Medical Technology

From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide.

In this book, Prusiner tells the remarkable story of his discovery of prions - infectious proteins that replicate and cause disease but surprisingly contain no genetic material - and reveals how superb and meticulous science is actually practiced with talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases.

In this transporting book, David Oliver Relin shines a light on the work of Geoffrey Tabin and Sanduk Ruit, gifted ophthalmologists who have dedicated their lives to restoring sight to some of the world’s most isolated, impoverished people through the Himalayan Cataract Project, an organization they founded in 1995. Tabin was the high-achieving bad boy of Harvard Medical School, an accomplished mountain climber and adrenaline junkie as brilliant as he was unconventional.

Dr. Joel Salinas is a Harvard-trained researcher and neurologist with extraordinary gifts that provide him unique access to his patients and enable him to experience life in an extraordinary way. He has mirror-touch synesthesia, a neurological trait that allows him to feel others' emotions and physical sensations. Susceptible to the pain and discomfort of his patients, Salinas uses his heightened empathic ability - what he calls "compulsory mindfulness" - to help understand and better treat their conditions.

The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the 20th century. Into this crisis stepped Walter Freeman, MD, who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman's documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.

In gripping prose, one of the world's leading cardiac surgeons lays bare both the wonder and the horror of a life spent a heartbeat away from death. When Stephen Westaby witnessed a patient die on the table during open-heart surgery for the first time, he was struck by the quiet, determined way the surgeons walked away. As he soon understood, this detachment is a crucial survival strategy in a profession where death is only a heartbeat away. In Open Heart, Westaby reflects on over 11,000 surgeries, showing us why the procedures have never become routine and will never be.

The Headache Godfather traces the life of Seymour Diamond, MD, who was born in 1925, the son of Jewish immigrants from Ukraine and Slovakia, in Chicago, Illinois. Dr. Diamond revolutionized the practice of headache as a medical specialty when he opened the United States' first private headache practice, the Diamond Headache Clinic, in 1974. It quickly became a headache haven for sufferers from around the world.

The United States is embarking on a medical revolution. Supporters of personalized, or precision, medicine—the tailoring of health care to our genomes—have promised to usher in a new era of miracle cures. Advocates of this gene-guided health-care practice foresee a future where skyrocketing costs can be curbed by customization and unjust disparities are vanquished by biomedical breakthroughs. Progress, however, has come slowly, and with a price too high for the average citizen.

In this compelling memoir, Jane Hawking relates the inside story of her extraordinary marriage. As Stephen's academic renown soared, his body was collapsing under the assaults of motor neurone disease, and Jane's candid account of trying to balance his 24-hour care with the needs of their growing family is inspirational. This is a book about optimism, love and change that will resonate with listeners everywhere.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Nine million Americans are touched by aneurysms during their lifetimes. This is one story of love. Brainstorm is the candid and powerful memoir of the author's harrowing experience of an aneurysm and his road to recovery. It is a journey of love and devotion and a clash of medical beliefs and countercultures.

Imagine undergoing an operation without anesthesia performed by a surgeon who refuses to sterilize his tools - or even wash his hands. This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the 19th century. Although he died at just 48, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.

James Barry was one of the most outstanding doctors of the 19th century – a brilliant surgeon, a tireless campaigner for medical reform, and a compassionate Inspector-General of the Army. But throughout a long and distinguished career an air of secrecy, even of scandal, always clung to Barry. The shrill voice, the diminutive build, the almost ostentatious humanity – all struck a discordant note in the stiff, conventional world of the officers’ mess. Only after the doctor’s death in 1865 did the incredible truth come to light: Dr. James Barry was a woman.

What if every business owner or manager could combine cutting-edge technology with the warmth of personal connection to keep customers coming back for more and sending their friends and family? Drawing lessons from the industry-leading business practices at One Medical, a brand transforming the customer experience in healthcare, All Business Is Personal gives readers tools to blend the powerful benefits of today’s rapidly improving technology with individuals’ unique talents, all in the name of providing only the best for their customers.

The "absorbing and powerful" (Wall Street Journal) story of two pioneering suffragette doctors who shattered social expectations and transformed modern medicine during World War I. In No Man's Land, Wendy Moore illuminates this turbulent moment of global war and pandemic when women were, for the first time, allowed to operate on men. Their fortitude and brilliance serve as powerful reminders of what women can achieve against all odds.

Anyone who has seen a child recover from a wound or a broken bone knows that kids are made to heal. Their bodies are more resilient, more adaptive, and far more able to withstand acute stress than adults'. In this inspiring memoir, Dr. Kurt Newman draws from his long experience as a pediatric surgeon working at one of our nation's top children's hospitals to make the case that children are more than miniature adults.

It wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting 50 years of false starts, abysmal failures, and miraculous triumphs.

An inside account of the fight to contain the world's deadliest diseases - and the panic and corruption that make them worse. The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others - and how we could do more to prevent their return. It is both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

Hear about some of the world's most messed-up medical mishaps. Find out how each procedure, tool, or surgery failed, the basic science that was missed, and what doctors learned from their mistakes.

In the early days of the Cold War, a spirit of desperate scientific rivalry birthed a different kind of space race: not the race to outer space that we all know, but a race to master the inner space of the human body. While surgeons on either side of the Iron Curtain competed to become the first to transplant organs like the kidney and heart, a young American neurosurgeon had an even more ambitious thought: Why not transplant the brain?