Genetic History

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

In its 4.5 billion–year history, life on Earth has been almost erased at least half a dozen times: shattered by asteroid impacts, entombed in ice, smothered by methane, and torn apart by unfathomably powerful megavolcanoes. And we know that another global disaster is eventually headed our way. Can we survive it? How?

As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.
It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just
during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.
This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.
Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

Lately, the most passionate advocates of the theory of evolution seem to present it as bad news. Scientists such as Richard Dawkins, Lawrence Krauss, and Sam Harris tell us that our most intimate actions, thoughts, and values are mere byproducts of thousands of generations of mindless adaptation. We are just one species among multitudes and therefore no more significant than any other living creature. Now comes Brown University biologist Kenneth R. Miller to make the case that this view betrays a gross misunderstanding of evolution.

Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?

Evolutionary theory in the theme that binds together these essays on such seemingly disparate topics as the feeding habits of flamingos, flowers and snails that change from male to female and sometimes back again, and the extinction from baseball of the .400 hitter.

In his provocative new book, evolutionary biologist Jerry A. Coyne lays out in clear, dispassionate detail why the toolkit of science, based on reason and empirical study, is reliable, while that of religion - including faith, dogma, and revelation - leads to incorrect, untestable, or conflicting conclusions.

Before Charles Darwin, other luminaries planted the seeds that would one day evolve into the theory that would make him famous. Author Rick Coste begins by shining a spotlight on the writers, philosophers, and scientists who planted the seeds that would blossom into the theory of evolution by natural selection, from Aristotle’s big ideas to young Mary Anning’s discovery of the first ichthyosaur skeleton. After exploring the contributions of Charles Darwin and Alfred Russel Wallace, Evolution Talk investigates the very beginnings of life itself.

On the Origin of Species is one of the most important and influential books of its time and remains one of the most significant contributions to philosophical and scientific thought. The theories Darwin sets out here had an immediate and profound impact on the literature and philosophical thought of his contemporaries and continue to provoke thought and debate today. Written for the general public of the 1850s, On the Origin of Species laid out an evolutionary view of the world which challenged contemporary beliefs about divine providence and the fixity of species.

Over a century after Darwin published the Origin of Species, Darwinian theory is in a "vibrantly healthy state," writes Stephen Jay Gould, its most engaging and illuminating exponent. Exploring the "peculiar and mysterious particulars of nature," Gould introduces the listener to some of the many and wonderful manifestations of evolutionary biology.

Just over 125,000 years ago, humanity was going extinct until a dramatic shift occurred—Homo sapiens started tracking the tides in order to eat the nearby oysters. Before long, they’d pulled themselves back from the brink of extinction. The human brain, and its evolutionary journey, is unlike anything else in history. In A History of the Human Brain, Bret Stetka takes listeners through that far-reaching journey. He also tackles the question of where the brain will take us next, exploring the burgeoning con­cepts of epigenetics and new technologies like CRISPR.

In December 1929, in a cave near Peking, a group of anthropologists and archaeologists that included a young French Jesuit priest named Pierre Teilhard de Chardin uncovered a prehuman skull. The find quickly became known around the world as Peking Man and was acclaimed as the missing link between erect hunting apes and our Cro-Magnon ancestors. It also became a provocative piece of evidence in the roiling debate over creationism versus evolution.

The story of how our ancestors made the first tentative steps towards becoming human, how we lost our fur but gained language, fire and tools, and how we strode out of Africa, invented farming and cities and ultimately created modern civilisation. Where did we come from? Where are we going? Homo sapiens is the most successful, the most widespread and the most influential species ever to walk the Earth.

Over more than 25 years of teaching and research, Christine Desdemaines-Hugon has become an unrivaled expert in the cave art and artists of the Dordogne region. In Stepping-Stones she combines her expertise in both art and archaeology to convey an intimate understanding of the "cave experience." Her keen insights communicate not only the incomparable artistic value of these works but also the near-spiritual impact of viewing them for oneself.

Our ability to think about the future is one of the most powerful tools at our disposal. In The Invention of Tomorrow, cognitive scientists Thomas Suddendorf, Jonathan Redshaw, and Adam Bulley argue that its emergence transformed humans from unremarkable primates to creatures that hold the destiny of the planet in their hands. Drawing on their own cutting-edge research, the authors break down the science of foresight, showing us where it comes from, how it works, and how it made our world.

We are now on the doorstep of a fourth change brought about by two technologies: AI and robotics. The Fourth Age provides extraordinary background information on how we got to this point, and how - rather than what - we should think about the topics we’ll soon all be facing: machine consciousness, automation, employment, creative computers, radical life extension, artificial life, AI ethics, the future of warfare, superintelligence, and the implications of extreme prosperity.

Rethinking Evolution links Darwin's early insights to the molecular realm inside living cells. This updated evolutionary synthesis provides an accessible explanation for biological complexity that cuts through the confusion surrounding evolutionary theory in a practical way. In addition to a wide-ranging survey of proposed updates to the modern synthesis, this title provides extraordinary new insights, including emergent evolutionary potential and the generative phenotype.

Dive into Evolutionary History, a mesmerizing journey through time, tracing the origins and development of all living beings. From the earliest single-celled organisms to the rise of Homo sapiens, this audiobook unravels the intricate tapestry of evolution with clarity and passion. Explore the wonders of life’s evolution across geological epochs, uncovering the secrets of adaptation, survival, and the remarkable journey of our ancestors.

The characters in Tasting the Past include a young Swiss scientist who set out to decode the DNA of every single wine grape in the world; Middle Eastern researchers who seek to discover the wines that King David drank; and a University of Pennsylvania academic who has spent decades analyzing wine remains. The science illuminates wine in ways no critic can, and demolishes some of the most sacred dogmas of the industry: well-known French grapes aren't especially noble.

James T. Costa takes listeners on a journey from Darwin's youth and travels on the HMS Beagle to Down House, his bustling home of 40 years. We accompany Darwin in his myriad pursuits against the backdrop of his enduring marriage, chronic illness, grief at the loss of three children, and joy in scientific revelation. At each chapter's end, Costa shows how we, too, can investigate the wonders of nature at work, with directions on how to re-create Darwin's experiments.

In his last book, Neil Shubin delved into the amazing connections between human anatomy—our hands, our jaws—and the structures in the fish that first took over land 375 million years ago. Now, with his trademark clarity and exuberance, he takes an even more expansive approach to the question of why we are the way we are.