After years away, Astrid Nilsson has returned home to Colorado, hoping to become Fairplay’s second doctor...and to find healing for her reoccurring consumption. Spirited and independent, Astrid doesn’t want her illness to be a burden to those she loves, so she has resisted getting serious about any man.

Greta Nilsson's trip west to save her ailing little sister, Astrid, could not have gone more wrong. First, bandits hold up her stagecoach, stealing all her money. Then, upon arriving in Fairplay, Colorado, she learns the man she was betrothed to as a mail-order bride has died. Homeless, penniless, and jobless, Greta and her sister are worse off than when they started.

Lord Elliott Mayfield sees the new generation of his family moving in the same direction of bad matches and scandalous relationships as the last. In hopes to change their course, he establishes a "marriage campaign" to motivate them to improve themselves through making respectable matches. Peter, Elliott's eldest nephew, thinks the entire idea is ridiculous. A widower with two young daughters, he simply needs a governess, not a wife. Julia Hollingsworth has the credentials and the experience, but is too young and pretty for such a job. So why can't he stop thinking about her?

Josephine Nordegren is one of three sisters who grew up nearly wild in southwestern Colorado. She has the archery skills of Robin Hood and the curiosity of the Little Mermaid, fascinated by but locked away from the forbidden outside world - a world she's been raised to believe killed her parents. When David Warden, a rancher, brings in a herd much too close to the girls' secret home, her older sister especially is frightened, but Jo is too interested to stay away.

Living in London's poorest slum, Mercy Wilkins has little hope of a better life. When she's offered an opportunity to join a bride ship sailing to British Columbia, she agrees. After witnessing so much painful heartache and loss in the slums, the bride ship is her only prospect to escape a bleak future, not only for herself but, she hopes, someday for her sister. Wealthy and titled Joseph Colville leaves home and takes to the sea - as ship's surgeon - in order to escape the pain of losing his family. When Mercy becomes his assistant, the two must fight against a forbidden love.