Health Care History

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively listenable Superbugs, and the results will impact nothing less than the future of humanity.

It began with a smoke break. James Monsees and Adam Bowen were two ambitious graduate students at Stanford, and in between puffs after class they dreamed of a way to quit smoking. Their solution became the Juul, a sleek, modern device that could vaporize nicotine into a conveniently potent dosage. Time magazine reporter Jamie Ducharme follows Monsees and Bowen as they create Juul and, in the process, go from public health visionaries and Silicon Valley wunderkinds to two of the most controversial businessmen in the country.

From the 15th to the mid-19th centuries, scurvy caused more deaths at sea than storms, shipwrecks, combat, and all other diseases combined. The cure for scurvy ranks among the greatest of military successes, yet its impact on history has mostly been ignored. In this book, Stephen R. Brown delivers a lively recounting of how three determined individuals overcame the constraints of 18th century thinking to solve the greatest medical mystery of their era. Brimming with tales of ships, sailors, and bureaucracy, Brown presents a vivid picture of life aboard the ship during the age of sail.

Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 "parrot fever" pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.

In 1999, Munjed Al Muderis was a surgical resident working in Baghdad when the military police marched into the operating theatre and ordered the team to mutilate army deserters. When the head of surgery refused, he was executed. Munjed's choices were stark - comply and breach the medical oath, refuse and face death or flee. That day, Munjed's life changed forever. He escaped to Indonesia and boarded a boat to Australia.

To paraphrase the great sci-fi writer Stephen King: Kill your darlings, kill your darlings, even when it breaks your heart, kill your darlings. Translation: stay on point and mercilessly avoid side stories and anecdotes. With much respect for Mr. King, The History of Man Series is precisely that, a great deal about all those little darlings, a style of writing termed “jumping off.”

The Fourth History of Man continues with virus infections where The Third History of Man left off: hashing out those specks of genetic schmutz, covering the R-naught of those naughty infectious scoundrels. Some big hitters will be considered, from polio and the famous celebrities that had it, through 50 shades of hepatitis, rabies and the hair of the dog, and the monkey business of HIV and AIDS. Leaving viruses, we’ll delve into a study of parasites, including the parasite of all parasites, Sigourney Weaver’s alien.

Most stories of medical progress come with ready-made heroes. John Snow traced the origins of London's 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence Nightingale's contributions to the care of soldiers in the Crimean War transformed hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge.

Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

Seamus O'Mahony writes about the illusion of progress, the notion that more and more diseases can be "conquered" ad infinitum. He punctures the idiocy of consumerism, the idea that healthcare can be endlessly adapted to the wishes of individuals. He excoriates the claims of Big Science, the spending of vast sums on research follies like the Human Genome Project. And he highlights one of the most dangerous errors of industrialized medicine: an over-reliance on metrics, and a neglect of things that can't easily be measured, like compassion.

In 1866, 12 men and women and one small child were forced aboard a leaky schooner and cast away to a natural prison on the Hawaiian island of Molokai. Two weeks later, a dozen others were exiled, and then 40 more, and then 100 more. Tracked by bounty hunters and torn screaming from their families, the luckless were loaded into shipboard cattle stalls and abandoned in a lawless place where brutality held sway. Many did not have leprosy, and most of those who did were not contagious.

The Second History of Man focuses mostly on bacteria and bacterial infections as the foundation, jumping off into Darwin and evolution, gin and tonics and the discovery of the first antibiotic to treat infection (and it wasn’t penicillin), and visiting with those clever chaps who cook up drugs in the lab. We’ll call upon poets and poetry, celebrities like Frank Sinatra, the Rat Pack, and Bobby Darin, the classical music of Haydn, Mozart and Beethoven, the tragic story of World War II, Anne Frank and the Holocaust....

America’s Bitter Pill is Steven Brill’s acclaimed book on how the Affordable Care Act, or Obamacare, was written, how it is being implemented, and, most important, how it is changing—and failing to change—the rampant abuses in the healthcare industry. It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare.

The heart of many hospitals is the Neonatal Intensive Care Unit (NICU). It is a place where humanity, ethics, and science collide in dramatic and deeply personal ways as parents, doctors, and nurses grapple with sometimes unanswerable questions: When does life begin? When and how should life end? And what does it mean to be human? Nearly 20 years ago, Dr. John D. Lantos wrote The Lazarus Case, a seminal work on ethical dilemmas in neonatology. He described the NICU as “a strong, strange, powerful place”. The

Little more than 100 years ago, maps of the world still boasted white space: places where no human had ever trod. Within a few short decades the most hostile of the world's environments had all been conquered. Likewise, in the 20th century, medicine transformed human life. Doctors took what was routinely fatal and made it survivable. As modernity brought us ever more into different kinds of extremes, doctors pushed the bounds of medical advances and human endurance. Extreme exploration challenged the body in ways that only the vanguard of science could answer.

Poppy tears, opium, heroin, fentanyl: humankind has been in thrall to the ‘Milk of Paradise’ for millennia. The latex of papaver somniferum is a bringer of sleep, of pleasurable lethargy, of relief from pain - and hugely addictive. A commodity without rival, it is renewable, easy to extract, transport and refine, and subject to an insatiable global demand. No other substance in the world is as simple to produce or as profitable. It is the basis of a gargantuan industry built upon a shady underworld, but ultimately it is a farm-gate material that lives many lives ....

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

Elizabeth Blackwell believed from an early age that she was destined for a mission beyond the scope of "ordinary" womanhood. Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an MD. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.