. But, despite appearances, these are not dogs - they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken - imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time.

Without our domesticated plants and animals, human civilization as we know it would not exist. We would still be living at subsistence level as hunter-gatherers if not for domestication. It is no accident that the cradle of civilization - the Middle East - is where sheep, goats, pigs, cattle, and cats commenced their fatefully intimate associations with humans.

High in the Canadian Rockies is a small limestone quarry formed 530 million years ago called the Burgess Shale. It holds the remains of an ancient sea where dozens of strange creatures lived—a forgotten corner of evolution preserved in awesome detail. In this book, Stephen Jay Gould explores what the Burgess Shale tells us about evolution and the nature of history.

The Very Best of Charles Darwin comprises On the Origin of Species and The Voyage of the Beagle. The first introduced the theory that populations evolve over the course of generations through a process of natural selection. The evidence was gathered on the Beagle expedition in the 1830s, recounted in The Voyage of the Beagle, which is both a travel memoir and a scientific field journal of anthropological, biological, and geological interest.

It seems likely that scientists will someday discover how life can emerge on habitable planets like the early Earth and Mars. In Origin of Life: What Everyone Needs to Know, David W. Deamer has written a comprehensive guide to the origin of life that is organized in three sections.

Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

Our species has amassed unprecedented knowledge of nature, which we have tried to use to seize control of life and bend the planet to our will. In A Natural History of the Future, biologist Rob Dunn argues that such efforts are futile. We may see ourselves as life’s overlords, but we are instead at its mercy. In the evolution of antibiotic resistance, the power of natural selection to create biodiversity, and even the surprising life of the London Underground, Dunn finds laws of life that no human activity can annul.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

In its 4.5 billion–year history, life on Earth has been almost erased at least half a dozen times: shattered by asteroid impacts, entombed in ice, smothered by methane, and torn apart by unfathomably powerful megavolcanoes. And we know that another global disaster is eventually headed our way. Can we survive it? How?

As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.
It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just
during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.
This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.
Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

Lately, the most passionate advocates of the theory of evolution seem to present it as bad news. Scientists such as Richard Dawkins, Lawrence Krauss, and Sam Harris tell us that our most intimate actions, thoughts, and values are mere byproducts of thousands of generations of mindless adaptation. We are just one species among multitudes and therefore no more significant than any other living creature. Now comes Brown University biologist Kenneth R. Miller to make the case that this view betrays a gross misunderstanding of evolution.

In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.

The Voyage of the Beagle - or, to give it its full title, Journal of researches into the Natural History and Geology of the Countries visited during the Voyage round the World of H.M.S. Beagle under command of Captain FitzRoy, R.N. - is much more than merely an account of Darwin's scientific observations in his 1831 - 36 travels across the globe: it is fine travel writing in its own right.

"It's the animal in us," we often hear when we've been bad. But why not when we're good? Primates and Philosophers tackles this question by exploring the biological foundations of one of humanity's most valued traits: morality.In this provocative book, primatologist Frans de Waal argues that modern-day evolutionary biology takes far too dim a view of the natural world, emphasizing our "selfish" genes.

Just in the last three years a flood of new scientific findings, driven by revelations discovered in the human genome, has provided compelling new answers to many long-standing mysteries about our most ancient ancestors, the people who first evolved in Africa and then went on to colonize the whole world. Nicholas Wade weaves this host of news-making findings together for the first time into an intriguing new history of the human story before the dawn of civilization.

When Bernd Heinrich decided to write a memoir of his ultramarathon running experience, he realized that the preparation for the race was as important, if not more so, than the race itself. In Why We Run, Heinrich considers the flight endurance of birds, the antelope's running prowess and limitations, and the ultra-endurance of camels to understand how human physiology can or cannot replicate these adaptations. Heinrich offers an original and provocative work combining the rigors of science with the passion of running.

Discover an alternate history to the human race as the authors of Forbidden Archeology challenge one of the most fundamental components of the modern scientific world view. Michael Cremo and Richard Thompson discuss the work of researchers who, over the past 2 centuries, have found bones and artifacts showing that people like ourselves existed on earth millions of years ago.

The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator.

In his first memoir, Richard Dawkins shares a rare view into his early life, his intellectual awakening at Oxford, and his path to writing The Selfish Gene. This is an intimate memoir of the childhood and intellectual development of the evolutionary biologist and world-famous atheist and how he came to write what is widely held to be one of the most important books of the 20th century.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.