History Medicine Science

Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases.

Doctors at War is a candid account of a trauma surgical team based, for a tour of duty, at a field hospital in Helmand, Afghanistan. Mark de Rond tells of the highs and lows of surgical life in hard-hitting detail, bringing to life a morally ambiguous world in which good people face impossible choices and in which routines designed to normalize experience have the unintended effect of highlighting war’s absurdity. With stories that are at once comical and tragic, de Rond captures the surreal experience of being a doctor at war.

On a Thursday in November of 2013, Guadalupe Morales waited anxiously with her sister-in-law and their four small children. Every Latino man who drove away from their shared apartment above a small auto repair shop that day had failed to return - arrested, one by one, by ICE agents and local police. As the two women discussed what to do next, a SWAT team clad in body armor and carrying assault rifles stormed the room. In Separated, William D. Lopez examines the lasting damage done by this daylong act of collaborative immigration enforcement in Washtenaw County, Michigan.

At first glance, the events in this book may seem equal parts science fiction and legal thriller. Unfortunately, this is a true story of blinding greed, cruel deceit, unfortunate circumstance, and powerful human tragedy. It has villains and heroes, but it does not yet have a good ending. It is the story of asbestos in America.

In 2006, the Wall Street pioneer and philanthropist Ray Chambers flicked through some holiday snapshots taken by a friend and remarked on the placid beauty of a group of sleeping Malawian children. "They're not sleeping," his friend told him. "They're in malarial comas. A few days later, they were all dead." This moment sparked Chambers' determination to coordinate an unprecedented, worldwide effort to eradicate a disease that has haunted humanity since before the advent of medicine.

In the 16th century, when explorers travelled deep into the jungles of South America in search of gold and spices, they brought back many colourful tales of their adventures. None of these tales was more astonishing, or caused more concern, than that of the mystical properties of the substance with which the natives anointed their darts and arrows.

Princeton's McCormick Professor of Jurisprudence Robert P. George and USC's Graduate Director of Philosophy Christopher Tollefsen are experts in the field of bioethics. In Embryo: A Defense of Human Life, these esteemed scholars combine the latest scientific breakthroughs with the soundest tenets of philosophy to shed new light on a vital yet controversial issue of our day.

Few diseases are more gruesome than typhus. Transmitted by body lice, it afflicts the dispossessed - refugees, soldiers, and ghettoized peoples - causing hallucinations, terrible headaches, boiling fever, and often death. The disease plagued the German army on the Eastern Front and left the Reich desperate for a vaccine. For this they turned to the brilliant and eccentric Polish zoologist Rudolf Weigl.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations.

With its signature "DARE to keep kids off drugs" slogan and iconic t-shirts, DARE (Drug Abuse Resistance Education) was the most popular drug education program of the 1980s and 1990s. But behind the cultural phenomenon is the story of how DARE and other antidrug education programs brought the War on Drugs into schools and ensured that the velvet glove of antidrug education would be backed by the iron fist of rigorous policing and harsh sentencing.

In Change Is Possible, public health legend William H. Foege and five coauthors chronicle the failures and successes of global health through the modern age, including the massive impacts of colonialism, religious groups, philanthropies, politics, NGOs, and more. Foege, who has served in local, national, and international public health contexts is uniquely qualified to reflect on the history of global health. He and his Rollins School of Public Health coauthors explain why colonialism has been the greatest disaster for global health, whereas military medicine may have been its greatest asset.

When British-born Elizabeth Blackwell earned her medical degree in America in 1849, there was an international outcry. Few at the time would have disagreed with the actress Fanny Kemble's remark - "What, trust a woman doctor - never!"

Alles begann mit einer Doktorarbeit und der Entdeckung des medizinischen Potenzials des Botenmoleküls messenger RNA. Am Ende stehen prominente Investoren wie Dietmar Hopp oder die Gates-Stiftung, Hunderte Millionen staatlicher Finanzierung, der Aufstieg zum Börsenstar und zum erfolgreichen Impfstoffentwickler. Dazwischen liegt ein steiniger Weg auf der Suche nach Unterstützung. Biotech-Unternehmer Wolfgang Klein hat die Anfangszeit als Finanzchef von CureVac selbst miterlebt. Er erzählt die einzigartige und anekdotenreiche Geschichte auf dem Weg zum Weltunternehmen.

Humankind has always wrestled with the existence of suffering. For two centuries, many American ministers, physicians, and scientists believed that an omnipotent and omniscient God created the world such that people might relieve suffering through ingenuity and learning. Others responded to the new worldview introduced by the scientific revolution as a threat to the divine order. In Imagining Progress, Kristin Johnson traces the history of Americans' evolving relationship with science and religion at "one of its most dramatic places"—the bedsides of dying children.

Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Michael Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent - and could easily be undone. Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.

Decades of data cannot be ignored: African-American adults are far more likely to develop Type 2 diabetes than white adults. In a rousing indictment of the idea that notions of biological race should drive scientific inquiry, Sweetness in the Blood provides an ethnographic picture of biotechnology's framings of Type 2 diabetes risk and race and, importantly, offers a critical examination of the assumptions behind the recruitment of African American and African-descent populations for Type 2 diabetes research.

One hundred years after a milestone medical discovery, Insulin: The Crooked Timber tells the story of how insulin was transformed from what one clinician called "thick brown muck" into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Taking the listener on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, the book reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes.

The birth of psychiatry in the early nineteenth-century fundamentally changed how madness was categorized and understood. A century on, their conceptions of mental illness continue to influence our views today. Beliefs and behavior were divided up into the pathological and the healthy. The influence of religion and the supernatural became significant measures of insanity in individuals, countries, and cultures. Troubled by Faith explores these ideas about the supernatural across society through the prism of medical history.