Health Care History

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

An epic story told by a unique voice in Ameri­can medicine, One Doctor describes life-changing experiences in the career of a distinguished physi­cian. In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today.

Author Cory Franklin, MD, who headed the hospital's intensive care unit from the 1970s through the 1990s, shares his most unique and bizarre experiences, including the deadly Chicago heatwave of 1995, treating the first AIDS patients in the country before the disease was diagnosed, the nurse with rare Munchausen syndrome, the only surviving ricin victim, and the professor with Alzheimer's hiding the effects of the wrong medication.

The first major bioterror event in the United States - the anthrax attacks in October 2001 - was a clarion call for scientists who work with "hot" agents to find ways of protecting civilian populations against biological weapons. In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a number-one New York Times best seller, Richard Preston takes us into the heart of USAMRIID, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland.

The story of poison is the story of power. For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns, and antidotes tested on condemned prisoners. Servants licked the royal family's spoons, tried on their underpants, and tested their chamber pots. Ironically, royals terrified of poison were unknowingly poisoning themselves daily with their cosmetics, medications, and filthy living conditions.

The most fatal virus known to science, rabies kills nearly 100 percent of its victims once the infection takes root in the brain. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh, fascinating, and often wildly entertaining look at one of mankind’s oldest and most fearsome foes.

An acclaimed medical expert and patient advocate offers an eye-opening look at many common and widely used medical interventions that have been shown to be far more harmful than helpful. Yet, surprisingly, despite clear evidence to the contrary, most doctors continue to recommend them.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster. And yet, in our popular conception it exists largely as a footnote to World War I. Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered, and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.

A Healthy Society offers a new approach to politics–and a new approach to building a healthier world. Dr. Meili argues that health delivery too often focuses on treatment of immediate causes and ignores fundamental conditions that lead to poor health such as income, education, employment, housing, and environment.

The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic medication. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

A History of the World in Six Plagues shows that throughout history, outbreaks of disease have been exacerbated by and gone on to further expand the racial, economic, and sociopolitical divides we allow to fester in times of good health. Princeton-trained historian Edna Bonhomme’s examination of humanity’s disastrous treatment of pandemic disease takes us across place and time from Port-au-Prince to Tanzania, and from plantation-era America to our modern COVID-19-scarred world to unravel shocking truths about the patterns of discrimination in the face of disease.

A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.

Measles, once seemingly defeated, is resurgent around the globe. Why, at a time when biomedical science is so advanced, do parents turn away from vaccination, endangering their own children and the health of the wider population? Using a combination of patient narrative, historical analysis, and scientific research, Dr. Adam Ratner, pediatrician and infectious disease specialist, argues that the reawakening of measles and the subsequent coronavirus pandemic are bellwethers of forgotten knowledge—indicators of decaying trust in science and an underfunded public health infrastructure.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

In early 2020, the world was on edge. An ominous virus was spreading on different continents, and no one knew what the coming weeks would bring. Far from the hot spots, the cruise ship Zaandam, owned by Holland America, was preparing to sail from Buenos Aires, Argentina, loaded with 1,200 passengers—Americans, Europeans and South Americans, plus 600 crew. Within days, people aboard begin to fall sick. With only two doctors aboard and few medical supplies to test for or treat COVID-19, and with dwindling food and water, the ship wanders the oceans on an unthinkable journey.

In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert, where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it?