Lucas Vega is obsessed with the death of Candace Swain, who left a sorority party one night and never came back. Her body was found after two weeks, but the case has grown cold. Three years later while interning at the medical examiner's, Lucas discovers new information, but the police are not interested.

Detective Kara Quinn, on leave from the LAPD, is on an early morning jog in her hometown of Liberty Lake when she comes upon the body of a young nurse. The manner of death shows a pattern of highly controlled rage. Meanwhile in DC, FBI Special Agent Mathias Costa is staffing his newly minted Mobile Response Team. Word reaches Matt that the Liberty Lake murder fits the profile of the compulsive Triple Killer. It will be the first case for the MRT. This time, they have a chance to stop this zealous, if elusive, killer before he strikes again.

After five years in hiding from their murderous father, the day Kristen and Ryan McIntyre have been dreading has arrived: Boyd McIntyre, head of a Los Angeles crime family, has at last tracked his kids to a small Montana town and is minutes away from kidnapping them. They barely escape in a small plane, but gunfire hits the fuel line. The pilot, a man who has been raising them as his own, manages to crash land in the middle of the Montana wilderness. The siblings hike deep into the woods, searching desperately for safety—unaware of the severity of the approaching storm.

Alex Cross is a homicide detective with a Ph.D. in psychology. He works and lives in Southeast D.C. and looks like Muhammad Ali in his prime. He's a tough guy from a tough part of town who wears Harris Tweed jackets and likes to relax by banging out Gershwin tunes on his baby grand piano. But he also has two adorable kids of his own, and they are his own special vulnerabilities.

Forensic genealogist Rowan Healy has made a name for herself by helping investigators trace the family trees of violent criminals who have eluded justice for years. But the pressure of police cases left her burned out, and she’s shifted her focus to helping adoptees find their biological parents.