Health Care History

It is 1919 and Elizabeth Hughes, the 11-year-old daughter of America's most-distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to 45 pounds, skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition, and fistfights.

After the unprecedented events of the COVID-19 pandemic, it may be hard to imagine a time not so long ago when deadly diseases were a routine part of life. It is harder still to fathom that the best medical thinking at that time blamed these diseases on noxious miasmas, bodily humors, and divine dyspepsia. This all began to change on a day in April 1676, when a little-known Dutch merchant described bacteria for the first time. Ending Epidemics explains how we came to understand and prevent many of our worst infectious diseases—and double average life expectancy.

The Second History of Man focuses mostly on bacteria and bacterial infections as the foundation, jumping off into Darwin and evolution, gin and tonics and the discovery of the first antibiotic to treat infection (and it wasn’t penicillin), and visiting with those clever chaps who cook up drugs in the lab. We’ll call upon poets and poetry, celebrities like Frank Sinatra, the Rat Pack, and Bobby Darin, the classical music of Haydn, Mozart and Beethoven, the tragic story of World War II, Anne Frank and the Holocaust....

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

In this astonishing book, Mark Woolhouse recounts the history of the COVID-19 pandemic through the eyes of a scientist at the very centre of the action. He explores the failures and successes of the United Kingdom’s, and the world’s, response to the virus, shows how he briefed both the British and Scottish governments on the scale of the fight ahead and candidly describes the challenges scientists faced when working with politicians.

No disease sparked as much dread in the 18th century as smallpox. The virus killed millions across the globe, carrying off one in every five victims and disfiguring survivors with tell-tale pitted scars. But one mysterious method offered hope: inoculation, the practice of piercing the skin to insert a drop of infected matter and induce a mild case of smallpox. Those inoculated safely were protected from the ‘Speckled Monster’ and stayed immune for life. Only one problem remained: convincing people to accept the treatment.

Doctors at War is a candid account of a trauma surgical team based, for a tour of duty, at a field hospital in Helmand, Afghanistan. Mark de Rond tells of the highs and lows of surgical life in hard-hitting detail, bringing to life a morally ambiguous world in which good people face impossible choices and in which routines designed to normalize experience have the unintended effect of highlighting war’s absurdity. With stories that are at once comical and tragic, de Rond captures the surreal experience of being a doctor at war.

The rest of the world had turned its back on South Africa after a controversial massacre in 1960, but seven years later, a pioneering heart surgeon was able to shine a much more positive light on the country when he performed the world's first major organ transplant. A tale about a truly inspirational man who, motivated through losing a brother to heart failure, was able to make this groundbreaking technology a reality that would go on to improve the lives of hundreds of thousands of people worldwide.

Christian W. McMillen provides a concise yet comprehensive account of pandemics throughout human history, illustrating how pandemic disease has shaped history and, at the same time, social behavior has influenced pandemic disease.

Pain is the number one reason people schedule medical appointments. Yet many people do not receive adequate relief, especially for chronic pain. Pain: The Culture and Science of Pain describes the multiple factors that contribute to the ongoing problem of unrelieved pain. There are both cultural and scientific reasons. The book discusses how various cultures and religions throughout history have downplayed the importance of relieving pain. Such biases persist today.

Rabies enjoys a fearsome and lurid reputation. Throughout the decades of spiraling growth that defined New York City from the 1840s to the 1910s, the bone-chilling cry of "Mad dog!" possessed the power to upend the ordinary routines and rhythms of urban life. In Mad Dogs and Other New Yorkers, Jessica Wang examines the history of this rare but dreaded affliction during a time of rapid urbanization.

Dr. Lange graduated from medical school in 1981, right as a new plague swept across the globe. His story became intertwined with the story of HIV. At once a physician, scientist, AIDS activist, and medical diplomat, Lange studied ways to battle HIV and prevent its spread from mother to child. Fighting the injustices of poverty, Lange advocated for better access to health care for the poor and the vulnerable. The Impatient Dr. Lange is the story of one man's struggle against a global pandemic - and the tragic attack that may have slowed down the search for a cure.

Important and provocative, The Undead examines why even with the tools of advanced technology, what we think of as life and death, consciousness and nonconsciousness, is not exactly clear - and how this problem has been further complicated by the business of organ harvesting.

Few diseases are more gruesome than typhus. Transmitted by body lice, it afflicts the dispossessed - refugees, soldiers, and ghettoized peoples - causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.

At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.

Wounded traces the journey made by a casualty from the battlefield to a hospital in Britain. It is a story told through the testimony of those who cared for him - stretcher bearers and medical officers, surgeons and chaplains, orderlies and nurses - from the aid post in the trenches to the casualty clearing station and the ambulance train back to Blighty. We feel the calloused hands of the stretcher-bearers; we see the bloody dressings and bandages; we smell the nauseating gangrene and, at London’s stations, the gas clinging to the uniforms of the men arriving home.

There is a lot of misinformation thrown around today, especially Online. Headlines tell us to do this, not that - all in the name of living longer, better, thinner, younger. In Hype, Dr. Nina Shapiro distinguishes between the falsehoods and the evidence-backed truth. In her work at Harvard and UCLA, with more than 20 years of experience in both clinical and academic medicine, she helps patients make important health decisions everyday. She’s bringing those lessons to life here with a blend of science and personal stories to discuss her new definition of “a healthy life”.

For readers and listeners of Atul Gawande, Siddhartha Mukherjee, and Henry Marsh, a riveting, gorgeously written biography of one of history's most fascinating and confounding diseases - Alzheimer's - from its discovery more than 100 years ago to today's race toward a cure.

Long-time physician Sherwin B. Nuland presents a provocative and stimulating collection of stories illustrating the vagaries of medical practice over the years.

In 1918, a world war raged, and a lethal strain of influenza circled the globe. In the midst of all this death, a bizarre disease appeared in Europe. Eventually known as encephalitis lethargica, or sleeping sickness, it spread worldwide, leaving millions dead or locked in institutions. Then, in 1927, it disappeared as suddenly as it had arrived. Asleep, set in 1920s and '30s New York, follows a group of neurologists through hospitals and asylums as they try to solve this epidemic and treat its victims - who learned the worst fate was not dying of it, but surviving it.