Medical Diseases

At just past 70, Alex Witchel’s smart, adoring, ultra-capable mother began to exhibit undeniable signs of dementia. Witchel reacted as she’d been raised: If something was broken, she would fix it. But as medical reality undid that hope, she retreated to the kitchen, trying to reclaim the mother who was disappearing in plain sight, by cooking the comforting foods that were her mother’s signature. Reproducing the perfect meat loaf was no panacea, but it helped a grieving daughter come to terms with her predicament, the growing phenomenon of "ambiguous loss" - loss of a beloved one who lives on.

Hayley Okines is like no other 13-year-old schoolgirl. In Old Before My Time, Hayley and her mum, Kerry, reflect on her unusual life. Share Hayley’s excitement as she travels the world meeting her pop heroes Kylie, Girls Aloud, and Justin Bieber and her sadness as she loses her best friend to the disease at the age of 11. Now as she passes the age of 13 - the average life expectancy for a child with progeria - Hayley talks frankly about her hopes for the future and her pioneering drug trials in America which could unlock the secrets of ageing for everyone....

Pro football Hall of Famer Jim Kelly and his wife, Jill, were catapulted from a seemingly fairy-tale life of celebrity into a world of private struggle and medical uncertainty. What the public didn’t know, however, was that behind the scenes lurked more than a family’s pain at the dire prognosis of their only son. Hunter’s illness exposed the troubled depths of a marriage that had long been shadowed by uncertainties of its own.

Called a "groundbreaking masterpiece" by Dr. Gregory O'Shanick, medical director emeritus of the Brain Injury Association of America, this is the gold edition of the unabridged audiobook of the critically acclaimed memoir The Day My Brain Exploded, which tells the story of Ashok Rajamani, a first-generation Indian American who had to relearn everything about life after a full-throttle brain hemorrhage at 25. With humor and insight, he describes the events of that day (his brain exploded just before his brother's wedding!) as well as the long, difficult recovery period. In the process he introduces listeners to his family - his principal support group as well as a constant source of frustration and amazement. Irreverent, coruscating, angry, at times shocking, but always revelatory, his memoir takes the listener into unfamiliar territory, much like the experience Alice had when she fell down the rabbit hole. That he lived to tell the story is miraculous; that he tells it with such aplomb is simply remarkable.

National Book Award winner Jonathan Kozol is best known for his 50 years of work among our nation's poorest and most vulnerable children. Now, in the most personal book of his career, he tells the story of his father's life and work as a nationally noted specialist in disorders of the brain and his astonishing ability, at the onset of Alzheimer's disease, to explain the causes of his sickness and then to narrate, step by step, his slow descent into dementia.

After a full-throttle brain bleed at the age of 25, Ashok Rajamani, a first-generationIndian American, had to relearn everything: how to eat, how to walk and speak, even things as basic as his sexual orientation. With humor and insight, he describes the events of that day - his brain exploded just before his brother's wedding - as well as the long, difficult recovery period. In the process, he introduces listeners to his family - his principal support group, as well as a constant source of frustration and amazement.

This taut yet lyrical memoir tells of the author’s experience with a baffling illness poised to take her sight, and gives a deeply felt meditation on vulnerability and on what it means to lose the faith you had and find something better. One day at the end of 2009, during a routine eye exam that Nora Gallagher nearly skipped, her doctor said, “Darn.” Her right optic nerve was inflamed, the cause unknown, a condition that if left untreated would cause her to lose her sight.

The word conquer has changed meaning for Bryan Anderson. As a U.S. army sergeant in Iraq, it meant taking down the enemy. After becoming Iraq’s fourth triple amputee from a roadside explosive, what he had to conquer got a bit more personal. On October 23, 2005, the moment Bryan looked down and realized he no longer had legs, he cracked a joke. It was a tragedy that could break many, but Bryan transformed it into something positive, something that propelled him forward.

Craig Huber was living the dream. Now a hard-working sales professional with an unswervingly supportive and caring wife by his side, after nearly two decades serving as a full-time minister in Central and South America, he knew how blessed his life had been. But when odd physical symptoms sent him to the doctor, his heart sank at the crippling words of his physician: late-stage liver disease.

What is it like to encounter cancer? How does it feel to face the unknown, to enter a world of hope, loss, and dread? From the diagnosis of his childhood friend’s mother to his poignant memories in the lab, David Scadden’s seen the unknown world of cancer from the lens of a young boy, a classmate, a researcher, a friend, a doctor, and a neighbor. Scadden chronicles his personal memories of cancer - his visits to his sick neighbor and his classmate who left school and never came back.

Fourteenth-century physician Alejandro Guzman, caught performing an autopsy in Spain, flees across Europe at the time of the Black Death to escape execution for his heretical deed. When he arrives in the Papal city of Avignon, he is conscripted against his will to serve as a Plague Doctor in the court of England's Edward III. Unfolding in a dramatic counterpoint is the story of American medical archaeologist Janie Crowe, in England at the turn of the 21st century to recover from the tragic loss of her family.

Straight out of today’s hospitals and labs–and tomorrow’s headlines–comes a frightening, scalpel-sharp thriller from medical insider Joshua Spanogle. In an astounding debut, Spanogle takes us on an all-too-real race against time…as a young doctor enters the dark side of scientific research, desperate to stop a terrifying epidemic before it is too late….

An internist and clinical instructor at Harvard Medical School fuses Eastern practices with cutting-edge Western medicine to help you connect body and mind to transform your health today and tomorrow.

It's Saturday, and everything is different. No, I didn't go to the market this morning, and I didn't have my usual coffee on Westerstraat. And no, I wasn't getting ready for a new semester at college. Next Monday, January 31, I have to admit myself at the hospital for my first chemotherapy session. For the next two months, I'm expected each week for a fresh shot of vincristine, etoposide, ifosfamide, and loads more exciting abracadabra.

Cancer can result from abnormal proliferation of any of the different kinds of cells in the body, so there are more than 100 distinct types of cancer, which can vary substantially in their behavior and response to treatment. Cancer occurs when cell division gets out of control. One of the fundamental features of cancer is tumor clonality, the development of tumors from single cells that begin to proliferate abnormally. Rare cancers are any tumors that involve a small percentage of the population in any age group.

Anticipating a career in medicine, Dr. William A. Haseltine was in his first weeks of graduate studies at Harvard when a legendary physician-scientist offered this advice: “You can do more for human health through science than you ever could as a doctor.” That advice hit him “like a thunderbolt” - and he took it. Since then, Dr. Haseltine has helped combat cancers, worked to contain the HIV/AIDS pandemic and unlocked the power of the human genome to develop dozens of new pharmaceutical cures.

At 49 years old, Carol Clupny was an active, driven woman with a career, a family, and a zest for adventure. A mere year later, she struggles with strange symptoms of internal tremors, frozen shoulders, and a serious intestinal infection. She doesn’t understand why she can’t paddle a kayak or throw the ball for her dogs. Then comes the diagnosis: early onset Parkinson’s Disease. Carol is not afraid to face the apathy and depression. Instead of being drug down into darkness, she finds strategies for lifting herself, and others around her, up into the light.

Dr. George Cotzias lived a large life. He stood over six feet tall; he drank Metaxa like milk; he smoked cigarettes as if eating candy. He bullied patients, sometimes looming over their wasted bodies. He had “a stare as strong as death”. His passion for women, his wife, and others was infamous. His voice boomed through the halls of the hospital where he was chief of physiology research.

Five months pregnant, Amanda Adams and her husband were given two abysmal choices regarding her pregnancy: force her baby to fight for his life through countless invasive and dangerous surgeries, or perform a late term abortion. Despite the fact that Liam was missing half his heart, Amanda chose life. Amanda's emotional plate was full as she found herself redefining the usual expectations a mother has for her child. Instead of wondering where he'd go to college, she wondered if he would survive his first birthday. The eventual acceptance of Amanda's grief helped her accept her new role as a powerful advocate.

Ross Donaldson is one the few who have ventured into dark territory of a country ravaged by war to study one of the world's most deadly diseases. As an untried medical student studying the intersection of global health and communicable disease, Donaldson soon found himself in dangerous Sierra Leone, on the border of war-struck Liberia, where he struggled to control the spread of Lassa Fever. The words, "you know Lassa can kill you, don't you?" haunted him each day. He'ss forced to make life-and-death decisions alone as a never-ending onslaught of contagious patients flood the hospital.