Mina is trying to focus on her job as a flight attendant, not the problems of her five-year-old daughter back home or the fissures in her marriage. But the plane has barely taken off when Mina receives a chilling note from an anonymous passenger, someone intent on ensuring the plane never reaches its destination. Someone who needs Mina's assistance and who knows exactly how to make her comply. It's 20 hours to landing. A lot can happen in 20 hours....

Eva Hansen wakes in the hospital after being struck by lightning and discovers her mother, Kat, has been murdered. Eva was found unconscious down the street. She can’t remember what happened, but the police are highly suspicious of her. Determined to clear her name, Eva heads from Seattle to London - Kat’s former home - for answers. But as she unravels her mother’s carefully held secrets, Eva soon realizes that someone doesn’t want her to know the truth. And with violent memories beginning to emerge, Eva doesn’t know who to trust. Least of all herself.

When Fiona Lawson comes home to find strangers moving into her house, she's sure there's been a mistake. She and her estranged husband, Bram, have a modern coparenting arrangement: bird's nest custody, where each parent spends a few nights a week with their two sons at the prized family home to maintain stability for their children. But the system built to protect their family ends up putting them in terrible jeopardy. In a domino effect of crimes and misdemeanors, the nest comes tumbling down.

Nina Landry awakens on her 40th birthday, anticipating a day filled with excitement. She, her new boyfriend, and her two children are taking a trip - leaving their home on Sandling Island, off the coast of England, for a dream vacation. As soon as her 15-year-old daughter, Charlie, returns from a sleepover, they can get ready to leave. But Charlie doesn’t come home at the expected time. As minutes and then hours tick by, Nina’s annoyance soon changes to concern, and then to a chilling certainty that something terrible has happened.

Anna Hart is a seasoned missing persons detective in San Francisco with far too much knowledge of the darkest side of human nature. When tragedy strikes her personal life, Anna, desperate and numb, flees to the Northern California village of Mendocino to grieve. She lived there as a child with her beloved foster parents, and now she believes it might be the only place left for her. Yet the day she arrives, she learns that a local teenage girl has gone missing.

London cycle courier Astrid Bell has known most of her housemates for years, but while they have a tangled history together - romantic pairings, one-night stands, friendships - they each have secrets. Astrid is on her way home one day when her neighbor accidentally knocks her off her bike. Suffering a few bruises, her roommates help her home. The next day, they learn that same neighbor was bludgeoned to death only hours after the accident.

Though she may be a murderer, Ruby is not a sociopath. She is an animal-loving therapist with a thriving practice. She’s felt empathy and sympathy. She’s had long-lasting friendships and relationships, and has a husband, Jason, whom she adores. But the homicide detectives at Miami Beach PD are not convinced of her happy marriage. When we meet Ruby, she is in a police interrogation room, being accused of Jason’s murder.

New friends Sam, Margaret and Diana are thrilled to be getting out of the city for a girls’ weekend - they’ve bonded over their messy divorces, and every mile on the odometer feels like another step towards putting their exes in the past. But when car trouble halfway into their trip strands them in the most unlikely of mountain towns, they come face-to-face with the hurts and betrayals they were so desperate to leave behind. When Diana doesn't return home after a night out, Sam and Margaret's search for her reveals just how little they know about their friend.

Abbie awakens in a daze with no memory of who she is or how she landed in this unsettling condition. The man by her side claims to be her husband. He’s a titan of the tech world, the founder of one of Silicon Valley’s most innovative start-ups. He tells Abbie that she is the perfect wife. He says she had a terrible accident five years ago and that, through a huge technological breakthrough, she has been brought back from the abyss. But as Abbie pieces together memories of her marriage, she begins to question her husband’s motives - and his version of events.

Perched atop a hill in the tiny town of Marchburg, Virginia, The Goode School is a prestigious prep school known as a Silent Ivy. The boarding school of choice for daughters of the rich and influential, it accepts only the best and the brightest. Its elite status, long-held traditions and honor code are ideal for preparing exceptional young women for brilliant futures at Ivy League universities and beyond. But a stranger has come to Goode, and this ivy has turned poisonous.

Lex Gracie doesn't want to think about her family. She doesn't want to think about growing up in her parents' House of Horrors. And she doesn't want to think about her identity as Girl A: the girl who escaped, the eldest sister who freed her older brother and four younger siblings. It's been easy enough to avoid her parents - her father never made it out of the House of Horrors he created, and her mother spent the rest of her life behind bars. But when her mother dies in prison and leaves Lex and her siblings the family home, she can't run from her past any longer.

Pete Riley answers the door one morning and lets in a parent's worst nightmare. On his doorstep is Miles Lambert, a stranger who breaks the devastating news that Pete's son, Theo, isn't actually his son - he is the Lamberts', switched at birth by an understaffed hospital while their real son was sent home with Miles and his wife, Lucy. For Pete, his partner Maddie, and the little boy they've been raising for the past two years, life will never be the same again.

There is a serial killer on the loose preying on vulnerable women. The only identifiable mark the killer leaves are letters - sometimes one, sometimes two - all carved into the torsos of his victims. Together, they spell “Sydney”. When he grabs Daisy Dawson, he believes he has found his next victim. But despite her small stature, she fights back with an expertise that quickly frees her. Before fleeing the scene, Daisy also manages to grab what proves to be crucial evidence: a necklace from around the killer’s neck.

For the lucky among us, life is what you make of it, but for Dixie Wheeler, the theme music for her story was chosen by another long ago, on the day her father butchered her mother and brothers and then slashed a knife across his own throat. Only one-year-old Dixie was left alive, infamously known as Baby Blue for the song left playing in the aftermath of the slaughter. Twenty-five years later, Dixie is still desperate for a connection to the family she can’t remember, so when her childhood home goes up for sale, Dixie sets aside all reason and moves in.

Newlyweds Sam Statler and Annie Potter are head over heels, and excited to say good-bye to New York city and start a life together in Sam's sleepy hometown upstate. Or, it turns out, a life where Annie spends most of her time alone while Sam, her therapist husband, works long hours in his downstairs office, tending to the egos of his (mostly female) clientele. Little does Sam know that through a vent in his ceiling, every word of his sessions can be heard from the room upstairs.