History Medicine Science

On November 23, 1849, in the heart of Boston, one of the city's richest men vanished. Dr. George Parkman, a Brahmin who owned much of Boston's West End, was last seen that afternoon visiting his alma mater, Harvard Medical School. Police scoured city tenements and the harbor - some leads put Parkman at sea or in Manhattan - but a Harvard janitor held a much darker suspicion: that their ruthless benefactor had never even left the Medical School building. His shocking discovery engulfed America in one of its most infamous trials.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.

John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the 20th century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today.

In Out Cold, science writer Phil Jaekl chronicles the underappreciated story of human innovation with cold, from Ancient Egypt, where it was used to treat skin irritations, to 18th-century London, where scientists used it in their first explorations of suspended animation. Throughout history, physicians have used cold to innovate life extension, enable distant space missions, and explore consciousness.

We all know the history of science that we learned from grade school textbooks: how Galileo used his telescope to show that the earth was not the center of the universe; how Newton divined gravity from the falling apple; how Einstein unlocked the mysteries of time and space with a simple equation. This history is made up of long periods of ignorance and confusion, punctuated once an age by a brilliant thinker who puts it all together. These few tower over the ordinary masses, and in the traditional account, it is to them that we owe science in its entirety. This belief is wrong.

Feeling feverish, tired, or achy? Listening to Gina Kolata's engrossing account of the 1918 Influenza epidemic is sure to give you the chills. A gripping work of science writing, Flu addresses the prospects for a great epidemic recurring, and considers what can be done to prevent it.

In 1920, at the end of the last major pandemic, global life expectancy was just over 40 years. Today, in many parts of the world, human beings can expect to live more than 80 years. As a species, we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity.

An estimated 10 percent of Americans are implanted with medical devices - like pacemakers, artificial hips, cardiac stents, etc. The overwhelming majority of high-risk implanted devices have never undergone a single clinical trial. The FDA lets device manufacturers decide whether to report serious complications or deaths that may have been caused by their products. Here, award-winning journalist Jeanne Lenzer brings these horrifying statistics to life through the story of one working-class man who, after his "cure" nearly kills him, ends up in a battle for justice.

In this unique history, you will discover how ill health has been with us for as long as humans have existed, as has the drive to treat and understand it. Over the course of centuries, the ways in which doctors have engaged with sickness has changed drastically, and so too have the tools at their disposal.

In State of the Heart, the journey to rid the world of heart disease is shown to be reflective of the journey of medical science at large. We are learning not only that women have as much heart disease as men, but that the type of heart disease women experience is diametrically different from that in men. We are learning that heart disease and cancer may have more in common than we could have imagined. And we are learning how human evolution itself may have led to the epidemic of heart disease

Is stress a deadly disease on the rise in modern society? Can mind-body practices from the East help us become well? When it comes to healing, we believe we must look beyond doctors and drugs; we must look within ourselves. Faith, relationships, and attitude matter. But why do we believe such things? From psychoanalysis to the placebo effect to meditation, this vibrant cultural history describes mind-body healing as rooted in a patchwork of stories, allowing us to make new sense of our suffering and to rationalize new treatments and lifestyles.

On June 25, 1973, a seven-year-old girl went missing from the Montana campground where her family was vacationing. Somebody had slit open the back of their tent and snatched her from under their noses. None of them saw or heard anything. Susie Jaeger had vanished into thin air, plucked by a shadow. As days stretched into weeks, and weeks into months, Special Agent Pete Dunbar attended a workshop at FBI Headquarters in Quantico, Virgina, led by two agents who had hatched a radical new idea: What if criminals left a psychological trail that would lead us to them?

To paraphrase the great sci-fi writer Stephen King: Kill your darlings, kill your darlings, even when it breaks your heart, kill your darlings. Translation: stay on point and mercilessly avoid side stories and anecdotes. With much respect for Mr. King, The History of Man Series is precisely that, a great deal about all those little darlings, a style of writing termed “jumping off.”

A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

In 2009, an influential panel of medical experts ignited a controversy when they recommended that most women should not begin routine mammograms to screen for breast cancer until the age of 50, reversing guidelines they had issued just seven years before when they recommended 40 as the optimal age to start getting mammograms. Many women’s groups, health care advocates, and individual women saw the guidelines as privileging financial considerations over women’s health and a setback to decades-long efforts to reduce the mortality rate of breast cancer.

Autrefois, les "potions" à base de plantes étaient confectionnées par des sorcières que l'on condamnait au bûcher par ignorance ou par jalousie. Aujourd'hui, l'industrie pharmaceutique utilise dans un grand nombre de cas les mêmes principes actifs. À la lumière des connaissances actuelles, le docteur Labescat nous fait revivre la formule de ces anciens philtres. Les lectrices auront plaisir à découvrir que l'angélique, au nom prédestiné, prolonge la beauté et que la consoude constitue un excellent raffermissant capable de donner l'illusion de la virginité.

If you don’t like going to the doctor, spare a thought for your ancestors. Got a headache? We can drill into your skull! Need to buy medicine? Can we recommend a dose of ground-up Egyptian mummy? Want to fight off diseases? Try smelling a stinky cesspit. It’s well-known that to make advances in science you have to make a few mistakes along the way. In this hilarious history book kids will be whisked around the world—from ancient Rome to imperial China—to meet the medical innovators who pushed the boundaries of what was possible, with sometimes disastrous effects.

A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective COVID-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer overcame a series of crises that were compounded by social and political unrest.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.