Human Genetics

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

Drawing on startling new evidence from the mapping of the genome, an explosive new account of the genetic basis of race and its role in the human story. Human evolution, the consensus view insists, ended in prehistory. Inconveniently, as Nicholas Wade argues in A Troublesome Inheritance, the consensus view cannot be right. And in fact, we know that populations have changed in the past few thousand years - to be lactose tolerant, for example, and to survive at high altitudes.

In The Invisible History of the Human Race, Christine Kenneally draws on cutting-edge research to reveal how both historical artifacts and DNA tell us where we come from and where we may be going. While some books explore our genetic inheritance and some popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy.

Homo sapiens emerged as a species about 200,000 years ago and soon—with fire, simple tools, and an egalitarian social system—we inhabited every continent. But now our infinitely elaborated tools and our highly non-egalitarian social system threaten sustainability. Many at the bottom lose the desire to live, committing suicide or succumbing to drugs, alcohol, and obesity. What is Health? explains from the bottom up—molecules to society—how we reached this point.

Some 73,000 years ago, the Mount Toba supervolcano in toda's Indonesia erupted, releasing the energy of a million tons of explosives. So much ash and debris was injected into the stratosphere that it partially blocked the sun's radiation and caused global temperatures to drop for a decade. In this book, Donald R. Prothero presents the controversial argument that the Toba catastrophe nearly wiped out the human race, leaving only about a thousand to ten thousand breeding pairs of humans worldwide.

Mit Milliarden auf meinem Konto und meiner eigenen Risikokapitalgesellschaft bin ich der lebende amerikanische Traum. Mein einziges Problem? Nach einem Autounfall leidet meine Mutter an Gedächtnisproblemen.

Here is the extraordinary story of the unfolding of life on Earth, told by Michael J. Benton, a world-renowned authority on biodiversity. Ranging over four billion years, Benton weaves together the latest findings on fossils, earth history, evolutionary biology, and many other fields to highlight the great leaps that enabled life to evolve from microbe to human - big breakthroughs that made whole new ways of life possible - including cell division and multicellularity, hard skeletons, the move to land, the origin of forests, the move to the air.

Blending history, science, and culture, a stunning and highly engaging evolutionary story exploring how walking on two legs allowed humans to become the planet’s dominant species.

An eye-opening look into why our bodies work - or don’t - the way they do. From blurry vision to crooked teeth, ACLs (anterior cruciate ligaments) that tear at alarming rates and spines that seem to spend a lifetime falling apart, it’s surprising that human beings have beaten the odds as a species. After all, we’re the only survivors on our branch of the tree of life. In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us from where we inherited our adaptable, achy, brilliant bodies in the process of evolution.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

Nicolelis undertakes the first attempt to explain the entirety of human history, culture, and civilization based on a series of recently uncovered key principles of brain function. This new cosmology is centered around three fundamental properties of the human brain: its insurmountable malleability to adapt and learn; its exquisite ability to allow multiple individuals to synchronize their minds around a task, goal, or belief; and its incomparable capacity for abstraction.

It feels like a fairy tale when Alberta ”Bert” Monte receives a letter addressed to “Countess Alberta Montebianco” at her Hudson Valley, New York, home that claims she’s inherited a noble title, money, and a castle in Italy. While Bert is more than a little skeptical, the mystery of her aristocratic family’s past, and the chance to escape her stressful life for a luxury holiday in Italy, is too good to pass up.

Akshaya is the hybrid daughter of a human mother and an alloy, a genetically engineered posthuman—and she’s the future of life on the planet Meru. But not if the determined Akshaya can help it. Before choosing where her future lies, she wants to circumnavigate the most historic orb in the universe—the birthplace of humanity: Earth.

“There is no good reason why human societies should not be described and explained with the same precision and success as the rest of nature.” Thus argues evolutionary psychologist Pascal Boyer in this uniquely innovative book. Integrating recent insights from evolutionary biology, genetics, psychology, economics, and other fields, Boyer offers precise models of why humans engage in social behaviors such as forming families, tribes, and nations, or creating gender roles.

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

Between what can be learned from evolutionary psychology and cognitive science a picture emerges. In Sex, Murder, and the Meaning of Life, social psychologist Douglas Kenrick fuses these two fields to create a coherent story of human nature. In his analysis, many ingrained, apparently irrational behaviors—one-night stands, prejudice, conspicuous consumption, even art and religious devotion—are quite explicable and (when desired) avoidable.

For five centuries, human life has been restricted to Earth, while posthuman descendants called alloys freely explore the galaxy. But when the Earthlike planet of Meru is discovered, two unlikely companions venture forth to test the habitability of this unoccupied new world and the future of human-alloy relations. For Jayanthi, the adopted human child of alloy parents, it’s an opportunity to rectify the ancient reputation of her species as avaricious and destructive, and to give humanity a new place in the universe.

Our species has amassed unprecedented knowledge of nature, which we have tried to use to seize control of life and bend the planet to our will. In A Natural History of the Future, biologist Rob Dunn argues that such efforts are futile. We may see ourselves as life’s overlords, but we are instead at its mercy. In the evolution of antibiotic resistance, the power of natural selection to create biodiversity, and even the surprising life of the London Underground, Dunn finds laws of life that no human activity can annul.

The Secret Body is a gripping drama of discovery and a landmark account of the dawning revolution in human health that reveals a hitherto invisible universe within each of us.

In its 4.5 billion–year history, life on Earth has been almost erased at least half a dozen times: shattered by asteroid impacts, entombed in ice, smothered by methane, and torn apart by unfathomably powerful megavolcanoes. And we know that another global disaster is eventually headed our way. Can we survive it? How?

As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.
It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just
during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.
This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.
Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.