Modern Genetics

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the 20-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics.

We are living through the most prosperous age in all of human history, yet we are listless, divided, and miserable. Wealth and comfort are unparalleled, but our political landscape is unmoored, and rates of suicide, lone­liness, and chronic illness continue to skyrocket. How do we explain the gap between these truths? And how should we respond? For evolutionary biologists Heather Heying and Bret Weinstein, the cause of our troubles is clear: The accelerat­ing rate of change in the modern world has outstripped the capacity of our brains and bodies to adapt.

Thanks to the popularity of personal genetic testing services, it's now easier than ever to get information about our own unique DNA - but who does this information really benefit? And, as genome editing and gene therapy transform the healthcare landscape, what do we gain - and what might we give up in return?

You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.

A significant number of Americans, especially evangelical Christians, believe Earth and humankind were created in their present form sometime in the last 10,000 years or so - the rationale being that this is (presumably) the story told in the book of Genesis. Within that group, any threatening scientific evidence that suggests otherwise is rejected or, when possible, retrofitted into a creationist worldview.

We are all familiar with the "march of progress," the representation of evolution that depicts a series of apelike creatures becoming progressively taller and more erect before finally reaching the upright human form. Its emphasis on linear progress has had a decisive impact on public understanding of evolution, yet the image contradicts modern scientific conceptions of evolution as complex and branching.

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

Evolutions brings to life the latest scientific thinking on the birth of the universe and the solar system, the journey from a single cell all the way to our human minds. Reawakening our sense of wonder and terror at the world around us and within us, Oren Harman uses modern science to create new and original mythologies.

A professor, biologist, and physiologist argues that modern Darwinism's materialist and mechanistic biases have led to a scientific dead end, unable to define what life is - and only an openness to the qualities of "purpose and desire" will move the field forward. J. Scott Turner contends, "To be scientists, we force ourselves into a Hobson's choice on the matter: accept intentionality and purposefulness as real attributes of life, which disqualifies you as a scientist; or become a scientist and dismiss life's distinctive quality from your thinking."

It is difficult to conceive of the vast scale of the history of life on Earth, from the very first living organisms sparking into life in hydrothermal deep-sea vents to the dizzying diversity of life today. The evolution of life is a sweeping epic of a tale, with twists and turns, surprising heroes and unlikely survivors. The Earth beautifully distils this complex story into a meaningful scale. In taking a closer look at 47 carefully selected organisms over 15 periods in our planetary history, this audiobook tells the whole story of life on Earth.

This a judicious excerpt from the writings of the famous evolutionist Ernst Haeckel, a famous Darwin-influenced evolutionist of the late 19th and early 20th century. Focuses on natural selection and the development of human evolution.

For an era in which Darwin is more talked about than read, Daniel Duzdevich offers a clear, modern English rendering of Darwin's first edition. Neither an abridgement nor a summary, this version might best be described as a "translation" for contemporary English listeners. A monument to reasoned insight, the Origin illustrates the value of extensive reflection, carefully gathered evidence, and sound scientific reasoning.

Lucy Morrigan, a young genetic researcher, decides to clone her grandmother in this modern, heartwarming twist on Mary Shelley's classic. Lucy lives with her boyfriend, Gray, in her crumbling family mansion and works in the high-tech basement lab she inherited from her father. Frustrated by her unsuccessful attempts to win tenure and bear a child, she takes drastic measures to achieve both. Hoping for a baby, she instead brings to life 22-year-old Mary.

Es ist eine Frage, die sich Menschen seit Tausenden von Jahren stellen: Woher kommen wir? Nach Antworten suchen Fachleute auch in unserer DNA – und hier decken sie einige Sensationen auf. Im Erbgut von Homo sapiens befinden sich nämlich Abschnitte, die gar nicht von den Ahnen unserer Spezies stammen. Neandertaler, Denisovianer und weitere, noch unbekannte Vettern der Gattung Homo haben sich offenbar mit unseren Vorfahren gepaart und so zu unserem Genom beigetragen. Und auch unsere jüngere evolutionäre Vergangenheit hat markante Spuren in unseren Genen hinterlassen.

In Unfit for Purpose, biologist and broadcaster Adam Hart explores the mismatch between our fundamental biology and the modern world we have created. In each chapter Adam reveals the many ways in which biological adaptations that evolved to help us survive and thrive now work against us. For example, in the modern world stress is a killer, but how did 'fight or flight' instincts turn from life-savers to life-takers? Obesity might be a disease now, but is it really just a troublesome side-effect of our complex evolutionary past?

Sandy thinks there's something wrong with her resident's new hearing aid. It's picking up numbers that only he can detect. Evil carer Lisa thinks he's just an attention seeking senile old imbecile. They're counting down, but to what?

Human beings have astonishing genetic vulnerabilities. More than half of us will die from complex diseases that trace directly to those vulnerabilities, and the modern world we've created places us at unprecedented risk from them. In It Takes a Genome, Greg Gibson posits a revolutionary new hypothesis: Our genome is out of equilibrium, both with itself and its environment. Simply put, our genes aren't coping well with modern culture.