Genetics Health

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

Until very recently, if you were to ask most doctors, they would tell you there were only two kinds of medicine: the quack kind, and the evidence-based kind. The former is baseless, and the latter based on the best information human effort could buy. Well, Eric Topol isn't most doctors, and he suggests you entertain the notion of a third kind of medicine, one that will make the evidence-based state-of-the-art stuff look scarcely better than an alchemist trying to animate a homunculus in a jar.

Diagnosed with cystic fibrosis at the age of three, Mallory Smith grew up to be a determined, talented young woman who inspired others even as she privately raged against her illness. Despite the daily challenges of endless medical treatments and a deep understanding that she’d never lead a normal life, Mallory was determined to “Live Happy,” a mantra she followed until her death.

“There is no good reason why human societies should not be described and explained with the same precision and success as the rest of nature.” Thus argues evolutionary psychologist Pascal Boyer in this uniquely innovative book. Integrating recent insights from evolutionary biology, genetics, psychology, economics, and other fields, Boyer offers precise models of why humans engage in social behaviors such as forming families, tribes, and nations, or creating gender roles.

If you think you are you, think again. Primate Change is a wide-ranging, polemical look at how and why the human body has changed since humankind first got up on two feet. Spanning the entirety of human history - from primate to transhuman - Vybarr Cregan-Reid's book investigates where we came from, who we are today and how modern technology will change us beyond recognition.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.

The DNA Restart, by world-renowned neurogeneticist and New York Times best-selling author Dr. Sharon Moalem, walks you through revolutionary steps to a diet and lifestyle perfect for your individual genetic makeup. The DNA Restart plan utilizes decades of in-depth scientific research into genetics, epigenetics, nutrition, and longevity to explain the pivotal role genes play in the journey to ideal weight and health status.

Do you finally want to end the pain of missing out on life-changing opportunities and experiences because of a lack of being able to get people to see things your way? Are you wondering if there is a surefire method to help you get more out of life? If you thought yes, then you've come to the right place. Persuading people doesn't have to be complicated. In fact, it's much easier than you think, and you don't have to believe me.

Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?

Homo sapiens emerged as a species about 200,000 years ago and soon—with fire, simple tools, and an egalitarian social system—we inhabited every continent. But now our infinitely elaborated tools and our highly non-egalitarian social system threaten sustainability. Many at the bottom lose the desire to live, committing suicide or succumbing to drugs, alcohol, and obesity. What is Health? explains from the bottom up—molecules to society—how we reached this point.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

Fact: Over 95% of guys fail to achieve their fitness goals. Most quit after just 1-2 months in the gym. So what's stopping you from seeing results? Simple. You're focused on all the wrong things. Fad diets, random workouts, and questionable motivations will only get you so far. To break through your plateau and see fast progress you need to re-build your fitness habit from the ground up.

With the ongoing advancement of AI and other technologies, our world is becoming increasingly intelligent. From chatbots to innovations in brain-computer interfaces to the possibility of superintelligences leading to the Singularity later this century, our reality is being transformed before our eyes. This is commonly seen as the natural result of progress, but what if there's more to it than that? What if intelligence is an inevitability, an underlying property of the universe?

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

How did humans come to be who we are? In his marvelous, eccentric, and widely lauded book Being a Beast, legal scholar, veterinary surgeon, and naturalist extraordinaire Charles Foster set out to understand the consciousness of animal species by living as a badger, otter, fox, deer, and swift. Now, he inhabits three crucial periods of human development to understand the consciousness of perhaps the strangest animal of all—the human being.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

In Sleepyhead, science writer Henry Nicholls uses his own experience with chronic narcolepsy as a gateway to better understanding the cryptic, curious, and relatively uncharted world of sleep disorders. Charming, eye-opening, and deeply humanizing, Sleepyhead will help us all uncover the secrets of a good night's sleep.

For Magda Newman, normal was a goal—she wanted her son Nathaniel to be able to play on the playground, swim at the beach, enjoy the moments of childhood that are often taken for granted. But Nathaniel's severe Treacher Collins syndrome—a craniofacial condition—meant that other concerns came first. Could he eat without the aid of a gastrointestinal tube? Could he hear? Would he ever be able to breathe effortlessly?

Between what can be learned from evolutionary psychology and cognitive science a picture emerges. In Sex, Murder, and the Meaning of Life, social psychologist Douglas Kenrick fuses these two fields to create a coherent story of human nature. In his analysis, many ingrained, apparently irrational behaviors—one-night stands, prejudice, conspicuous consumption, even art and religious devotion—are quite explicable and (when desired) avoidable.