History Medicine Science

Detrás de cada fármaco se esconde una historia. Puede ser la de un investigador excéntrico que resultó ser un genio, un momento decisivo en la historia geopolítica, un nuevo avance tecnológico o un inesperado pero afortunado efecto secundario descubierto en un ensayo clínico. A través de datos curiosos, anécdotas poco conocidas y personajes un tanto extravagantes, Thomas Hager propone un recorrido por las diez drogas más significativas de la historia a la vez que muestra la evolución de nuestra cultura y práctica de la medicina.

When a waiting world learned on April 12, 1955, that Jonas Salk had successfully created a vaccine to prevent poliomyelitis, he became a hero overnight. Born in a New York tenement, humble in manner, Salk had all the makings of a 20th-century icon - a knight in a white coat. In the wake of his achievement, he received a staggering number of awards and honors; for years his name ranked with Gandhi and Churchill on lists of the most revered people.

It’s hard today to remember how recently cancer was a silent killer, a dreaded disease about which people rarely spoke in public. In hospitals and doctors’ offices, conversations about malignancy were hushed and hope was limited. In this deeply researched book, Elaine Schattner reveals a sea change—from before 1900 to the present day—in how ordinary people talk about cancer. From Whispers to Shouts examines public perception of cancer through stories in newspapers and magazines, social media, and popular culture.

When British-born Elizabeth Blackwell earned her medical degree in America in 1849, there was an international outcry. Few at the time would have disagreed with the actress Fanny Kemble's remark - "What, trust a woman doctor - never!"

The birth of psychiatry in the early nineteenth-century fundamentally changed how madness was categorized and understood. A century on, their conceptions of mental illness continue to influence our views today. Beliefs and behavior were divided up into the pathological and the healthy. The influence of religion and the supernatural became significant measures of insanity in individuals, countries, and cultures. Troubled by Faith explores these ideas about the supernatural across society through the prism of medical history.

Vitamin C begins with scurvy, which afflicted Europe for four hundred years and killed millions. The reasons that a disease whose cure was known from the outset persisted over that time are at once baffling and familiar, and these trials eventually lead to invention of the science of epidemiology. Author Stephen M. Sagar MD then chronicles the discovery of vitamins at the beginning of the twentieth century, a story that encapsulates the rise of a scientific approach to nutrition but with surprising twists and turns.

In 2018, the first genetically modified babies were reportedly born in China, made possible by the invention of CRISPR technology in 2012. This controversial advancement overturned the preexisting moral consensus, which had held for over 50 years before: While gene editing an adult person was morally acceptable, modifying babies, and thus subsequent generations, crossed a significant moral line. John H. Evans here provides a meta-level guide to how these debates move forward and their significance to society.

Since 2010, it has been possible to determine a person's genetic makeup in a matter of days at an accessible cost for many millions of people. Along with this technological breakthrough there has emerged a movement to use this information to help prospective parents "eliminate preventable genetic disease". As the prospect of systematically excluding the appearance of unwanted mutations in our children comes within reach, David B. Goldstein examines the possible consequences from these types of choices.

A crucial component of anti-Black racism is the unconscionable disparity in health outcomes between Black and white Americans. Sickening examines this institutionalized inequality through dramatic, concrete events from the past two decades, revealing how unequal living conditions and inadequate medical care have become routine. From the spike in chronic disease after Hurricane Katrina to the lack of protection for Black residents during the Flint water crisis, author Anne Pollock takes listeners on a journey through the diversity of anti-Black racism operating in healthcare.

One hundred years after a milestone medical discovery, Insulin: The Crooked Timber tells the story of how insulin was transformed from what one clinician called "thick brown muck" into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Taking the listener on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, the book reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes.

¿Qué cenaremos hoy? Nos hemos confrontado a esta pregunta desde que el hombre descubrió el fuego, pero para Michael Pollan la manera en que la abordamos hoy en día podría llegar a determinar nuestra supervivencia en cuanto a especie. El hecho de que seamos omnívoros y podamos ingerir todo tipo de alimentos hace que nuestro acto de decidir qué queremos comer se vuelva un dilema, sobre todo ante la abundancia de productos que nos ofrece el desconcertante y traicionero mercado alimenticio.

Johns Hopkins University, one of the preeminent medical schools in the nation today, has played a unique role in the history of medicine. When it first opened its doors in 1893, medicine was a rough-and-ready trade. It would soon evolve into a rigorous science. In recent years, medical science has mapped the human genome, deployed robotic tools to perform delicate surgeries, and developed effective vaccines against a host of deadly pathogens. But this transformation could not have happened without the game-changing vision, talent, and dedication of a small cadre of individuals.

The kidney is an extraordinary organ—in many ways the regulator, the metronome, the keeper of the human body’s delicate equilibrium. On a given day, minute by minute, it purifies the body of toxins it encounters from diet, climate, activity, and injury. It allows us to be and to move in the world. And yet most of us know so very little about these extraordinary vessels nestled in our bodies—and indeed millions of us only really learn about them when they stop working. Nearly a million Americans every year have end stage kidney disease, about 37 million have some form of chronic kidney disease.

The Medical Committee for Human Rights was organized in the summer of 1964 by medical professionals, mostly white and Northern, to provide care and support for Civil Rights activists who were organizing black voters in Mississippi. They left their lives and lucrative private practices to march beside and tend the wounds of demonstrators from Freedom Summer, to the March on Selma, to the Chicago Democratic Convention of 1968.

A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

A History of the World in Six Plagues shows that throughout history, outbreaks of disease have been exacerbated by and gone on to further expand the racial, economic, and sociopolitical divides we allow to fester in times of good health. Princeton-trained historian Edna Bonhomme’s examination of humanity’s disastrous treatment of pandemic disease takes us across place and time from Port-au-Prince to Tanzania, and from plantation-era America to our modern COVID-19-scarred world to unravel shocking truths about the patterns of discrimination in the face of disease.

With its signature "DARE to keep kids off drugs" slogan and iconic t-shirts, DARE (Drug Abuse Resistance Education) was the most popular drug education program of the 1980s and 1990s. But behind the cultural phenomenon is the story of how DARE and other antidrug education programs brought the War on Drugs into schools and ensured that the velvet glove of antidrug education would be backed by the iron fist of rigorous policing and harsh sentencing.

Measles, once seemingly defeated, is resurgent around the globe. Why, at a time when biomedical science is so advanced, do parents turn away from vaccination, endangering their own children and the health of the wider population? Using a combination of patient narrative, historical analysis, and scientific research, Dr. Adam Ratner, pediatrician and infectious disease specialist, argues that the reawakening of measles and the subsequent coronavirus pandemic are bellwethers of forgotten knowledge—indicators of decaying trust in science and an underfunded public health infrastructure.

The End of the Beginning is a remarkable history of cancer treatment and the evolution of our understanding of its dynamic interplay with the immune system. Through Michael Kinch’s personal experience as a cancer researcher at Washington University and the head of the oncology program at a leading biotechnology company, we witness the incredible accumulation of breakthrough science and its rapid translation into life-saving technologies that have begun to dramatically increase the quality and quantity of life for cancer patients.

Weaving together information from official sources and personal interviews, Barbara Tomblin gives the first full-length account of the US Army Nurse Corps in the Second World War. She describes how over 60,000 army nurses, all volunteers, cared for sick and wounded American soldiers in every theater of the war, serving in the jungles of the Southwest Pacific, the frozen reaches of Alaska and Iceland, the mud of Italy and northern Europe, or the heat and dust of the Middle East.