History Medicine Science

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease

To paraphrase the great sci-fi writer Stephen King: Kill your darlings, kill your darlings, even when it breaks your heart, kill your darlings. Translation: stay on point and mercilessly avoid side stories and anecdotes. With much respect for Mr. King, The History of Man Series is precisely that, a great deal about all those little darlings, a style of writing termed “jumping off.”

Interweaving history, original reportage, and personal narrative, Pandemic explores the origin of epidemics, drawing parallels between the story of cholera - one of history's most disruptive and deadly pathogens - and the new pathogens that stalk humankind today, from Ebola and avian influenza to drug-resistant superbugs.

An estimated 10 percent of Americans are implanted with medical devices - like pacemakers, artificial hips, cardiac stents, etc. The overwhelming majority of high-risk implanted devices have never undergone a single clinical trial. The FDA lets device manufacturers decide whether to report serious complications or deaths that may have been caused by their products. Here, award-winning journalist Jeanne Lenzer brings these horrifying statistics to life through the story of one working-class man who, after his "cure" nearly kills him, ends up in a battle for justice.

Get to know the ickiest illnesses that have infected humans and affected civilizations through the ages. Each chapter explores the story of a disease, including the scary symptoms, kooky cures, and brilliant breakthroughs that it spawned. Medical historian and bestselling author Lindsey Fitzharris lays out the facts with her trademark wit. Diseases covered in this audiobook include bubonic plague, smallpox, rabies, tuberculosis, cholera, and scurvy.

Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.

Every medical decision - whether to have chemotherapy, an X-ray, or surgery - is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from the first blood transfusions 400 years ago to the hunt for a COVID-19 vaccine, risk has been essential to the discovery of new treatments. More importantly, understanding the risks is crucial to whether, as a society or as individuals, we accept them.

In this unique history, you will discover how ill health has been with us for as long as humans have existed, as has the drive to treat and understand it. Over the course of centuries, the ways in which doctors have engaged with sickness has changed drastically, and so too have the tools at their disposal.

Blood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquitousness, the few tablespoons of blood discharged by 800 million women are still regarded as taboo: menstruation is perhaps the single most demonized biological event.

Sigmund Freud revolutionized the way in which we think about ourselves. From its beginnings as a theory of neurosis Freud developed psychoanalysis into a general psychology, which became widely accepted as the predominant mode of discussing personality and interpersonal relationships. Anthony Storr goes one step further and investigates the status of Freud's legacy today and the disputes that surround it.

Autrefois, les "potions" à base de plantes étaient confectionnées par des sorcières que l'on condamnait au bûcher par ignorance ou par jalousie. Aujourd'hui, l'industrie pharmaceutique utilise dans un grand nombre de cas les mêmes principes actifs. À la lumière des connaissances actuelles, le docteur Labescat nous fait revivre la formule de ces anciens philtres. Les lectrices auront plaisir à découvrir que l'angélique, au nom prédestiné, prolonge la beauté et que la consoude constitue un excellent raffermissant capable de donner l'illusion de la virginité.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

In 2009, an influential panel of medical experts ignited a controversy when they recommended that most women should not begin routine mammograms to screen for breast cancer until the age of 50, reversing guidelines they had issued just seven years before when they recommended 40 as the optimal age to start getting mammograms. Many women’s groups, health care advocates, and individual women saw the guidelines as privileging financial considerations over women’s health and a setback to decades-long efforts to reduce the mortality rate of breast cancer.

In the early 1960s, Dr. Frances Oldham Kelsey of the U.S. Food and Drug Administration became one of the most celebrated women in America when she prevented a deadly sedative from entering the U.S. market. A Canadian-born pharmacologist and physician, Kelsey saved countless Americans from the devastating side effects of thalidomide, routinely given to pregnant women to prevent morning sickness. As the FDA medical officer charged with reviewing Merrell Pharmaceutical’s application for approval, Kelsey was unconvinced that there was sufficient evidence of the drug’s efficacy and safety.

Ignác Semmelweis is remembered for the now-commonplace notion that doctors must wash their hands before examining patients. In mid-19th century Vienna, however, this was a subversive idea. With deaths from childbed fever exploding, Semmelweis discovered that doctors themselves were spreading the disease. While his simple reforms worked immediately - childbed fever in Vienna all but disappeared - they brought down upon Semmelweis the wrath of the establishment, and led to his tragic end.

Today it is known as Roosevelt Island. In 1828, when New York City purchased this narrow, two-mile-long island in the East River, it was called Blackwell's Island. There, over the next hundred years, the city would build a lunatic asylum, prison, hospital, workhouse, and almshouse. Stacy Horn has crafted a compelling and chilling narrative told through the stories of the poor souls sent to Blackwell's, as well as the period's city officials, reformers, and journalists (including the famous Nellie Bly). Damnation Island re-creates what daily life was like on the island....

For the truly well-rounded "intellectual," nothing fascinates so much as the subversive, the contrarian, the suppressed, and the bizarre. Richard Zacks has unloosed his admittedly strange mind and astonishing research abilities upon the entire spectrum of human knowledge, ferreting out endlessly fascinating facts, and stories guaranteed to make you laugh, gasp in wonder, and occasionally shudder at the depths of human depravity. The result of his labors is this quasi-encyclopedia that provides alternative takes on art, business, crime, science, medicine, sex (lots of that), and many other facets of human experience.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.