Health Care History

This audiobook explores big questions like these, explaining the breakthroughs and discoveries that have shaped our modern-day understanding of medicine and helped us protect and promote our health. Written in plain English, The Medicine Book cuts through the jargon and is packed with pithy explanations of the most important milestones in medical history to untangle knotty concepts.

The first of our organs to form and the last to die, the heart is both a simple pump and the symbol of what makes us human; as long as it continues to beat, there is hope. In The Story of a Heart, Dr. Rachel Clarke interweaves the history of medical innovations behind transplant surgery with the story of two children—one of whom desperately needs a new heart.

In the early 1960s, Dr. Frances Oldham Kelsey of the U.S. Food and Drug Administration became one of the most celebrated women in America when she prevented a deadly sedative from entering the U.S. market. A Canadian-born pharmacologist and physician, Kelsey saved countless Americans from the devastating side effects of thalidomide, routinely given to pregnant women to prevent morning sickness. As the FDA medical officer charged with reviewing Merrell Pharmaceutical’s application for approval, Kelsey was unconvinced that there was sufficient evidence of the drug’s efficacy and safety.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

The year is 1925. It is sixty degrees below zero. The wind sweeps tons of snow over the deep-frozen Alaskan landscape. The nearest railhead is seven hundred miles away. Airplanes cannot fly. The way to Nome is blocked by a treacherous frozen sound, an icebound port, and mountains to the west. But there is a diphtheria epidemic in Nome. The children need serum from the outside world if they are to survive. Their only hope is a few chosen Eskimo drivers and their teams of dogs.

It began with a smoke break. James Monsees and Adam Bowen were two ambitious graduate students at Stanford, and in between puffs after class they dreamed of a way to quit smoking. Their solution became the Juul, a sleek, modern device that could vaporize nicotine into a conveniently potent dosage. Time magazine reporter Jamie Ducharme follows Monsees and Bowen as they create Juul and, in the process, go from public health visionaries and Silicon Valley wunderkinds to two of the most controversial businessmen in the country.

Government, industry, and the medical profession, however, have a mixed record when it comes to framing policies and generating knowledge to address drug use and misuse. In Strange Trips, Lucas Richert investigates the myths, meanings, and boundaries of recreational drugs, palliative care drugs, and pharmaceuticals as well as struggles over product innovation, consumer protection, and freedom of choice in the medical marketplace.

Sigmund Freud revolutionized the way in which we think about ourselves. From its beginnings as a theory of neurosis Freud developed psychoanalysis into a general psychology, which became widely accepted as the predominant mode of discussing personality and interpersonal relationships. Anthony Storr goes one step further and investigates the status of Freud's legacy today and the disputes that surround it.

Most stories of medical progress come with ready-made heroes. John Snow traced the origins of London's 1854 cholera outbreak to a water pump, leading to the birth of epidemiology. Florence Nightingale's contributions to the care of soldiers in the Crimean War transformed hospitals from crucibles of infection to sanctuaries of recuperation. Yet histories of individual innovators ignore many key sources of medical knowledge.

Antebellum New Orleans sat at the heart of America's slave and cotton kingdoms. It was also where yellow fever epidemics killed as many as 150,000 people during the nineteenth century. With little understanding of mosquito-borne viruses, a person's only protection against the scourge was to "get acclimated" by surviving the disease. Repeated epidemics bolstered New Orleans's strict racial hierarchy by introducing another hierarchy, what Kathryn Olivarius terms "immunocapital." Whereas immunity conferred privilege on whites, it relegated enslaved people to the most grueling labor.

For most of human history, mental illness has been largely untreatable. Sufferers lived their lives - if they survived - in and out of asylums, accumulating life's wreckage around them. In 1948, all that changed when an Australian doctor and recently returned prisoner of war, working alone in a disused kitchen, set about an experimental treatment for one of the scourges of mankind - manic depression, or bipolar disorder. That doctor was John Cade and in that small kitchen he stirred up a miracle.

Seamus O'Mahony writes about the illusion of progress, the notion that more and more diseases can be "conquered" ad infinitum. He punctures the idiocy of consumerism, the idea that healthcare can be endlessly adapted to the wishes of individuals. He excoriates the claims of Big Science, the spending of vast sums on research follies like the Human Genome Project. And he highlights one of the most dangerous errors of industrialized medicine: an over-reliance on metrics, and a neglect of things that can't easily be measured, like compassion.

A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.

For 200 years, a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. What these strange conditions share is their cause: prions.

For centuries, medicine has made reckless use of one of earth's most toxic substances: mercury - and the consequences, often invisible or ignored, continue to be tragic. Today, global emissions of mercury as well as other toxicants, make us all more vulnerable to its effects. From the worst cases of syphilis to Sigmund Freud's first cases of hysteria, from baffling new disorders in 19th century Britain to the modern scourge of autism, The Age of Autism traces the long overlooked history of mercury poisoning.

Filled with firsthand insights and stories from the frontlines of healthcare, as well as innovative solutions, Care After Covid shows all stakeholders in the healthcare ecosystem exactly what needs to change and, more importantly, how to do it.

Weaving together family history, genetic discovery, and scenes from her life, Ami McKay tells the compelling, true-science story of her own family's unsettling legacy of hereditary cancer while exploring the challenges that come from carrying the mutation that not only killed many people you loved, but might also kill you.

In this fascinating new exploration of mental illness, Professor Brendan Kelly examines ‘madness’ in history and how we have responded to it over the centuries. We travel from the psychiatric institutions of modern India to scientific studies of the brain in Victorian England. We discover the beginnings of formal asylum care and witness the experimental therapies of the cavernous psychiatric hospitals of the 19th and early 20th centuries in Ireland, England, Belgium, Italy, Germany and the United States.

A wide-ranging and provocative look - teeming with little-known facts and engaging stories - at a subject of the direst interest. Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled audiobook, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature....