Human Genetics

In its 4.5 billion–year history, life on Earth has been almost erased at least half a dozen times: shattered by asteroid impacts, entombed in ice, smothered by methane, and torn apart by unfathomably powerful megavolcanoes. And we know that another global disaster is eventually headed our way. Can we survive it? How?

As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.
It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just
during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.
This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.
Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

As biologist Jeremy Griffith explains in The Interview (which psychiatrist Professor Harry Prosen described as the most important interview of all time), while we humans lacked the explanation for our 2-million-year corrupted human condition we had no choice but to deny that our distant ape ancestors lived in a state of cooperative and loving innocence.

How did humans come to be who we are? In his marvelous, eccentric, and widely lauded book Being a Beast, legal scholar, veterinary surgeon, and naturalist extraordinaire Charles Foster set out to understand the consciousness of animal species by living as a badger, otter, fox, deer, and swift. Now, he inhabits three crucial periods of human development to understand the consciousness of perhaps the strangest animal of all—the human being.

In Unfit for Purpose, biologist and broadcaster Adam Hart explores the mismatch between our fundamental biology and the modern world we have created. In each chapter Adam reveals the many ways in which biological adaptations that evolved to help us survive and thrive now work against us. For example, in the modern world stress is a killer, but how did 'fight or flight' instincts turn from life-savers to life-takers? Obesity might be a disease now, but is it really just a troublesome side-effect of our complex evolutionary past?

Our species has amassed unprecedented knowledge of nature, which we have tried to use to seize control of life and bend the planet to our will. In A Natural History of the Future, biologist Rob Dunn argues that such efforts are futile. We may see ourselves as life’s overlords, but we are instead at its mercy. In the evolution of antibiotic resistance, the power of natural selection to create biodiversity, and even the surprising life of the London Underground, Dunn finds laws of life that no human activity can annul.

Bill McKibben, examines the dangers inherent in an array of technologies that threaten not just our survival, but our identity. Imagine a future where lab workers can reprogram human embryos to make our children "smarter" or "more sociable" or "happier." Enough examines such possibilities, and explains how we can avoid their worst consequences while still enjoying the fruits of our new scientific understandings.

In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos - as dramatic a development in genetics as the cloning of Dolly the sheep was in 1996. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention.

Humans, it turns out, are intrinsically wired to seek short-term success at the expense of long-term prosperity. Kristian Rönn, an entrepreneur formerly affiliated with the University of Oxford’s Future of Humanity Institute, calls these deeply rooted impulses “Darwinian demons.” These forces, a by-product of natural selection, can lead us to act in shortsighted ways that harm others—and even imperil our survival as a species. If this evolutionary glitch is left unchecked, the consequences will grow in magnitude as the power of technology accelerates.

منذ صدور هذا الكتاب لقي الكثير من الاستحسان حول العالم، وبخاصة من عامة الناس من غير المتخصصين في علم الأنثروبولوجيا، الذين لا يمكنهم قراءة الكتب الأكاديمية وبخاصة كتب التاريخ والأنثروبولوجيا المتخصصة جداً، فأسلوبه في الكتابة جاء سلساً وسهلاً وجعل الأفكار العلمية المعقدة قريبة للفهم، كما أنه دعم آراءه بمصادر علمية موثوقة من دون الجزم بصحتها تاركاً لمن يطّلع عليها إمكانية نقضها أو تطويرها حسب فكره الخاص ومنطقه وإدراكه للأمور.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

Here is the extraordinary story of the unfolding of life on Earth, told by Michael J. Benton, a world-renowned authority on biodiversity. Ranging over four billion years, Benton weaves together the latest findings on fossils, earth history, evolutionary biology, and many other fields to highlight the great leaps that enabled life to evolve from microbe to human - big breakthroughs that made whole new ways of life possible - including cell division and multicellularity, hard skeletons, the move to land, the origin of forests, the move to the air.

Humans are awesome. Our brains are gigantic, seven times larger than they should be for the size of our bodies. The human brain uses 25 percent of all the energy the body requires each day. And it became enormous in a very short amount of time in evolution, allowing us to leave our cousins, the great apes, behind. So the human brain is special, right? Wrong, according to Suzana Herculano-Houzel. Humans have developed cognitive abilities that outstrip those of all other animals but not because we are evolutionary outliers.

In The Invisible History of the Human Race, Christine Kenneally draws on cutting-edge research to reveal how both historical artifacts and DNA tell us where we come from and where we may be going. While some books explore our genetic inheritance and some popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy.

It feels like a fairy tale when Alberta ”Bert” Monte receives a letter addressed to “Countess Alberta Montebianco” at her Hudson Valley, New York, home that claims she’s inherited a noble title, money, and a castle in Italy. While Bert is more than a little skeptical, the mystery of her aristocratic family’s past, and the chance to escape her stressful life for a luxury holiday in Italy, is too good to pass up.

A natural history of the wilderness in our homes, from the microbes in our showers to the crickets in our basements Even when the floors are sparkling clean and the house seems silent, our domestic domain is wild beyond imagination. In Never Home Alone, biologist Rob Dunn introduces us to the nearly 200,000 species living with us in our own homes, from the Egyptian meal moths in our cupboards and camel crickets in our basements to the lactobacillus lounging on our kitchen counters. You are not alone.

An eye-opening look into why our bodies work - or don’t - the way they do. From blurry vision to crooked teeth, ACLs (anterior cruciate ligaments) that tear at alarming rates and spines that seem to spend a lifetime falling apart, it’s surprising that human beings have beaten the odds as a species. After all, we’re the only survivors on our branch of the tree of life. In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us from where we inherited our adaptable, achy, brilliant bodies in the process of evolution.

Nature, it has been said, invites us to eat by appetite and rewards by flavor. But what exactly are flavors? Why are some so pleasing while others are not? Delicious is a supremely entertaining foray into the heart of such questions. With generous helpings of warmth and wit, Rob Dunn and Monica Sanchez offer bold new perspectives on why food is enjoyable and how the pursuit of delicious flavors has guided the course of human history.

Homo sapiens emerged as a species about 200,000 years ago and soon—with fire, simple tools, and an egalitarian social system—we inhabited every continent. But now our infinitely elaborated tools and our highly non-egalitarian social system threaten sustainability. Many at the bottom lose the desire to live, committing suicide or succumbing to drugs, alcohol, and obesity. What is Health? explains from the bottom up—molecules to society—how we reached this point.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.