History Medicine Science

Decades of data cannot be ignored: African-American adults are far more likely to develop Type 2 diabetes than white adults. In a rousing indictment of the idea that notions of biological race should drive scientific inquiry, Sweetness in the Blood provides an ethnographic picture of biotechnology's framings of Type 2 diabetes risk and race and, importantly, offers a critical examination of the assumptions behind the recruitment of African American and African-descent populations for Type 2 diabetes research.

One hundred years after a milestone medical discovery, Insulin: The Crooked Timber tells the story of how insulin was transformed from what one clinician called "thick brown muck" into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Taking the listener on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, the book reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes.

The birth of psychiatry in the early nineteenth-century fundamentally changed how madness was categorized and understood. A century on, their conceptions of mental illness continue to influence our views today. Beliefs and behavior were divided up into the pathological and the healthy. The influence of religion and the supernatural became significant measures of insanity in individuals, countries, and cultures. Troubled by Faith explores these ideas about the supernatural across society through the prism of medical history.

Where did Spanish flu come from, and what can the possible sites of origin tell us today? This book looks at how Spanish flu changed the focus of scientific thought from eugenics to the creation of public health, and how it unfolded across each continent.

Pain is the number one reason people schedule medical appointments. Yet many people do not receive adequate relief, especially for chronic pain. Pain: The Culture and Science of Pain describes the multiple factors that contribute to the ongoing problem of unrelieved pain. There are both cultural and scientific reasons. The book discusses how various cultures and religions throughout history have downplayed the importance of relieving pain. Such biases persist today.

When Dr. David Hosack tilled the country's first botanical garden in the Manhattan soil more than 200 years ago, he didn't just dramatically alter the New York landscape; he left a monumental legacy of advocacy for public health and wide-ranging support for the sciences. In melodic prose, historian Victoria Johnson eloquently chronicles Hosack's tireless career to reveal the breadth of his impact. The result is a lush portrait of the man who gave voice to a new, deeply American understanding of the powers and perils of nature.

As a health-care journalist, Kate Pickert knew the emotional highs and lows of medical treatment well - but always from a distance, through the stories of her subjects. That is, until she was unexpectedly diagnosed with an aggressive type of breast cancer at the age of 35. As she underwent more than a year of treatment, Pickert realized that the popular understanding of breast care in America bears little resemblance to the experiences of today's patients and the rapidly changing science designed to save their lives.

The kidney is an extraordinary organ—in many ways the regulator, the metronome, the keeper of the human body’s delicate equilibrium. On a given day, minute by minute, it purifies the body of toxins it encounters from diet, climate, activity, and injury. It allows us to be and to move in the world. And yet most of us know so very little about these extraordinary vessels nestled in our bodies—and indeed millions of us only really learn about them when they stop working. Nearly a million Americans every year have end stage kidney disease, about 37 million have some form of chronic kidney disease.

Mysterious and misunderstood, distorted by biblical imagery of disfigurement and uncleanness, Hansen's disease or leprosy has all but disappeared from America's consciousness. In Carville, Louisiana, the closed doors of the nation's last center for the treatment of leprosy open to reveal stories of sadness, separation, and even strength in the face of what was once a life-wrenching diagnosis. Drawn from interviews with living patients and extensive research in the leprosarium's archives, Carville: Remembering Leprosy in America tells the stories of former patients.

Long before the U.S. government began conducting secret radiation and germ-warfare experiments, and long before the Tuskegee syphilis experiments, medical professionals had introduced—and hotly debated the ethics of—the use of human subjects in medical experiments. In Subjected to Science, Susan Lederer provides the first full-length history of biomedical research with human subjects in the earlier period, from 1890 to 1940.

Johns Hopkins University, one of the preeminent medical schools in the nation today, has played a unique role in the history of medicine. When it first opened its doors in 1893, medicine was a rough-and-ready trade. It would soon evolve into a rigorous science. In recent years, medical science has mapped the human genome, deployed robotic tools to perform delicate surgeries, and developed effective vaccines against a host of deadly pathogens. But this transformation could not have happened without the game-changing vision, talent, and dedication of a small cadre of individuals.

Arising from collaboration between a doctor and a historian, Disease and History offers the general listener a wide-ranging and accessible account of the ways in which disease has left its dramatic mark on the past. It discusses the impact made by bubonic plague and other infections upon the ancient and medieval worlds; the likely role of syphilis in the careers of Henry VIII and Ivan the Terrible; the significance of smallpox for the conquest of Mexico; and the contribution of typhus to Napoleon's downfall and of hemophilia to the collapse of Tsarist rule in Russia.

Government, industry, and the medical profession, however, have a mixed record when it comes to framing policies and generating knowledge to address drug use and misuse. In Strange Trips, Lucas Richert investigates the myths, meanings, and boundaries of recreational drugs, palliative care drugs, and pharmaceuticals as well as struggles over product innovation, consumer protection, and freedom of choice in the medical marketplace.

The Tragedy of American Science explores how the US economy’s addiction to military spending distorts and deforms science by making it overwhelmingly subservient to military interests. The primary motive driving American science and technology has become the search for new and more efficient ways to kill people. This transforms science from the classic ideal of a creative force for the advancement of humankind into its destructive and antihuman opposite.

Even the greatest minds in medicine have been terribly, terribly wrong. Boneheads and Brainiacs profiles the winners of the Nobel Prize in Medicine from 1901 to 1950 - a surprisingly diverse group of racists, cranks, and opportunists, as well as heroes, geniuses, and selfless benefactors of humanity. Forget all the ivory tower stereotypes of white-coated doctors finding miracle cures. Boneheads and Brainiacs reveals the messy human reality behind medical progress, in a highly entertaining audiobook for the ordinary listener.

As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955 the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections.

In this landmark medical narrative, Pulitzer Prize-winning journalists Mark Johnson and Kathleen Gallagher chronicle the story of Nic Volker, the Wisconsin boy at the center of a daring breakthrough in medicine - a complete gene sequencing to discover the cure for an otherwise undiagnosable illness.

On November 23, 1849, in the heart of Boston, one of the city's richest men vanished. Dr. George Parkman, a Brahmin who owned much of Boston's West End, was last seen that afternoon visiting his alma mater, Harvard Medical School. Police scoured city tenements and the harbor - some leads put Parkman at sea or in Manhattan - but a Harvard janitor held a much darker suspicion: that their ruthless benefactor had never even left the Medical School building. His shocking discovery engulfed America in one of its most infamous trials.

In 1900, the U.S. sent three doctors to Cuba to discover how yellow fever was spread. There, they launched one of history's most controversial human studies. Compelling and terrifying, The American Plague depicts the story of yellow fever and its reign in this country - and in Africa, where even today it strikes thousands every year. With "arresting tales of heroism," it is a story as much about the nature of human beings as it is about the nature of disease.

In Good Blood, best-selling writer Julian Guthrie tells the gripping tale of the race to cure a horrible affliction known as Rh disease that stalked families and caused a mother’s immune system to attack her own unborn child. The story is anchored by two very different men on two continents: Dr. John Gorman in New York, who would land on a brilliant yet contrarian idea, and the unassuming Australian whose almost magical blood - and his unyielding devotion to donating it - would save millions of lives.