Human Genetics

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

In its 4.5 billion–year history, life on Earth has been almost erased at least half a dozen times: shattered by asteroid impacts, entombed in ice, smothered by methane, and torn apart by unfathomably powerful megavolcanoes. And we know that another global disaster is eventually headed our way. Can we survive it? How?

As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.
It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just
during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.
This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.
Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

When did the human species turn against the planet that we depend on for survival? Human industry and consumption of resources have altered the climate, polluted the water and soil, destroyed ecosystems, and rendered many species extinct, vastly increasing the likelihood of an ecological catastrophe. How did humankind come to rule nature to such an extent? To regard the planet's resources and creatures as ours for the taking? To find ourselves on a seemingly relentless path toward ecocide?

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

In The Invisible History of the Human Race, Christine Kenneally draws on cutting-edge research to reveal how both historical artifacts and DNA tell us where we come from and where we may be going. While some books explore our genetic inheritance and some popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy.

Once, we humans could only observe evolution. Suddenly, we had conquered it. And yet, in Life as We Made It, evolutionary biologist Beth Shapiro argues that - despite how amazing our new technologies are - our ability to alter the course of evolution isn’t new. What is new is that where once we shaped evolution through brute force, we can now do it as artisans. That power comes not a moment too soon. If we are going to survive in the next few centuries, we must revise the book of life.

Bill McKibben, examines the dangers inherent in an array of technologies that threaten not just our survival, but our identity. Imagine a future where lab workers can reprogram human embryos to make our children "smarter" or "more sociable" or "happier." Enough examines such possibilities, and explains how we can avoid their worst consequences while still enjoying the fruits of our new scientific understandings.

Humans, it turns out, are intrinsically wired to seek short-term success at the expense of long-term prosperity. Kristian Rönn, an entrepreneur formerly affiliated with the University of Oxford’s Future of Humanity Institute, calls these deeply rooted impulses “Darwinian demons.” These forces, a by-product of natural selection, can lead us to act in shortsighted ways that harm others—and even imperil our survival as a species. If this evolutionary glitch is left unchecked, the consequences will grow in magnitude as the power of technology accelerates.

Nature, it has been said, invites us to eat by appetite and rewards by flavor. But what exactly are flavors? Why are some so pleasing while others are not? Delicious is a supremely entertaining foray into the heart of such questions. With generous helpings of warmth and wit, Rob Dunn and Monica Sanchez offer bold new perspectives on why food is enjoyable and how the pursuit of delicious flavors has guided the course of human history.

As biologist Jeremy Griffith explains in The Interview (which psychiatrist Professor Harry Prosen described as the most important interview of all time), while we humans lacked the explanation for our 2-million-year corrupted human condition we had no choice but to deny that our distant ape ancestors lived in a state of cooperative and loving innocence.

Humans are awesome. Our brains are gigantic, seven times larger than they should be for the size of our bodies. The human brain uses 25 percent of all the energy the body requires each day. And it became enormous in a very short amount of time in evolution, allowing us to leave our cousins, the great apes, behind. So the human brain is special, right? Wrong, according to Suzana Herculano-Houzel. Humans have developed cognitive abilities that outstrip those of all other animals but not because we are evolutionary outliers.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

It feels like a fairy tale when Alberta ”Bert” Monte receives a letter addressed to “Countess Alberta Montebianco” at her Hudson Valley, New York, home that claims she’s inherited a noble title, money, and a castle in Italy. While Bert is more than a little skeptical, the mystery of her aristocratic family’s past, and the chance to escape her stressful life for a luxury holiday in Italy, is too good to pass up.

How did humans come to be who we are? In his marvelous, eccentric, and widely lauded book Being a Beast, legal scholar, veterinary surgeon, and naturalist extraordinaire Charles Foster set out to understand the consciousness of animal species by living as a badger, otter, fox, deer, and swift. Now, he inhabits three crucial periods of human development to understand the consciousness of perhaps the strangest animal of all—the human being.

An eye-opening look into why our bodies work - or don’t - the way they do. From blurry vision to crooked teeth, ACLs (anterior cruciate ligaments) that tear at alarming rates and spines that seem to spend a lifetime falling apart, it’s surprising that human beings have beaten the odds as a species. After all, we’re the only survivors on our branch of the tree of life. In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us from where we inherited our adaptable, achy, brilliant bodies in the process of evolution.

In 1997, Yiannis Kouros ran 188 miles in 24 hours. In 1984, at age 42, Maria Moreira gave birth to her 10th set of twins. In 1973, Terry Tao learned to read when he was two years old. Tao started college at age nine, and at 24 was appointed a full-time professor at UCLA. What does it feel like to be exceptional? And what does it take to get there? Why can some people achieve greatness when others can’t, no matter how hard they try? Just how much potential does our species have? Evolutionary biologist Rowan Hooper has the answers.

Homo sapiens emerged as a species about 200,000 years ago and soon—with fire, simple tools, and an egalitarian social system—we inhabited every continent. But now our infinitely elaborated tools and our highly non-egalitarian social system threaten sustainability. Many at the bottom lose the desire to live, committing suicide or succumbing to drugs, alcohol, and obesity. What is Health? explains from the bottom up—molecules to society—how we reached this point.

In this paradigm-shattering book, biologist Mark W. Moffett draws on findings in psychology, sociology, and anthropology to explain the social adaptations that bind societies. He explores how the tension between identity and anonymity defines how societies develop, function, and fail. Surpassing Guns, Germs, and Steel and Sapiens, The Human Swarm reveals how mankind created sprawling civilizations of unrivaled complexity - and what it will take to sustain them.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

Our species has amassed unprecedented knowledge of nature, which we have tried to use to seize control of life and bend the planet to our will. In A Natural History of the Future, biologist Rob Dunn argues that such efforts are futile. We may see ourselves as life’s overlords, but we are instead at its mercy. In the evolution of antibiotic resistance, the power of natural selection to create biodiversity, and even the surprising life of the London Underground, Dunn finds laws of life that no human activity can annul.