Professional Science

From insulin comas and lobotomy to incarceration and exile, Walter Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade's "Lithium Salts in the Treatment of Psychotic Excitement" described, for the first time, lithium's astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide.

How I Became a Human Being is Mark O'Brien’s account of his struggles to lead an independent life despite a lifelong disability. In 1955 he contracted polio and became permanently paralyzed from the neck down. O'Brien describes growing up without the use of his limbs, his adolescence struggling with physical rehabilitation and suffering the bureaucracy of hospitals and institutions, and his adult life as an independent student and writer. Despite his physical limitations, O'Brien crafts a narrative that is as rich and vivid as the life he led.

In 1942, a team at the University of Chicago achieved what no one had before: a nuclear chain reaction. At the forefront of this breakthrough stood Enrico Fermi. Straddling the ages of classical physics and quantum mechanics, equally at ease with theory and experiment, Fermi truly was the last man who knew everything - at least about physics. But he was also a complex figure who was a part of both the Italian Fascist Party and the Manhattan Project, and a less-than-ideal father and husband who nevertheless remained one of history's greatest mentors.

Few recognize how the Great War, the industrialized slaughter that bled Europe from 1914 to 1918, shaped Einstein’s life and work. While Einstein never held a rifle, he formulated general relativity blockaded in Berlin, literally starving. He lost 50 pounds in three months, unable to communicate with his most important colleagues. Some of those colleagues fought against rabid nationalism; others were busy inventing chemical warfare - scientists trapped in the power plays of empire. Meanwhile, Einstein struggled to craft relativity and persuade the world that it was correct.

When Isaac Newton died in 1727 without a will, he left behind a wealth of papers that, when examined, gave his followers and his family a deep sense of unease. Some of what they contained was wildly heretical and alchemically obsessed, hinting at a Newton altogether stranger and less palatable than the one enshrined in Westminster Abbey as the paragon of English rationality. These manuscripts had the potential to undermine not merely Newton's reputation, but that of the scientific method he embodied.

Few scientists have enthralled more people than Richard P. Feynman, the Nobel Prize winner and best-selling author of Six Easy Pieces and Surely You're Joking, Mr. Feynman! Beloved for his engaging character and zest for life, he is an American icon. In this selection of letters, Feynman's towering genius and singular personality shine like dazzling stars.

In the tradition of #Girlboss and Mindy Kaling's Is Everyone Hanging Out Without Me?, a funny, quirky, and inspiring memoir from online entertainment mogul, actress, and "queen of the geeks" Felicia Day about her unusual upbringing, her rise to Internet stardom, and embracing her individuality to find success in Hollywood.

Unravel the enigmatic depths of Albert Einstein's mind in "Ideas and Opinions." This captivating collection, compiled by the master himself, unveils his diverse perspectives on science, philosophy, social issues, and even religion. Delve into the workings of relativity, ponder his nuanced views on faith, and journey with him as he advocates for peace, justice, and societal transformation.

Death was conspicuously absent during Rachel's medical training. Instead, her education focused entirely on learning to save lives, and was left wanting when it came to helping patients and their families face death. She came to specialize in palliative medicine because it is the one specialty in which the quality, not quantity of life truly matters. In the same year she started to work in a hospice, Rachel was forced to face tragedy in her own life when her father was diagnosed with terminal cancer.

We have lost the war on cancer. We spend $150 billion each year treating it, yet - a few innovations notwithstanding - a patient with cancer is as likely to die of it as one was 50 years ago. Most new drugs add mere months to one's life at agonizing physical and financial cost. In The First Cell, Azra Raza offers a searing account of how both medicine and our society (mis)treats cancer, how we can do better, and why we must.

As a child, Jory Fleming was wracked by uncontrollable tantrums, had no tolerance for people, and couldn’t manage the outside world. Slightly more than a decade later, he was bound for England, selected to attend one of the world’s premier universities. How to Be Human explores life amid a world constructed for neurotypical brains when yours is not. But the miracle of this book is that instead of dwelling on Jory’s limitations, those who inhabit the neurotypical world will begin to better understand their own.

Aristotle said that philosophy begins with wonder, and the first Western philosophers developed theories of the world which express simultaneously their sense of wonder and their intuition that the world should be comprehensible. But their enterprise was by no means limited to this proto-scientific task. Through, for instance, Heraclitus's enigmatic sayings, the poetry of Parmenides and Empedocles, and Zeno's paradoxes, the Western world was introduced to metaphysics, rationalist theology, ethics, and logic.

Much has been written about Neil Armstrong, America's modern hero and history's most famous space traveler. Yet, shy of fame and never one to steal the spotlight, Armstrong was always reluctant to discuss his personal side of events. Here for the first time is the definitive story of Neil's life of flight he shared for five decades with a trusted friend - Jay Barbree.

There is growing evidence that Trump has spent decades cultivating ties to corrupt Russians and the post-Soviet state. In Trump/Russia: A Definitive History, Seth Hettena chronicles the many years Trump has spent wooing Russian money and power. From the collapse of his casino empire - which left Trump desperate for cash - and his first contacts with Russian deal makers and financiers, on up to the White House, Hettena reveals the myriad of shady people, convoluted dealings, and strange events that suggest how indebted to Russia our 45th president might be.

Jadie never spoke. She never laughed, or cried, or uttered any sound. Despite efforts to reach her, Jadie remained locked in her own troubled world - until one remarkable teacher persuaded her to break her self-imposed silence. Nothing in all of Torey Hayden's experience could have prepared her for the shock of what Jadie told her - a story too horrendous for Torey's professional colleagues to acknowledge.

In Archaeology from Space, Sarah Parcak shows the evolution, major discoveries, and future potential of the young field of satellite archaeology. From surprise advancements after the declassification of spy photography, to a new map of the mythical Egyptian city of Tanis, she shares her field's biggest discoveries, revealing why space archaeology is not only exciting, but urgently essential to the preservation of the world's ancient treasures.

In The Millionaire Next Door, best selling author Thomas Stanley identified the millionaires around you. In The Millionaire Mind, he told you how they think. Now, he tells you how to get their business.

A pioneering neuroscientist shares his story of growing up in one of Miami's toughest neighborhoods and how it led him to his groundbreaking work in drug addiction. As a youth, Carl Hart didn't realize the value of school; he studied just enough to stay on the basketball team. At the same time, he was immersed in street life. Today he is a cutting-edge neuroscientist - Columbia University's first tenured African American professor in the sciences.

In a field of PhDs, Tim Samaras didn’t attend a day of college in his life. He chased storms with brilliant tools of his own invention and pushed closer to the tornado than anyone else ever dared. When he achieved what meteorologists had deemed impossible, it was as if he had snatched the fire of the gods. Yet even as he transformed the field, Samaras kept on pushing.

Steven Donziger, a self-styled social activist and Harvard educated lawyer, signed on to a budding class action lawsuit against multinational Texaco. The suit sought reparations for the Ecuadorian peasants and tribes people whose lives were affected by decades of oil production near their villages and fields. During twenty years of legal hostilities in federal courts in Manhattan and remote provincial tribunals in the Ecuadorian jungle, Donziger and Chevron's lawyers followed fierce no-holds-barred rules.