Little Marek, the abused and delusional son of the village shepherd, believes his mother died giving birth to him. One of Marek’s few consola­tions is his enduring bond with the blind village midwife, Ina, who suckled him when he was a baby. For some people, Ina’s ability to receive trans­missions of sacred knowledge from the natural world is a godsend. For others, Ina’s home in the woods is a godless place.

Salem, Massachusetts, 1851: McGlue is in the hold, still too drunk to be sure of name or situation or orientation - he may have killed a man. That man may have been his best friend. Intolerable memory accompanies sobriety.

Our narrator should be happy, shouldn't she? She's young, thin, pretty, a recent Columbia graduate; she works an easy job at a hip art gallery and lives in an apartment on the Upper East Side of Manhattan paid for, like the rest of her needs, by her inheritance. But there is a dark and vacuous hole in her heart, and it isn't just the loss of her parents, or the way her Wall Street boyfriend treats her, or her sadomasochistic relationship with her best friend, Reva. It's the year 2000 in a city aglitter with wealth and possibility; what could be so terribly wrong?

Deep underground, 39 women live imprisoned in a cage. Watched over by guards, the women have no memory of how they got there, no notion of time, and only a vague recollection of their lives before. As the burn of electric light merges day into night and numberless years pass, a young girl—the 40th prisoner—sits alone and outcast in the corner. Soon she will show herself to be the key to the others’ escape and survival in the strange world that awaits them above ground.

Toru, a serious young college student in Tokyo, is devoted to Naoko, a beautiful and introspective young woman, but their mutual passion is marked by the tragic death of their best friend years before. As Naoko retreats further into her own world, Toru finds himself drawn to a fiercely independent and sexually liberated young woman.